Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Sergio Andreu-Sánchez"'
Autor:
Jiafei Wu, Victoria Palasantzas, Sergio Andreu-Sánchez, Torsten Plösch, Sam Leonard, Shuang Li, Marc Jan Bonder, Harm-Jan Westra, Joyce van Meurs, Mohsen Ghanbari, Lude Franke, Alexandra Zhernakova, Jingyuan Fu, Joanne A. Hoogerland, Daria V. Zhernakova
Publikováno v:
Clinical Epigenetics, Vol 16, Iss 1, Pp 1-16 (2024)
Abstract Background The plasma metabolome reflects the physiological state of various biological processes and can serve as a proxy for disease risk. Plasma metabolite variation, influenced by genetic and epigenetic mechanisms, can also affect the ce
Externí odkaz:
https://doaj.org/article/9ba2686e25cc4689806e48f764522f07
Autor:
Sanzhima Garmaeva, Trishla Sinha, Anastasia Gulyaeva, Nataliia Kuzub, Johanne E. Spreckels, Sergio Andreu-Sánchez, Ranko Gacesa, Arnau Vich Vila, Siobhan Brushett, Marloes Kruk, Lifelines NEXT cohort study, Jackie Dekens, Jan Sikkema, Folkert Kuipers, Andrey N. Shkoporov, Colin Hill, Sicco Scherjon, Cisca Wijmenga, Jingyuan Fu, Alexander Kurilshikov, Alexandra Zhernakova
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Early development of the gut ecosystem is crucial for lifelong health. While infant gut bacterial communities have been studied extensively, the infant gut virome remains under-explored. To study the development of the infant gut virome over
Externí odkaz:
https://doaj.org/article/13d353f413e44ed2b76d4e0acac1dbd0
Autor:
Sergio Andreu-Sánchez, Aida Ripoll-Cladellas, Anna Culinscaia, Ozlem Bulut, Arno R. Bourgonje, Mihai G. Netea, Peter Lansdorp, Geraldine Aubert, Marc Jan Bonder, Lude Franke, Thomas Vogl, Monique G.P. van der Wijst, Marta Melé, Debbie Van Baarle, Jingyuan Fu, Alexandra Zhernakova
Publikováno v:
iScience, Vol 27, Iss 6, Pp 109981- (2024)
Summary: Encounters with pathogens and other molecules can imprint long-lasting effects on our immune system, influencing future physiological outcomes. Given the wide range of microbes to which humans are exposed, their collective impact on health i
Externí odkaz:
https://doaj.org/article/a625eed26ff74ff68e49a04b0978d288
Autor:
Sergio Andreu‐Sánchez, Shahzad Ahmad, Alexander Kurilshikov, Marian Beekman, Mohsen Ghanbari, Martijn vanFaassen, Inge C. L. van denMunckhof, Marinka Steur, Amy Harms, Thomas Hankemeier, M. Arfan Ikram, Maryam Kavousi, Trudy Voortman, Robert Kraaij, Mihai G. Netea, Joost H. W. Rutten, Niels P. Riksen, Alexandra Zhernakova, Folkert Kuipers, P. Eline Slagboom, Cornelia M. vanDuijn, Jingyuan Fu, Dina Vojinovic
Publikováno v:
iMeta, Vol 3, Iss 3, Pp n/a-n/a (2024)
Abstract Trimethylamine N‐oxide (TMAO) is a circulating microbiome‐derived metabolite implicated in the development of atherosclerosis and cardiovascular disease (CVD). We investigated whether plasma levels of TMAO, its precursors (betaine, carni
Externí odkaz:
https://doaj.org/article/8f4a85a05abd4322a6397015b41442e1
Autor:
Asier Fernández-Pato, Trishla Sinha, Ranko Gacesa, Sergio Andreu-Sánchez, Milla F. Brandao Gois, Jody Gelderloos-Arends, Dianne B. H. Jansen, Marloes Kruk, Martin Jaeger, Leo A. B. Joosten, Mihai G. Netea, Rinse K. Weersma, Cisca Wijmenga, Hermie J. M. Harmsen, Jingyuan Fu, Alexandra Zhernakova, Alexander Kurilshikov
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract The lack of standardization in the methods of DNA extraction from fecal samples represents the major source of experimental variation in the microbiome research field. In this study, we aimed to compare the metagenomic profiles and microbiom
Externí odkaz:
https://doaj.org/article/52385fca2f7241a7beafe6bc3f4fd066
Autor:
Martijn Vochteloo, Patrick Deelen, Britt Vink, BIOS Consortium, Ellen A. Tsai, Heiko Runz, Sergio Andreu-Sánchez, Jingyuan Fu, Alexandra Zhernakova, Harm-Jan Westra, Lude Franke
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-26 (2024)
Abstract Expression quantitative trait loci (eQTL) offer insights into the regulatory mechanisms of trait-associated variants, but their effects often rely on contexts that are unknown or unmeasured. We introduce PICALO, a method for hidden variable
Externí odkaz:
https://doaj.org/article/1bb030c23f7a471a97ee8771da5fe1e3
Autor:
Yue Zhang, Sergio Andreu-Sánchez, Nadira Vadaq, Daoming Wang, Vasiliki Matzaraki, Wouter A. van der Heijden, Ranko Gacesa, Rinse K. Weersma, Alexandra Zhernakova, Linos Vandekerckhove, Quirijn de Mast, Leo A. B. Joosten, Mihai G. Netea, André J. A. M. van der Ven, Jingyuan Fu
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)
BackgroundPeople living with human immunodeficiency virus (PLHIV) are exposed to chronic immune dysregulation, even when virus replication is suppressed by antiretroviral therapy (ART). Given the emerging role of the gut microbiome in immunity, we hy
Externí odkaz:
https://doaj.org/article/95e0698f27d345e292c73b1565aa8964
Autor:
Sergio Andreu-Sánchez, Geraldine Aubert, Aida Ripoll-Cladellas, Sandra Henkelman, Daria V. Zhernakova, Trishla Sinha, Alexander Kurilshikov, Maria Carmen Cenit, Marc Jan Bonder, Lude Franke, Cisca Wijmenga, Jingyuan Fu, Monique G. P. van der Wijst, Marta Melé, Peter Lansdorp, Alexandra Zhernakova
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-14 (2022)
Deep molecular and phenotypic data highlights the links of human telomere lengths from six different blood cells with genetics, parental phenotypes mediated by epigenetic signals and expression changes at the single cell level.
Externí odkaz:
https://doaj.org/article/0a00c1e07f114ae59b1c44d8c5c72806
Publikováno v:
iMeta, Vol 2, Iss 2, Pp n/a-n/a (2023)
Externí odkaz:
https://doaj.org/article/02011bc6747b4cd6925ef308ed26dfac
Autor:
Sergio Andreu-Sánchez, Lianmin Chen, Daoming Wang, Hannah E. Augustijn, Alexandra Zhernakova, Jingyuan Fu
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Microbes live in complex communities that are of major importance for environmental ecology, public health, and animal physiology and pathology. Short-read metagenomic shotgun sequencing is currently the state-of-the-art technique for exploring these
Externí odkaz:
https://doaj.org/article/ad4bd3b00a38420db934ed0363067cf1