Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Sergio Casas-Tintò"'
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S550- (2023)
Externí odkaz:
https://doaj.org/article/5219d665b49941c29d40af1844fa31e8
Autor:
María García-García, Sara Sánchez-Perales, Patricia Jarabo, Enrique Calvo, Trevor Huyton, Liran Fu, Sheung Chun Ng, Laura Sotodosos-Alonso, Jesús Vázquez, Sergio Casas-Tintó, Dirk Görlich, Asier Echarri, Miguel A. Del Pozo
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-21 (2022)
The translation of mechanical cues into gene expression changes is dependent on the nuclear import of mechanoresponsive transcriptional regulators. Here the authors identify that Importin-7 drives the nuclear import of one such regulator YAP while YA
Externí odkaz:
https://doaj.org/article/7cb59e3af2ed46b8b24506a9c27680be
Publikováno v:
PLoS Genetics, Vol 18, Iss 7, p e1010329 (2022)
Glioblastoma (GB) is the most aggressive, lethal and frequent primary brain tumor. It originates from glial cells and is characterized by rapid expansion through infiltration. GB cells interact with the microenvironment and healthy surrounding tissue
Externí odkaz:
https://doaj.org/article/1cf9643a6c66476dba70cec1783c64df
Autor:
Marta Portela, Sergio Casas-Tintó
Publikováno v:
Neuroscience Insights, Vol 15 (2020)
Gliomas are brain tumors originated from glial cells. The most frequent form of glioma is the glioblastoma (GB). This lethal tumor is frequently originated from genetic alterations in epidermal growth factor receptor (EGFR) and PI3K pathways. Recent
Externí odkaz:
https://doaj.org/article/0861072a5d8540eba33de304ad568cca
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 4, p 2043 (2022)
Glioblastoma (GB) is the most frequent malignant brain tumor among adults and currently there is no effective treatment. This aggressive tumor grows fast and spreads through the brain causing death in 15 months. GB cells display a high mutation rate
Externí odkaz:
https://doaj.org/article/c7611ebeee63478785d48ba57420ee0d
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0184238 (2017)
The number of synapses is a major determinant of behavior and many neural diseases exhibit deviations in that number. However, how signaling pathways control this number is still poorly understood. Using the Drosophila larval neuromuscular junction,
Externí odkaz:
https://doaj.org/article/1101801905e74f838b76aa7793e99529
Publikováno v:
Royal Society Open Science, Vol 4, Iss 3 (2017)
In Drosophila melanogaster the most widely used technique to drive gene expression is the binary UAS/Gal4 system. We show here that a set of nervous system specific enhancers (elav, D42/Toll-6, OK6/RapGAP1) display ectopic activity in epithelial tiss
Externí odkaz:
https://doaj.org/article/f6e1bfcf98114ffe81aa70256d0c2257
Autor:
Sergio Casas-Tintó, Marta Portela
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 22, p 5641 (2019)
Increasing evidence during the past two decades shows that cells interconnect and communicate through cytonemes. These cytoskeleton-driven extensions of specialized membrane territories are involved in cell−cell signaling in development, patterning
Externí odkaz:
https://doaj.org/article/51f6ffe11b4843fea03fc1015bfb4c5a
Publikováno v:
Cell Reports, Vol 2, Iss 3, Pp 526-539 (2012)
Cell competition is a mechanism that eliminates slow dividing cells from a growing population. It is believed that the genes wasp, psr, and draper are active in the cells that win the competition (“winner cells”) and that they are essential in th
Externí odkaz:
https://doaj.org/article/2a98337ff03947d781ff0be9829b966e
Publikováno v:
mBio, Vol 6, Iss 2 (2015)
ABSTRACT Upon infection, pathogen recognition leads to a rapidly activated gene expression program that induces antimicrobial effectors to clear the invader. We recently found that Nup98 regulates the expression of a subset of rapidly activated antiv
Externí odkaz:
https://doaj.org/article/0116e6d954844afca527d8d29a1d043c