Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Sergi Monforte"'
Autor:
Núria Adelantado, Pablo Tarazona, Karlheinz Grillitsch, Xavier García-Ortega, Sergi Monforte, Francisco Valero, Ivo Feussner, Günther Daum, Pau Ferrer
Publikováno v:
Microbial Cell Factories, Vol 16, Iss 1, Pp 1-15 (2017)
Abstract Background Cultivation of recombinant Pichia pastoris (Komagataella sp.) under hypoxic conditions has a strong positive effect on specific productivity when the glycolytic GAP promoter is used for recombinant protein expression, mainly due t
Externí odkaz:
https://doaj.org/article/e02af9eb910a4d0c8a0e782bcecc127a
Publikováno v:
Biotechnology and Bioengineering. 116:1710-1720
The methanol-regulated alcohol oxidase promoter (P AOX1 ) of Pichia pastoris (syn. Komagataella spp.) is one of the strongest promoters for heterologous gene expression. Although increasing the gene dosage is a common strategy to improve recombinant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::061365c72d9fb73b2bf4650353a2ffe7
https://doi.org/10.1002/bit.26947
https://doi.org/10.1002/bit.26947
Autor:
Francisco Maresca, Màrius Tomàs-Gamisans, Joan Albiol, Cristiane Conte Paim de Andrade, Pau Ferrer, Sergi Monforte
Publikováno v:
Applied and Environmental Microbiology. 86
High-level expression and secretion of heterologous proteins in yeast causes an increased energy demand, which may result in altered metabolic flux distributions. Moreover, recombinant protein overproduction often results in ER-stress and oxidative s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f46109331067d1d1ac0c29e646e4162
https://doi.org/10.1128/aem.02038-19
https://doi.org/10.1128/aem.02038-19
Autor:
Màrius, Tomàs-Gamisans, Cristiane Conte Paim, Andrade, Francisco, Maresca, Sergi, Monforte, Pau, Ferrer, Joan, Albiol
Publikováno v:
Appl Environ Microbiol
High-level expression and secretion of heterologous proteins in yeast cause an increased energy demand, which may result in altered metabolic flux distributions. Moreover, recombinant protein overproduction often results in endoplasmic reticulum (ER)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7cd082ea307f34eebf7bba1bf258bed4
https://pubmed.ncbi.nlm.nih.gov/31757828
https://pubmed.ncbi.nlm.nih.gov/31757828
Publikováno v:
Biotechnology and bioengineering. 116(7)
The methanol-regulated alcohol oxidase promoter (P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::47c7a3e2b90913e27c99bd4afaaf8809
https://pubmed.ncbi.nlm.nih.gov/30712270
https://pubmed.ncbi.nlm.nih.gov/30712270