Zobrazeno 1 - 10
of 259
pro vyhledávání: '"Sergio A Quezada"'
Autor:
Hugh O'Brien, Max Salm, Laura T Morton, Maciej Szukszto, Felix O'Farrell, Charlotte Boulton, Laurence King, Supreet Kaur Bola, Pablo D Becker, Andrew Craig, Morten Nielsen, Yardena Samuels, Charles Swanton, Marc R Mansour, Sine Reker Hadrup, Sergio A Quezada
Publikováno v:
PLoS Computational Biology, Vol 20, Iss 11, p e1012511 (2024)
Neoantigen immunogenicity prediction is a highly challenging problem in the development of personalised medicines. Low reactivity rates in called neoantigens result in a difficult prediction scenario with limited training datasets. Here we describe I
Externí odkaz:
https://doaj.org/article/d0648697accf4d3db851dc1ee5b36eb3
Autor:
Andrew Craig, Martin Forster, Samra Turajlic, Sergio A Quezada, Katy Newton, Karl Peggs, Fong Chan, Karen Matthews, Theres Oakes, Gareth Wilson, Elizabeth Larose Cadieux, Max Salm, Hugh O’Brien
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/e8e734fff40a4ec7ba5a3f66dcf9a8fb
Autor:
Sergio A Quezada, Katy Newton, Monica Sassi, Sandro Gomez, Evi Rologi, Meghan Madigan, Joanne Tang, Sarah Thirkell, Samuel Jide Banwo, Temi Ogunleye, Sophie McKeeman, Claire Law, Unnaamalai Meyyappan, Eleni Kotsiou, Theres Oakes, Miha Kosmac, Luke Goodsell, Connor Carolan, Justin Ahern, Tim Hillyer, Bongi Ndlovu, Henrieta Fraser, Edward Samuel
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/2fa7341761a1438180b489957f79053c
Autor:
Giorgia Fanelli, Marco Romano, Estefania Nova-Lamperti, Mariana Werner Sunderland, Alessandra Nerviani, Cristiano Scottà, Michele Bombardieri, Sergio A Quezada, Steven H Sacks, Randolph J Noelle, Costantino Pitzalis, Robert I Lechler, Giovanna Lombardi, Pablo D Becker
Publikováno v:
PLoS Biology, Vol 19, Iss 4, p e3001199 (2021)
Programmed cell death protein 1 (PD-1) is expressed on T cells upon T cell receptor (TCR) stimulation. PD-1 ligand 1 (PD-L1) is expressed in most tumor environments, and its binding to PD-1 on T cells drives them to apoptosis or into a regulatory phe
Externí odkaz:
https://doaj.org/article/3fbd2067f1594e26aba21fe040a73129
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
As part of the 2019 Immunotherapy Bridge congress (December 4–5, Naples, Italy), the Great Debate session featured counterpoint views from leading experts on six topical issues in immunotherapy today. These were the use of chimeric antigen receptor
Externí odkaz:
https://doaj.org/article/f159b1b615c54c22ad0cfb29a9b81a27
Autor:
Paolo A. Ascierto, Sanjiv S. Agarwala, Christian Blank, Corrado Caracò, Richard D. Carvajal, Marc S. Ernstoff, Soldano Ferrone, Bernard A. Fox, Thomas F. Gajewski, Claus Garbe, Jean-Jacques Grob, Omid Hamid, Michelle Krogsgaard, Roger S. Lo, Amanda W. Lund, Gabriele Madonna, Olivier Michielin, Bart Neyns, Iman Osman, Solange Peters, Poulikos I. Poulikakos, Sergio A. Quezada, Bradley Reinfeld, Laurence Zitvogel, Igor Puzanov, Magdalena Thurin
Publikováno v:
Journal of Translational Medicine, Vol 20, Iss 1, Pp 1-21 (2022)
Abstract Advances in immune checkpoint and combination therapy have led to improvement in overall survival for patients with advanced melanoma. Improved understanding of the tumor, tumor microenvironment and tumor immune-evasion mechanisms has result
