Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Sergio Bacchi"'
Autor:
Sergio Bacchi
Publikováno v:
Revista Fim do Mundo, Vol 1, Iss 01 (2020)
Evolução do capitalismo e salto qualitativo nos fundamentos da Revolução Industrial; a máquina e seus órgãos; o surgimento do quarto órgão da máquina, o órgão de controle; consequências históricas após o seu surgimento; a nova etapa hi
Externí odkaz:
https://doaj.org/article/e30da20653e9434a9ffb55134cea3853
Autor:
Sergio Bacchi Machado
Publikováno v:
Biblioteca Digital de Teses e Dissertações da USPUniversidade de São PauloUSP.
Partindo de uma abordagem da figura polêmica da loucura como domínio estratégico de inúmeras relações de poder que não majoritariamente orientadas por princípios restritivos, esta dissertação enfoca a produção do sujeito usuário em u
Autor:
Machado, Sergio Bacchi
Partindo de uma abordagem da figura polêmica da loucura como domínio estratégico de inúmeras relações de poder que não majoritariamente orientadas por princípios restritivos, esta dissertação enfoca a produção do sujeito usuário" em um
Publikováno v:
Tetrahedron Letters. 53:1878-1881
Organocatalytic asymmetric Michael addition of 3-(OTBS)-propanal to β-nitrostyrenes catalyzed by chiral sulfamides was investigated. Good d.r. (up to 80:20) and excellent enantioselectivities (up to >99% ee) were achieved. Both the N -[(1 R ,2 R )-2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::47f0ca916b86a63412edfed6134d1599
https://doi.org/10.1016/j.tetlet.2012.01.072
https://doi.org/10.1016/j.tetlet.2012.01.072
Publikováno v:
Organic Process Research & Development. 15:1388-1391
During the development of new active pharmaceutical ingredients (API), the control of low level impurities plays a crucial role in the progression of a new compound. Particular attention is given to known or suspected genotoxic impurities, which, to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c56e6ff3e87acb48963b4b8354cab967
https://doi.org/10.1021/op200203t
https://doi.org/10.1021/op200203t
Autor:
Federico Scaravelli, Laura Panelli, Federica Stazi, Pieter Westerduin, Luca Massari, Sergio Bacchi, William Maton, Mark J. Hughes
Publikováno v:
Organic Process Research & Development. 14:1364-1372
A novel series of 1,2,4-triazol-3-yl-azabicyclo[3.1.0]hexanes was recently identified as new highly potent and selective dopamine (DA) D3 receptor antagonists. This class of molecules deserved the Chemical Development special attention to quantify th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef78ccbdc54567c6f4cb5580990fb21b
https://doi.org/10.1021/op100176u
https://doi.org/10.1021/op100176u
Autor:
Federica Stazi, Pieter Westerduin, Damiano Castoldi, Sergio Bacchi, Ornella Curcuruto, William Maton
Publikováno v:
Synthesis. 2010:3332-3338
Various approaches to [2-fluoro-4-(trifluoromethyl)phenyl]acetonitrile were investigated. Two of these methods were selected and applied to a variety of electron-deficient substrates, thereby expanding the scopes of the procedures.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::94c34a52cea5252b20592c9145edc522
https://doi.org/10.1055/s-0030-1257871
https://doi.org/10.1055/s-0030-1257871
Autor:
Angelo M. Manzo, Arianna Ribecai, Stefano Provera, Sara Rossi, Monica Delpogetto, Simone Guelfi, Pieter Westerduin, Marie Hourdin, Alcide Perboni, Sergio Bacchi, Lucilla Turco, Paolo Stabile
Publikováno v:
Organic Process Research & Development. 14:895-901
A case study on the synthesis of novel CRF-1 antagonists containing the 2,3-dihydro-1H-pyrrolo[2,3-b]pyridine moiety is presented. The development of ever more efficient synthetic routes allowed th...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::57f8ffcccb3566e72760c84047875f68
https://doi.org/10.1021/op100147h
https://doi.org/10.1021/op100147h
Autor:
Maria Concepción Cerrato Oliveros, Sergio Bacchi, Antonella Carangio, Mohammad Yahyah, Arianna Ribecai
Publikováno v:
Organic Process Research & Development. 14:332-338
Classical experimental designs have been used as configurations of choice at GlaxoSmithKline within Chemical Development in establishing robust products and processes while achieving other goals such as reduction of cost, waste, process investigation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb8df12b0f0640e0a569f3dd33c19de6
https://doi.org/10.1021/op900286r
https://doi.org/10.1021/op900286r
Autor:
Corinne Leroi, Zadeo Cimarosti, Stefano Provera, Michael David Goodyear, Giuseppe Guercio, Marie Hourdin, Francesco Tinazzi, Ilaria Bientinesi, Alcide Perboni, Sergio Bacchi, Stefano Curti
Publikováno v:
Organic Process Research & Development. 13:1100-1110
GW597599 1 is a novel NK-1 antagonist currently under investigation for the treatment of central nervous system disorders and emesis. The initial chemical development synthetic route, derived from the one used by medicinal chemistry, involved several
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::158b1f3c2b768396431325a7047235d2
https://doi.org/10.1021/op9002032
https://doi.org/10.1021/op9002032