Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Sergi Roda"'
Publikováno v:
Eng, Vol 5, Iss 1, Pp 91-103 (2024)
Protein engineering is the design and modification of protein structures to optimize their functions or create novel functionalities for applications in biotechnology, medicine or industry. It represents an essential scientific solution for many of t
Externí odkaz:
https://doaj.org/article/918843479472405ba371b252b1f1705c
Autor:
Paula Vidal, Mónica Martínez-Martínez, Laura Fernandez-Lopez, Sergi Roda, Celia Méndez-García, Olga V. Golyshina, Víctor Guallar, Ana I. Peláez, Manuel Ferrer
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Acid mine drainage (AMD) systems are extremely acidic and are metal-rich formations inhabited by relatively low-complexity communities of acidophiles whose enzymes remain mostly uncharacterized. Indeed, enzymes from only a few AMD sites have been stu
Externí odkaz:
https://doaj.org/article/76e835d9a207434ba220ff65422d8c2f
Autor:
Xiaomin Xu, Jacob M. A. van Hengst, Yejia Mao, Mireia Martinez, Sergi Roda, Martin Floor, Victor Guallar, Caroline E. Paul, Miguel Alcalde, Frank Hollmann
Publikováno v:
Angewandte Chemie (International Edition), 62(24)
A peroxygenase-catalysed hydroxylation of organosilanes is reported. The recombinant peroxygenase from Agrocybe aegerita (AaeUPO) enabled efficient conversion of a broad range of silane starting materials in attractive productivities (up to 300 mM h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8da9055679172579254bcc97a0dbeef2
https://doi.org/10.1002/ange.202302844
https://doi.org/10.1002/ange.202302844
Autor:
Laura Fernandez-Lopez, Sergi Roda, Jose L. Gonzalez-Alfonso, Francisco J. Plou, Víctor Guallar, Manuel Ferrer
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 21; Pages: 13337
[EN] Proteases are abundant in prokaryotic genomes (~10 per genome), but their recovery encounters expression problems, as only 1% can be produced at high levels; this value differs from that of similarly abundant esterases (1–15 per genome), 50% o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f89bd142057e0ec6f4a647d9bbf54927
http://hdl.handle.net/10261/296362
http://hdl.handle.net/10261/296362
Autor:
Manuel Ferrer, Victor Guallar, Gerard Santiago, Laura Fernandez-Lopez, Rubén Cañadas, Sergi Roda
Publikováno v:
UPCommons. Portal del coneixement obert de la UPC
Universitat Politècnica de Catalunya (UPC)
Universitat Politècnica de Catalunya (UPC)
[EN] Enzymes with a broad substrate specificity are of great interest both at the basic and applied level. Understanding the main parameters that make an enzyme substrate ambiguous could be thus important not only for their selection from the ever-in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a498b836a4163badb00c942e465279a
https://doi.org/10.1021/acscatal.0c05015
https://doi.org/10.1021/acscatal.0c05015
Publikováno v:
UPCommons. Portal del coneixement obert de la UPC
Universitat Politècnica de Catalunya (UPC)
Universitat Politècnica de Catalunya (UPC)
Biotechnological solutions will be a key aspect in our immediate future society, where optimized enzymatic processes through enzyme engineering might be an important solution for waste transformation, clean energy production, biodegradable materials,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f33f5f496d86fdd1b15c8625458be77
https://hdl.handle.net/2117/349184
https://hdl.handle.net/2117/349184
Publikováno v:
Advances in protein chemistry and structural biology. 122
With the increase of the need to use more sustainable processes for the industry in our society, the modeling of enzymes has become crucial to fully comprehend their mechanism of action and use this knowledge to enhance and design their properties. A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c532193a17a30d780a40719490afd77e
https://pubmed.ncbi.nlm.nih.gov/32951809
https://pubmed.ncbi.nlm.nih.gov/32951809
Publikováno v:
Advances in Protein Chemistry and Structural Biology ISBN: 9780128177624
UPCommons. Portal del coneixement obert de la UPC
Universitat Politècnica de Catalunya (UPC)
UPCommons. Portal del coneixement obert de la UPC
Universitat Politècnica de Catalunya (UPC)
With the increase of the need to use more sustainable processes for the industry in our society, the modeling of enzymes has become crucial to fully comprehend their mechanism of action and use this knowledge to enhance and design their properties. A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34900022981f2d7c994ba439ce376812
https://doi.org/10.1016/bs.apcsb.2020.06.001
https://doi.org/10.1016/bs.apcsb.2020.06.001
Publikováno v:
UPCommons. Portal del coneixement obert de la UPC
Universitat Politècnica de Catalunya (UPC)
Universitat Politècnica de Catalunya (UPC)
Water is frequently found inside proteins, carrying out important roles in catalytic reactions or molecular recognition tasks. Therefore, computational models that aim to study protein–ligand interactions usually have to include water effects throu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bce731eada40d05d2adf51cae9a3de70
Autor:
Sergi Roda, Henrik Terholsen, Jule Ruth Heike Meyer, Albert Cañellas-Solé, Victor Guallar, Uwe Bornscheuer, Masoud Kazemi
Publikováno v:
The Journal of Physical Chemistry B. 127(12):2661-2670
With advances in protein structure predictions, the number of available high-quality structures has increased dramatically. In light of these advances, structure-based enzyme engineering is expected to become increasingly important for optimizing bio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4f3a83e0c040aa741d5746cfb03e4b2