Externí odkaz:
https://doaj.org/article/eceaa54ada8b4252a49fcbe967456d2a
Autor:
Simon P. Castillo, Felipe Galvez-Cancino, Jiali Liu, Steven M. Pollard, Sergio A. Quezada, Yinyin Yuan
Publikováno v:
Seminars in Cancer Biology. 92:139-149
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a7832c3c13d8f743aef03dcf3862385
https://doi.org/10.1016/j.semcancer.2023.04.004
https://doi.org/10.1016/j.semcancer.2023.04.004
Autor:
James Monypenny, Hanna Milewicz, Fabian Flores-Borja, Gregory Weitsman, Anthony Cheung, Ruhe Chowdhury, Thomas Burgoyne, Appitha Arulappu, Katherine Lawler, Paul R. Barber, Jose M. Vicencio, Melanie Keppler, Wahyu Wulaningsih, Sean M. Davidson, Franca Fraternali, Natalie Woodman, Mark Turmaine, Cheryl Gillett, Dafne Franz, Sergio A. Quezada, Clare E. Futter, Alex Von Kriegsheim, Walter Kolch, Borivoj Vojnovic, Jeremy G. Carlton, Tony Ng
Publikováno v:
Cell Reports, Vol 24, Iss 3, Pp 630-641 (2018)
Summary: The immunosuppressive transmembrane protein PD-L1 was shown to traffic via the multivesicular body (MVB) and to be released on exosomes. A high-content siRNA screen identified the endosomal sorting complexes required for transport (ESCRT)-as
Externí odkaz:
https://doaj.org/article/271d76a1d4d644ff8f8a80c533ecdc3e
Autor:
Sam M. Janes, Nicholas McGranahan, Sergio A. Quezada, Yinyin Yuan, Teresa Marafioti, Peter J. Campbell, Christina Thirlwell, Charles Swanton, Jeremy George, Ricky M. Thakrar, Lisa M. Coussens, Courtney Betts, William Larson, Marie-Liesse Asselin-Labat, Claire Marceaux, Bernadette Carroll, Andrew J. Furness, Pascal F. Durrenberger, Sophia Antoniou, David A. Moore, Mary Falzon, Celine Denais, Yeman B. Hagos, Fraser R. Millar, Jake Y. Henry, Kate H.C. Gowers, Robert E. Hynds, Henry Lee-Six, Christodoulos P. Pipinikas, Deepak P. Chandrasekharan, Lukas Kalinke, Rachel Rosenthal, Ayse U. Akarca, Tom Lund, Shan E. Ahmed Raza, Khalid AbdulJabbar, Vitor H. Teixeira, Adam Pennycuick
Immune cell deconvolution from molecular data. Relative proportions of immune cell subtypes are predicted from gene expression data using the Danaher method, and from methylation data using methylCIBERSORT. Differences between progressive and regress
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0408e249465611db42368906c8f88642
https://doi.org/10.1158/2159-8290.22536935.v1
https://doi.org/10.1158/2159-8290.22536935.v1
Autor:
Sam M. Janes, Nicholas McGranahan, Sergio A. Quezada, Yinyin Yuan, Teresa Marafioti, Peter J. Campbell, Christina Thirlwell, Charles Swanton, Jeremy George, Ricky M. Thakrar, Lisa M. Coussens, Courtney Betts, William Larson, Marie-Liesse Asselin-Labat, Claire Marceaux, Bernadette Carroll, Andrew J. Furness, Pascal F. Durrenberger, Sophia Antoniou, David A. Moore, Mary Falzon, Celine Denais, Yeman B. Hagos, Fraser R. Millar, Jake Y. Henry, Kate H.C. Gowers, Robert E. Hynds, Henry Lee-Six, Christodoulos P. Pipinikas, Deepak P. Chandrasekharan, Lukas Kalinke, Rachel Rosenthal, Ayse U. Akarca, Tom Lund, Shan E. Ahmed Raza, Khalid AbdulJabbar, Vitor H. Teixeira, Adam Pennycuick
Supplementary Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c889c181198e05bf5aa948da6e69f5d
https://doi.org/10.1158/2159-8290.22536944.v1
https://doi.org/10.1158/2159-8290.22536944.v1