Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Sergio, Cafaggi"'
Autor:
Carla Fenoglio, Anna Aprile, Marta Rossi, Michele Cilli, Sergio Cafaggi, Pierluigi Santi, Mattia Rocco, Aldo Profumo, Maurizio Viale, Eleonora Russo
Publikováno v:
Investigational New Drugs. 33:1151-1161
Fibrin gels are attractive biomaterials for local delivery of a variety of agents, from drugs to proteins. Similarly, polymer-anticancer-drug conjugates and nanoparticles are emerging as potential candidates for cancer treatment. Combining these diff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0453ce1b25de648c0307c90490c5b84
https://doi.org/10.1007/s10637-015-0291-x
https://doi.org/10.1007/s10637-015-0291-x
Autor:
Gabriele Caviglioli, Greta Sillo, Brunella Parodi, Sergio Cafaggi, Rossana Stefani, Eleonora Russo, Angela Bisio, Maurizio Viale, Cinzia Aiello
Publikováno v:
Investigational New Drugs. 29:443-455
In this work, nanoparticles with a positive surface charge were prepared through the electrostatic interaction of a new cisplatin-hyaluronate complex with N-trimethyl chitosan (substitution degree of 85%). Mean particle diameter was approximately 195
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3918f8d8b08577b3991c0ce48988eb1b
https://doi.org/10.1007/s10637-009-9373-y
https://doi.org/10.1007/s10637-009-9373-y
Autor:
Brunella Parodi, Gabriele Caviglioli, Gaetano Bignardi, Eleonora Russo, Sergio Cafaggi, Riccardo Leardi
Publikováno v:
Journal of Controlled Release. 102:159-169
The aim of this work was to prepare and evaluate a matrix for buccal drug delivery composed of a chitosan salt and poloxamer 407. Different chitosan salts were formed by reacting chitosan with acetic, citric, and lactic acid. Various proportions of p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::266ff25e14b1613b444df3fc12aea16c
https://doi.org/10.1016/j.jconrel.2004.09.019
https://doi.org/10.1016/j.jconrel.2004.09.019
Publikováno v:
Chemometrics and Intelligent Laboratory Systems. 65:139-147
The aim of this tutorial is to show the application of a mixture experimental design to a problem of pharmaceutical formulation. A gel, based on poloxamer 407, useful for topical administration of tolfenamic acid, a potent anti-inflammatory drug very
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da50e2ae5950f701f2a28afc2ad96907
https://doi.org/10.1016/s0169-7439(02)00045-x
https://doi.org/10.1016/s0169-7439(02)00045-x
Autor:
Massimo Ottone, Antonio Zicca, Maria A. Mariggiò, Vittorio Bocchini, Maurizio Viale, Maria O. Vannozzi, Gabriele Caviglioli, Sergio Cafaggi
Publikováno v:
European Journal of Pharmacology. 442:265-272
In preceding papers, we proposed that procainamide hydrochloride, a class I antiarrhythmic agent, was able to protect mice and rats from cisplatin-induced nephrotoxicity and that it could exert its action through accumulation in kidneys followed by c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88c102cda6b85c5a70d7a6ca00df4de2
https://doi.org/10.1016/s0014-2999(02)01537-6
https://doi.org/10.1016/s0014-2999(02)01537-6
Autor:
Eleonora Russo, Gabriele Caviglioli, Valeria Cagno, David Lembo, Noemi Gaglianone, C. Zibana, Manuela Donalisio, Sara Baldassari, Brunella Parodi, Sergio Cafaggi
A new nanoparticulate system for foscarnet delivery was prepared and evaluated. Nanoparticles were obtained by ionotropic gelation of chitosan induced by foscarnet itself, acting as an ionotropic agent in a manner similar to tripolyphosphate anion. A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::312c022f2f1a6cb3339b5f9849cc98b0
http://hdl.handle.net/11567/697977
http://hdl.handle.net/11567/697977
Autor:
Maurizio Viale, Sergio Cafaggi, Maria A. Mariggiò, Mauro Esposito, Ilaria Pastrone, Arianna Parodi
Publikováno v:
Investigational New Drugs. 16:297-302
We evaluated in vitro the antiproliferative activity of DPR (Fig. 1), a new cisplatin-derived compound, in combination with five conventional anticancer drugs: the antimetabolites 5-fluorouracil (5FU) and methotrexate (MTX), the alkylating agent mito
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7a44e49cd7ac639957c2049efe6238b
https://doi.org/10.1023/a:1006228027066
https://doi.org/10.1023/a:1006228027066
Autor:
Sara Baldassari, Eleonora Russo, Sergio Cafaggi, Noemi Gaglianone, Brunella Parodi, Gabriele Caviglioli, Anna Maria Schito
A matrix based on chitosan lactate and poloxamer 407 was evaluated as a delivery system for the vaginal administration of the antifungal drug econazole. The matrix was investigated both containing the pure drug and after introducing microparticles of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59b7693c8007cec8050404ca6a04b165
http://hdl.handle.net/11567/747389
http://hdl.handle.net/11567/747389
Autor:
M. Viale, Maria O. Vannozzi, Brunella Parodi, Franco Merlo, Sergio Cafaggi, Maria Teresa Esposito
Publikováno v:
European Journal of Cancer. 32:2327-2333
The administration of combinations of platinum compounds is considered as a useful alternative therapeutic strategy to avoid the complications of toxic events during cancer chemotherapy in order to obtain a therapeutic advantage. On the basis of prev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc3c37bd75b3fb97905b4c04ed97fe5b
https://doi.org/10.1016/s0959-8049(96)00354-1
https://doi.org/10.1016/s0959-8049(96)00354-1
Publikováno v:
Cancer Chemotherapy and Pharmacology. 35:371-376
The emergence of drug resistance during tumor chemotherapy is one of the main problems associated with cancer treatment, particularly with cisplatin (cis-DDP). In the hope of overcoming this problem, various cis-DDP-derived compounds have been synthe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e026460f1373460a49f2256995fed33
https://doi.org/10.1007/s002800050249
https://doi.org/10.1007/s002800050249