Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Sergey Zozulya"'
Autor:
Oleksandr Vovna, Hanna Kaydash, Leszek Rutkowski, Іvan Sakhno, Іvan Laktionov, Maryna Kabanets, Sergey Zozulya
Publikováno v:
Journal of Control Science and Engineering, Vol 2024 (2024)
In longwall coal mining, high methane concentrations pose a challenge. Cyber-physical air and gas protection systems ensure operational safety. However, safeguarding methane sensors from unauthorized interference is a key issue. This research aims to
Externí odkaz:
https://doaj.org/article/769c87922f254f5a86bb45e65743a099
Autor:
Alexey Lukin, Anna Bakholdina, Mikhail Chudinov, Oleksandra Onopchenko, Elena Zhuravel, Sergey Zozulya, Maxim Gureev, Mikhail Krasavin
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 36, Iss 1, Pp 1650-1657 (2021)
A set of 1,3,4-thiadiazole-2-carboxamides bearing a substituted biphenyl in the amide portion was synthesised and tested for agonistic activity towards free fatty acid receptor 1 (FFA1). The observed activity trends were impossible to rationalised ba
Externí odkaz:
https://doaj.org/article/9d3f63a014b74b7099392ec6f9080af1
Autor:
Mikhail Krasavin, Stanislav Kalinin, Sergey Zozulya, Anastasia Griniukova, Petro Borysko, Andrea Angeli, Claudiu T. Supuran
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 35, Iss 1, Pp 165-171 (2020)
Testing of an expanded, 800-compound set of analogues of the earlier described Strecker-type α-aminonitriles (selected from publicly available Enamine Ltd. Screening Collection) in thermal shift assay against bovine carbonic anhydrase (bCA) led to f
Externí odkaz:
https://doaj.org/article/e3b860d34fb7405fbc2cfb24b09d2294
Autor:
Mikhail Krasavin, Stanislav Kalinin, Sergey Zozulya, Anastasiia Gryniukova, Petro Borysko, Andrea Angeli, Claudiu T. Supuran
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 35, Iss 1, Pp 306-310 (2020)
The differential scanning fluorimetry (DSF) screening of 5.692 fragments in combination with benzenesulfonamide (BSA) against bovine carbonic anhydrase (bCA) delivered >100 hits that either caused, on their own, a significant thermal shift (ΔTm, °C
Externí odkaz:
https://doaj.org/article/fc10cfcdab0649f8818c3aee44de95e6
Autor:
Mikhail Krasavin, Alexey Lukin, Daria Bagnyukova, Nikolay Zhurilo, Ihor Zahanich, Sergey Zozulya
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 32, Iss 1, Pp 29-36 (2017)
A series of nine compounds based on 3-[4-(benzyloxy)phenyl]propanoic acid core containing a 1-oxa-9-azaspiro[5.5]undecane periphery was designed, synthesized and evaluated as free fatty acid 1 (FFA1 or GPR40) agonists. The spirocyclic appendages incl
Externí odkaz:
https://doaj.org/article/5d8999bb7c674341b63a5e6d5a3ae0a5
Autor:
Volker Adams, Victoria Gußen, Sergey Zozulya, André Cruz, Anselmo Moriscot, Axel Linke, Siegfried Labeit
Publikováno v:
Cells, Vol 9, Iss 10, p 2272 (2020)
Patients with malignant tumors frequently suffer during disease progression from a syndrome referred to as cancer cachexia (CaCax): CaCax includes skeletal muscle atrophy and weakness, loss of bodyweight, and fat tissues. Currently, there are no FDA
Externí odkaz:
https://doaj.org/article/e27e35e783a74fd58acdff998b21d80b
Publikováno v:
ASPET 2023 Annual Meeting Abstract - Drug Discovery and Development.
Autor:
Suzanne Trudel, Ivan George Fantus, James T. Dalton, Christopher C. Coss, Sergey Zozulya, Ellen Wei, Chungyee Leung-Hagesteijn, Jessica Zive, Zhihua Li, Young Trieu, Xiu-Zhi Yang, Sheng-Ben Liang
Purpose: Therapeutic strategies that target insulin-like growth factor 1 receptor (IGF-1R) hold promise in a wide variety of cancers including multiple myeloma (MM). In this study, we describe GTx-134, a novel small-molecule inhibitor of IGF-1R and i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12fc5cfc3fc3623263fe33b54b8d07ca
https://doi.org/10.1158/1078-0432.c.6519120.v1
https://doi.org/10.1158/1078-0432.c.6519120.v1
Autor:
Suzanne Trudel, Ivan George Fantus, James T. Dalton, Christopher C. Coss, Sergey Zozulya, Ellen Wei, Chungyee Leung-Hagesteijn, Jessica Zive, Zhihua Li, Young Trieu, Xiu-Zhi Yang, Sheng-Ben Liang
Supplementary Tables 1-3, Figures 1-3 from Molecular Target Characterization and Antimyeloma Activity of the Novel, Insulin-like Growth Factor 1 Receptor Inhibitor, GTx-134
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c25d21dc7271f0b7bcd48c29c07a45a
https://doi.org/10.1158/1078-0432.22442382
https://doi.org/10.1158/1078-0432.22442382
Autor:
Suzanne Trudel, Ivan George Fantus, James T. Dalton, Christopher C. Coss, Sergey Zozulya, Ellen Wei, Chungyee Leung-Hagesteijn, Jessica Zive, Zhihua Li, Young Trieu, Xiu-Zhi Yang, Sheng-Ben Liang
Supplementary Methods, Figure Legends 1-3 from Molecular Target Characterization and Antimyeloma Activity of the Novel, Insulin-like Growth Factor 1 Receptor Inhibitor, GTx-134
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11e86403c556648e9db826a17cfdd1e8
https://doi.org/10.1158/1078-0432.22442385.v1
https://doi.org/10.1158/1078-0432.22442385.v1