New liver cancer genes identified by lentiviral vector-based insertional mutagenesis in mice are associated to differential survival in hepatocellular carcinoma patients

Autor: Ranzani M, Cesana D, Bartholomae CC, Sanvito F, Pala M, Benedicenti F, Gallina P, Sergi LS, Merella S, Bulfone A, Doglioni C, von Kalle C, Kim YJ, Schmidt M, Tonon G, Naldini L, Montini E

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_____10495::2bd5dea135c7a0a47bdc7655d04a5a3c

In vivo models to assess the risk of insertional mutagenesis in the liver upon vector systemic delivery

Autor: Ranzani M, Cesana D, Schmidt M, Sanvito F, Benedicenti F, Bartholoma C, Ponzoni M, Cantore A, Sergi LS, Doglioni C, VonKalle C, Naldini L, Montini E

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_____10495::39a761aa103b2818ccc1933574b09e2b

Mouse Models To Assess the Risk of Vector Insertional Mutagenesis upon Systemic Delivery

Autor: Ranzani M, Cesana D, Schmidt M, Sanvito F, Benedicenti F, Bartholoma C, Ponzoni M, Cantore A, Sergi LS, Doglioni C, VonKalle C, Naldini L, Montini E

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_____10495::69d8fd1d7e8ffa38b6b118109b235156

Modeling the genotoxicity of viral vector integration in a tumor prone hematopoietic stem cell transplantation model

Autor: Montini E, Cesana D, Schmidt M, Sanvito F, Ponzoni M, Sergi LS, Benedicenti F, Bartholomae C, di Serio C, Doglioni C, von Kalle C, Naldini L

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_____10495::c63877067fe45b7b5685a4de21c04aa6

Lentiviral correction of enzymatic activity restrains macrophage inflammation in adenosine deaminase 2 deficiency.

Autor: Zoccolillo M; San Raffaele Telethon Institute for Gene Therapy, IRCCS San Raffaele Scientific Institute, Milan, Italy.; Department of Medicine and Surgery, Tor Vergata University, Rome, Italy., Brigida I; San Raffaele Telethon Institute for Gene Therapy, IRCCS San Raffaele Scientific Institute, Milan, Italy., Barzaghi F; Pediatric Immunohematology and Bone Marrow Transplantation Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy., Scala S; San Raffaele Telethon Institute for Gene Therapy, IRCCS San Raffaele Scientific Institute, Milan, Italy., Hernández RJ; San Raffaele Telethon Institute for Gene Therapy, IRCCS San Raffaele Scientific Institute, Milan, Italy., Basso-Ricci L; San Raffaele Telethon Institute for Gene Therapy, IRCCS San Raffaele Scientific Institute, Milan, Italy., Colantuoni M; San Raffaele Telethon Institute for Gene Therapy, IRCCS San Raffaele Scientific Institute, Milan, Italy.; Vita-Salute San Raffaele University, Milan, Italy., Pettinato E; San Raffaele Telethon Institute for Gene Therapy, IRCCS San Raffaele Scientific Institute, Milan, Italy., Sergi LS; San Raffaele Telethon Institute for Gene Therapy, IRCCS San Raffaele Scientific Institute, Milan, Italy., Milardi G; San Raffaele Telethon Institute for Gene Therapy, IRCCS San Raffaele Scientific Institute, Milan, Italy., Capasso P; San Raffaele Telethon Institute for Gene Therapy, IRCCS San Raffaele Scientific Institute, Milan, Italy., Lombardo A; San Raffaele Telethon Institute for Gene Therapy, IRCCS San Raffaele Scientific Institute, Milan, Italy.; Vita-Salute San Raffaele University, Milan, Italy., Gregori S; San Raffaele Telethon Institute for Gene Therapy, IRCCS San Raffaele Scientific Institute, Milan, Italy., Sanvito F; GLP Test Facility, San Raffaele Telethon Institute for Gene Therapy, and.; Pathology Unit, Department of Experimental Oncology, IRCCS San Raffaele Scientific Institute, Milan, Italy., Schena F; Centro Malattie Autoinfiammatorie e Immunodeficienze, IRCCS Istituto Giannina Gaslini, Genoa, Italy., Cesaro S; Pediatric Hematology-Oncology, Ospedale della Donna e del Bambino, Verona, Italy., Conti F; Pediatric Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy., Pession A; Pediatric Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy., Benedetti F; CTMO Ematologia Azienda Ospedaliera Universitaria Integrate, Verona, Italy; and., Gattorno M; Centro Malattie Autoinfiammatorie e Immunodeficienze, IRCCS Istituto Giannina Gaslini, Genoa, Italy., Lee PY; Boston Children's Hospital, Boston, MA., Naldini L; San Raffaele Telethon Institute for Gene Therapy, IRCCS San Raffaele Scientific Institute, Milan, Italy.; Vita-Salute San Raffaele University, Milan, Italy., Cicalese MP; San Raffaele Telethon Institute for Gene Therapy, IRCCS San Raffaele Scientific Institute, Milan, Italy.; Pediatric Immunohematology and Bone Marrow Transplantation Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy., Aiuti A; San Raffaele Telethon Institute for Gene Therapy, IRCCS San Raffaele Scientific Institute, Milan, Italy.; Pediatric Immunohematology and Bone Marrow Transplantation Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy.; Vita-Salute San Raffaele University, Milan, Italy., Mortellaro A; San Raffaele Telethon Institute for Gene Therapy, IRCCS San Raffaele Scientific Institute, Milan, Italy.

Publikováno v: Blood advances [Blood Adv] 2021 Aug 24; Vol. 5 (16), pp. 3174-3187.