Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Sergi Cuartero"'
Autor:
Marie Christou-Kent, Sergi Cuartero, Carla Garcia-Cabau, Julia Ruehle, Julian Naderi, Julia Erber, Maria Victoria Neguembor, Marcos Plana-Carmona, Marc Alcoverro-Bertran, Luisa De Andres-Aguayo, Antonios Klonizakis, Eric Julià-Vilella, Cian Lynch, Manuel Serrano, Denes Hnisz, Xavier Salvatella, Thomas Graf, Grégoire Stik
Publikováno v:
Cell Reports, Vol 42, Iss 8, Pp 112897- (2023)
Summary: Cell identity is orchestrated through an interplay between transcription factor (TF) action and genome architecture. The mechanisms used by TFs to shape three-dimensional (3D) genome organization remain incompletely understood. Here we prese
Externí odkaz:
https://doaj.org/article/f919872c3ea44338bf8df8ef1c78878a
Autor:
André Baruchel, Jean-Pierre Bourquin, John Crispino, Sergi Cuartero, Henrik Hasle, Johann Hitzler, Jan-Henning Klusmann, Shai Izraeli, Andrew A. Lane, Sébastien Malinge, Karen R. Rabin, Irene Roberts, Sandra Ryeom, Sarah K. Tasian, Elvin Wagenblast
Publikováno v:
Haematologica, Vol 108, Iss 10 (2023)
Children with Down syndrome (DS, trisomy 21) are at a significantly higher risk of developing acute leukemia compared to the overall population. Many studies investigating the link between trisomy 21 and leukemia initiation and progression have been
Externí odkaz:
https://doaj.org/article/dcd8614ac85d403187af8360be79dab7
Autor:
Irene Robles-Rebollo, Sergi Cuartero, Adria Canellas-Socias, Sarah Wells, Mohammad M. Karimi, Elisabetta Mereu, Alexandra G. Chivu, Holger Heyn, Chad Whilding, Dirk Dormann, Samuel Marguerat, Inmaculada Rioja, Rab K. Prinjha, Michael P. H. Stumpf, Amanda G. Fisher, Matthias Merkenschlager
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Here the authors show inducible genes and enhancers are regulated mainly by transcriptional burst frequency and that this is coordinated in single cells and individual alleles. Cohesin, which is important for inducible gene expression, is largely dis
Externí odkaz:
https://doaj.org/article/fc245dbd45344cc8acb6dc172ee905b9
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
Classical driver mutations in acute myeloid leukemia (AML) typically affect regulators of cell proliferation, differentiation, and survival. The selective advantage of increased proliferation, improved survival, and reduced differentiation on leukemi
Externí odkaz:
https://doaj.org/article/c03f2961745a4c0f9f9e33daef0f41d1
Publikováno v:
Cancers, Vol 13, Iss 16, p 4144 (2021)
Children with Down syndrome (DS) are particularly prone to haematopoietic disorders. Paediatric myeloid malignancies in DS occur at an unusually high frequency and generally follow a well-defined stepwise clinical evolution. First, the acquisition of
Externí odkaz:
https://doaj.org/article/c27e5f73e6f146d7aeeb1ce78ab9912e
Publikováno v:
Biology Open, Vol 4, Iss 7, Pp 852-857 (2015)
The steroid hormone ecdysone is a central regulator of insect development. In this report we show that CTCF expression in the prothoracic gland is required for full transcriptional activation of the Halloween genes spookier, shadow and noppera-bo, wh
Externí odkaz:
https://doaj.org/article/cfcc7c85155a42288e63454357105107
Publikováno v:
Nature reviews. Immunology.
Immune cell development and activation demand the precise and coordinated control of transcriptional programmes. Three-dimensional (3D) organization of the genome has emerged as an important regulator of chromatin state, transcriptional activity and
Autor:
Marie Christou-Kent, Sergi Cuartero, Julia Ruehle, Carla Garcia-Cabau, Julian Naderi, Marcos Plana-Carmona, Marc Alcoverro-Bertran, Luisa De Andres-Aguayo, Eric Julia, Xavier Salvatella, Denes Hnisz, Thomas Graf, Gregoire Stik
Publikováno v:
SSRN Electronic Journal.
Publikováno v:
Frontiers in Oncology
Recercat. Dipósit de la Recerca de Catalunya
instname
Frontiers in Oncology, Vol 9 (2019)
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Recercat: Dipósit de la Recerca de Catalunya
Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Recercat. Dipósit de la Recerca de Catalunya
instname
Frontiers in Oncology, Vol 9 (2019)
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Recercat: Dipósit de la Recerca de Catalunya
Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Classical driver mutations in acute myeloid leukemia (AML) typically affect regulators of cell proliferation, differentiation, and survival. The selective advantage of increased proliferation, improved survival, and reduced differentiation on leukemi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf24c469f376319c2750503f83d282d5
https://hdl.handle.net/2072/445214
https://hdl.handle.net/2072/445214
Autor:
Enrique Vidal, Marc A. Marti-Renom, Tian V. Tian, Sergi Cuartero, Maria Vila-Casadesús, Amaya Abad, Jinmi Choi, François Le Dily, Patrick Cramer, Mercedes Barrero, Julen Mendieta-Esteban, Ralph Stadhouders, Gregoire Stik, Clara Berenguer, Thomas Graf, Beatrice Borsari
Publikováno v:
Nature Genetics
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
instname
Nature Genetics, 52(7), 655-661. Nature Publishing Group
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
instname
Nature Genetics, 52(7), 655-661. Nature Publishing Group
Three-dimensional organization of the genome is important for transcriptional regulation1-7. In mammals, CTCF and the cohesin complex create submegabase structures with elevated internal chromatin contact frequencies, called topologically associating
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fb0042d040c151698f2443eb2931801
https://fundanet.igtp.cat/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=4696
https://fundanet.igtp.cat/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=4696