Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Sergi Rodríguez-Escrich"'
Autor:
Ariadna Fernández, Enrique Portillo-Salido, Mónica Porras, Adriana Lorente, José Miguel Vela, Carmen Almansa, Raquel Enrech, J.L. Diaz, Begoña Fernández, Albert Dordal, Sergi Rodríguez-Escrich, Raquel F. Reinoso, Mónica García
Publikováno v:
ACS Med Chem Lett
[Image: see text] The synthesis and pharmacological activities of a new series of piperazinyl quinazolin-4-(3H)-one derivatives acting toward the α2δ-1 subunit of voltage-gated calcium channels (Ca(v)α2δ-1) are reported. Different positions of a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::185ebf310cb9bbc8e97f822502f72c2b
https://doi.org/10.1021/acsmedchemlett.1c00416
https://doi.org/10.1021/acsmedchemlett.1c00416
Autor:
Magda Bordas, Virginia Llorente, Javier Burgueño, Enrique Portillo-Salido, Begoña Fernández, Mónica García, Carmen Almansa, Marta Pujol, Sergi Rodríguez-Escrich, Lourdes Garriga, Georgia Gris, Albert Dordal, Eva Ayet, Ute Christmann, Marina Virgili, José Miguel Vela
Publikováno v:
Journal of Medicinal Chemistry. 64:10139-10154
A new series of propionamide derivatives was developed as dual μ-opioid receptor agonists and σ1 receptor antagonists. Modification of a high-throughput screening hit originated a series of piperazinylcycloalkylmethyl propionamides, which were expl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6283a8192c91d9c5578b53eb7b1cb388
https://doi.org/10.1021/acs.jmedchem.1c00417
https://doi.org/10.1021/acs.jmedchem.1c00417
Autor:
Mónica, García, Virginia, Llorente, Lourdes, Garriga, Ute, Christmann, Sergi, Rodríguez-Escrich, Marina, Virgili, Begoña, Fernández, Magda, Bordas, Eva, Ayet, Javier, Burgueño, Marta, Pujol, Albert, Dordal, Enrique, Portillo-Salido, Georgia, Gris, José Miguel, Vela, Carmen, Almansa
Publikováno v:
Journal of medicinal chemistry. 64(14)
A new series of propionamide derivatives was developed as dual μ-opioid receptor agonists and σ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::55020aa55f57caec684d484acdf8ccbd
https://pubmed.ncbi.nlm.nih.gov/34236190
https://pubmed.ncbi.nlm.nih.gov/34236190
Autor:
Carles Rodríguez-Escrich, Ciril Jimeno, Miquel A. Pericàs, Lluis Sola, Sergi Rodríguez-Escrich
Publikováno v:
Advanced Synthesis & Catalysis. 350:2250-2260
A series of enantiopure ligands based on the aminoindanol scaffold, but differing in regio- and stereochemistry has been synthesized. These ligands have been conveniently derivatized and their catalytic efficiency in different enantioselective reacti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::35786b35762973af4a0fc7a146a43f16
https://doi.org/10.1002/adsc.200800420
https://doi.org/10.1002/adsc.200800420
Autor:
Lluis Sola, Miquel A. Pericàs, Sergi Rodríguez-Escrich, Katamreddy Subba Reddy, Anton Vidal-Ferran, Gisela Colet, Carles Rodríguez-Escrich, Ciril Jimeno
Publikováno v:
ChemInform. 39
The structural optimization of a family of modular, enantiopure β-amino alcohol ligands with a common 2-amino-2-aryl-1,1-diphenylethanol skeleton, whose stereogenicity was introduced through the Jacobsen epoxidation of 1,1-diphenyl-2-arylethylenes,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a83f169e9ebfc59546ad2daa4e86bfb
https://doi.org/10.1002/chin.200849067
https://doi.org/10.1002/chin.200849067
Autor:
Anton Vidal-Ferran, Lluis Sola, Ciril Jimeno, Gisela Colet, Katamreddy Subba Reddy, Carles Rodríguez-Escrich, Sergi Rodríguez-Escrich, Miquel A. Pericàs
Publikováno v:
The Journal of organic chemistry. 73(14)
The structural optimization of a family of modular, enantiopure beta-amino alcohol ligands with a common 2-amino-2-aryl-1,1-diphenylethanol skeleton, whose stereogenicity was introduced through the Jacobsen epoxidation of 1,1-diphenyl-2-arylethylenes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c81372d5efaf4efa145a9b3ba3a02b7
https://pubmed.ncbi.nlm.nih.gov/18549280
https://pubmed.ncbi.nlm.nih.gov/18549280
Publikováno v:
ChemInform. 37
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bfcadc2f2cd78c40e73c7a3cf4362c21
https://doi.org/10.1002/chin.200601087
https://doi.org/10.1002/chin.200601087
(S)-2-[(R)-Fluoro(phenyl)methyl]oxirane: A General Reagent for Determining the ee of α-Chiral Amines
Publikováno v:
Organic Letters. 12:3116-3116
(S)-2-[(R)-Fluoro(phenyl)methyl]oxirane is a new, synthetic, yet enantiopure, chiral resolution reagent, readily obtained from enantiopure (2S,3S)-phenylglycidol, that reacts with a variety of alpha-chiral primary and secondary amines in a straightfo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f6c3878637013113fb1b168b95f74b0
https://doi.org/10.1021/ol1008735
https://doi.org/10.1021/ol1008735