Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Sergio Crespo‐Garcia"'
Autor:
Christophe Roubeix, Caroline Nous, Sébastien Augustin, Kaitryn E. Ronning, Thibaud Mathis, Frédéric Blond, Pauline Lagouge-Roussey, Sergio Crespo-Garcia, Patrick M. Sullivan, Emmanuel L. Gautier, Nadine Reichhart, José-Alain Sahel, Marie E. Burns, Michel Paques, Torben Lykke Sørensen, Olaf Strauss, Xavier Guillonneau, Cécile Delarasse, Florian Sennlaub
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-17 (2024)
Abstract Age-related macular degeneration (AMD) is invariably associated with the chronic accumulation of activated mononuclear phagocytes in the subretinal space. The mononuclear phagocytes are composed of microglial cells but also of monocyte-deriv
Externí odkaz:
https://doaj.org/article/15a2fe8398d24307833b4ae362a8cd9b
Autor:
Gaëlle Mawambo, Malika Oubaha, Yusuke Ichiyama, Guillaume Blot, Sergio Crespo-Garcia, Agnieszka Dejda, François Binet, Roberto Diaz-Marin, Christina Sawchyn, Mikhail Sergeev, Rachel Juneau, Randal J. Kaufman, El Bachir Affar, Frédérick A. Mallette, Ariel M. Wilson, Przemyslaw Sapieha
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-14 (2023)
Abstract Cellular adaptation to low oxygen tension triggers primitive pathways that ensure proper cell function. Conditions of hypoxia and low glucose are characteristic of injured tissues and hence successive waves of inflammatory cells must be suit
Externí odkaz:
https://doaj.org/article/43e12a5532544c0686ece219c67a0571
Autor:
Masayuki Hata, Maki Hata, Elisabeth M.M.A. Andriessen, Rachel Juneau, Frédérique Pilon, Sergio Crespo-Garcia, Roberto Diaz-Marin, Vera Guber, Francois Binet, Frédérik Fournier, Manuel Buscarlet, Caroline Grou, Virginie Calderon, Emilie Heckel, Heather J. Melichar, Jean-Sebastien Joyal, Ariel M. Wilson, Przemyslaw Sapieha
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 4 (2023)
Pathological neovascularization in age-related macular degeneration (nvAMD) drives the principal cause of blindness in the elderly. While there is a robust genetic association between genes of innate immunity and AMD, genome-to-phenome relationships
Externí odkaz:
https://doaj.org/article/9f2a87e18ff945d5802827bcdccf47e0
Autor:
Roberto Diaz-Marin, Sergio Crespo-Garcia, Ariel M. Wilson, Manuel Buscarlet, Agnieszka Dejda, Frédérik Fournier, Rachel Juneau, Thierry Alquier, Przemyslaw Sapieha
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract The beneficial effects of brown adipose tissue (BAT) on obesity and associated metabolic diseases are mediated through its capacity to dissipate energy as heat. While immune cells, such as tissue-resident macrophages, are known to influence
Externí odkaz:
https://doaj.org/article/038531e383294c999354f1395541bdba
Autor:
Elisabeth M M A Andriessen, François Binet, Frédérik Fournier, Masayuki Hata, Agnieszka Dejda, Gaëlle Mawambo, Sergio Crespo‐Garcia, Frédérique Pilon, Manuel Buscarlet, Karine Beauchemin, Véronique Bougie, Garth Cumberlidge, Ariel M Wilson, Steve Bourgault, Flavio A Rezende, Normand Beaulieu, Jean‐Sébastien Delisle, Przemyslaw Sapieha
Publikováno v:
EMBO Molecular Medicine, Vol 13, Iss 5, Pp 1-14 (2021)
Abstract Age‐related macular degeneration (AMD) in its various forms is a leading cause of blindness in industrialized countries. Here, we provide evidence that ligands for neuropilin‐1 (NRP1), such as Semaphorin 3A and VEGF‐A, are elevated in
Externí odkaz:
https://doaj.org/article/4736161cc8494b3eae5cc70e5a854d66
Autor:
Christina Nürnberg, Norbert Kociok, Claudia Brockmann, Timo Lischke, Sergio Crespo-Garcia, Nadine Reichhart, Susanne Wolf, Ria Baumgrass, Sabine A. Eming, Sandra Beer-Hammer, Antonia M. Joussen
Publikováno v:
Data in Brief, Vol 16, Iss , Pp 489-500 (2018)
The dataset presented in this article complements the article entitled “Myeloid cells contribute indirectly to VEGF expression upon hypoxia via activation of Müller cells” (C. Nürnberg, N. Kociok, C. Brockmann, T. Lischke, S. Crespo-Garcia, N.
Externí odkaz:
https://doaj.org/article/a59d4a362e024bc08339f3c25c04f717
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 9, p 4481 (2021)
Diabetic retinopathy is characterized by dysfunction of the retinal vascular network, combined with a persistent low-grade inflammation that leads to vision-threatening complications. Netrin-4 (NTN4) is a laminin-related secreted protein and guidance
Externí odkaz:
https://doaj.org/article/cb78aaf66915468fb3ddfcc339d1ac29
Autor:
Sergio Crespo-Garcia, Nadine Reichhart, Sergej Skosyrski, Marco Foddis, Jim Wu, Aleksandar Figura, Christina Herrspiegel, Martina Füchtemeier, Celeste Sassi, Ulrich Dirnagl, Antonia M Joussen, Olaf Strauss
Publikováno v:
PLoS ONE, Vol 13, Iss 3, p e0193961 (2018)
Animal models of disease are an indispensable element in our quest to understand pathophysiology and develop novel therapies. Ex vivo studies have severe limitations, in particular their inability to study individual disease progression over time. In
Externí odkaz:
https://doaj.org/article/ef8ea560066a42d2b20ec2b9adb337f8
Autor:
Sergio Crespo-Garcia, Nadine Reichhart, Sergej Skosyrski, Marco Foddis, Jim Wu, Aleksandar Figura, Christina Herrspiegel, Martina Füchtemeier, Celeste Sassi, Ulrich Dirnagl, Antonia M Joussen, Olaf Strauss
Publikováno v:
PLoS ONE, Vol 13, Iss 4, p e0196538 (2018)
[This corrects the article DOI: 10.1371/journal.pone.0193961.].
Externí odkaz:
https://doaj.org/article/e3f360d744c8431a926e892d19f20592
Autor:
Masayuki Hata, Elisabeth M. M. A. Andriessen, Maki Hata, Roberto Diaz-Marin, Frédérik Fournier, Sergio Crespo-Garcia, Guillaume Blot, Rachel Juneau, Frédérique Pilon, Agnieszka Dejda, Vera Guber, Emilie Heckel, Caroline Daneault, Virginie Calderon, Christine Des Rosiers, Heather J. Melichar, Thomas Langmann, Jean-Sebastien Joyal, Ariel M. Wilson, Przemyslaw Sapieha
Publikováno v:
Science (New York, N.Y.). 379(6627)
Age-related macular degeneration is a prevalent neuroinflammatory condition and a major cause of blindness driven by genetic and environmental factors such as obesity. In diseases of aging, modifiable factors can be compounded over the life span. We