Zobrazeno 1 - 10
of 92
pro vyhledávání: '"Sergio Dall'angelo"'
Autor:
Karen J. Thompson, Sonia Watson, Chiara Zanato, Sergio Dall'Angelo, Joriene C. De Nooij, Bethany Pace‐Bonello, Fiona C. Shenton, Helen E. Sanger, Beverly A. Heinz, Lisa M. Broad, Noelle Grosjean, Jessica R. McQuillian, Marina Dubini, Susan Pyner, Iain Greig, Matteo Zanda, David Bleakman, Robert W. Banks, Guy S. Bewick
Publikováno v:
Experimental Physiology, Vol 109, Iss 1, Pp 81-99 (2024)
Abstract A metabotropic glutamate receptor coupled to phospholipase D (PLD‐mGluR) was discovered in the hippocampus over three decades ago. Its pharmacology and direct linkage to PLD activation are well established and indicate it is a highly atypi
Externí odkaz:
https://doaj.org/article/81a681306fa94df7a114941db1591a5b
Publikováno v:
Insights into Imaging, Vol 12, Iss 1, Pp 1-21 (2021)
Abstract Lung cancer has the highest mortality rate of any tumour type. The main driver of lung tumour growth and development is uncontrolled cellular proliferation. Poor patient outcomes are partly the result of the limited range of effective anti-c
Externí odkaz:
https://doaj.org/article/42c0308816694d15955711079da855c4
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 7, Iss 9, Pp 1580-1593 (2020)
Abstract Objective The purpose of the study was to determine the extent and role of systemic hypoxia in the pathogenesis of spinal muscular atrophy (SMA). Methods Hypoxia was assayed in vivo in early‐symptomatic (postnatal day 5) SMA‐model mice b
Externí odkaz:
https://doaj.org/article/cd313f6cbcdb4f948533e890513364d8
Autor:
Alessandro Colombano, Luca Dalponte, Sergio Dall'Angelo, Claudia Clemente, Mohannad Idress, Ahmad Ghazal, Wael E. Houssen
Publikováno v:
Angewandte Chemie. 135
Autor:
Claudia Clemente, Nicholas Johnson, Xiaodan Ouyang, Rafael V. Popin, Sergio Dall'Angelo, Matti Wahlsten, Jouni Jokela, Alessandro Colombano, Brunello Nardone, David P. Fewer, Wael E. Houssen
Publikováno v:
Chemical Communications. 58:12054-12057
Cyanobactins are linear and cyclic post-translationally modified peptides. Here we show that the prenyl-D-Arg-containing autum-nalamide A is a member of the cyanobactin family. Biochemical assays demonstrate that the AutF prenyltransferase targets th
Autor:
Katja Schaefer, Ivy M. Dambuza, Sergio Dall’Angelo, Raif Yuecel, Marcel Jaspars, Laurent Trembleau, Matteo Zanda, Gordon D. Brown, Mihai G. Netea, Neil A. R. Gow
Publikováno v:
Microorganisms, Vol 8, Iss 7, p 1066 (2020)
The discovery of liquid water at several locations in the solar system raises the possibility that microbial life may have evolved outside Earth and as such could be accidently introduced into the Earth’s ecosystem. Unusual sugars or amino acids, l
Externí odkaz:
https://doaj.org/article/178054797e034344bd23104665d8fa7a
Autor:
Sergio Dall'Angelo, Maria Cristina Bellucci, Alessandro Volonterio, Alasdair Leeson-Payne, Justin J. Rochford, Yitzhak Tor, Jeffery D Esko, Kaivin Hadidi
Publikováno v:
Organic & Biomolecular Chemistry. 19:6513-6520
Guanidinoglycosides are a class of non-cytotoxic molecular transporters capable of delivering high molecular weight bioactive cargos into cells at low nanomolar concentrations. Efficient bioconjugation with guanidinoglycosides has been previously dem
Autor:
Mirko Magni, Sergio Dall'Angelo, Clara Baldoli, Emanuela Licandro, Luigi Falciola, Patrizia R. Mussini
Publikováno v:
Electrochemical Science Advances. 2
Autor:
Kirsten Laws, Graeme I Murray, Keith Kerr, Fergus McKiddie, Sergio Dall’Angelo, Matteo Zanda, Ian Fleming, Leslie Samuel
Publikováno v:
Case Reports and Images In Oncology. :1-5
Introduction: Colorectal cancer risk stratification traditionally focuses on tumor node metastasis staging. Seemingly equivalent tumors can differ unpredictably in prognosis; more sophisticated quantification and stratification methods are required t
Autor:
Andrea Testa (1), Sergio Dall'Angelo (1), Marco Mingarelli (1), Andrea Augello (1), Lutz Schweiger (1), Andrew Welch (1), Charles S. Elmore (2), Dana Dawson (1), Pradeep Sharma (3), Matteo Zanda (1
Publikováno v:
Contrast Media & Molecular Imaging, Vol 2018 (2018)
Contrast media and molecular imaging (Online) 2018 (2018): 1–10. doi:10.1155/2018/3064751
info:cnr-pdr/source/autori:Andrea Testa (1), Sergio Dall'Angelo (1), Marco Mingarelli (1), Andrea Augello (1), Lutz Schweiger (1), Andrew Welch (1), Charles S. Elmore (2), Dana Dawson (1), Pradeep Sharma (3) and Matteo Zanda (1,4)/titolo:Preclinical Evaluation of [18F]LCATD as a PET Tracer to Study Drug-Drug Interactions Caused by Inhibition of Hepatic Transporters/doi:10.1155%2F2018%2F3064751/rivista:Contrast media and molecular imaging (Online)/anno:2018/pagina_da:1/pagina_a:10/intervallo_pagine:1–10/volume:2018
Contrast media and molecular imaging (Online) 2018 (2018): 1–10. doi:10.1155/2018/3064751
info:cnr-pdr/source/autori:Andrea Testa (1), Sergio Dall'Angelo (1), Marco Mingarelli (1), Andrea Augello (1), Lutz Schweiger (1), Andrew Welch (1), Charles S. Elmore (2), Dana Dawson (1), Pradeep Sharma (3) and Matteo Zanda (1,4)/titolo:Preclinical Evaluation of [18F]LCATD as a PET Tracer to Study Drug-Drug Interactions Caused by Inhibition of Hepatic Transporters/doi:10.1155%2F2018%2F3064751/rivista:Contrast media and molecular imaging (Online)/anno:2018/pagina_da:1/pagina_a:10/intervallo_pagine:1–10/volume:2018
The bile acid analogue [18F]LCATD (LithoCholic Acid Triazole Derivative) is transported in vitro by hepatic uptake transporters such as OATP1B1 and NTCP and efflux transporter BSEP. In this in vivo “proof of principle” study, we tested if [18F]LC