Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Sergey Vshyvenko"'
Autor:
Daniel Tarade, Megan Noel, Dennis Ma, Tyler Gilbert, Manika Gupta, Christopher Pignanelli, Siyaram Pandey, Sabrina Ma, Sergey Vshyvenko, Colin Curran, Jesse Ropat, Tomas Hudlicky, Fadi Mansour
Publikováno v:
The FASEB Journal. 32:417-430
Harsh adverse effects as a result of nonspecific targeting of chemotherapeutics currently pose obstacles in cancer therapy; thus, it would be invaluable to devise novel approaches to specifically target cancer cells. The natural compound pancratistat
Autor:
Sergey Vshyvenko, Alexander Dowhayko, Tyler Gilbert, James McNulty, Daniel Tarade, Christopher Pignanelli, Siyaram Pandey, Dennis Ma, Megan Noel, Kyle Stokes, Fadi Mansour, Tomas Hudlicky, Jonathan Collins, Scott Adams
Publikováno v:
Scientific Reports. 8
Scientific Reports 7; Article number: 42957; published online: 21 February 2017; updated: 04 July 2018 Jonathan Collins was omitted from the author list in the original version of this Article. This has been corrected in the PDF and HTML versions of
Autor:
Zemane W'Giorgis, Bradley John Hedberg, Audrey Weber, Sergey Vshyvenko, Tomas Hudlicky, Natalia Neverova
Publikováno v:
Advanced Synthesis & Catalysis. 357:83-87
The first active aza analogue of narciclasine was synthesized from a pentasubstituted derivative of nicotinic acid. The key features of the synthesis include a halogen dance of bromopyridine and an intramolecular Heck reaction with a conduramine deri
Autor:
Dennis Ma, Christopher Pignanelli, Daniel Tarade, Tyler Gilbert, Megan Noel, Fadi Mansour, Scott Adams, Alexander Dowhayko, Kyle Stokes, Sergey Vshyvenko, Jonathan Collins, Tomas Hudlicky, James McNulty, Siyaram Pandey
Publikováno v:
Scientific Reports
Enhanced mitochondrial stability and decreased dependence on oxidative phosphorylation confer an acquired resistance to apoptosis in cancer cells, but may present opportunities for therapeutic intervention. The compound pancratistatin (PST) has been
Autor:
Siyaram Pandey, Ian Tuffley, Sergey Vshyvenko, Tomas Hudlicky, Jon Scattolon, Anntherese E. Romero, Dennis Ma, Alexander Kornienko
Publikováno v:
Canadian Journal of Chemistry. 90:932-943
Several C-1 homologues of pancratistatin and 7-deoxypancratistatin were synthesized by a phenanthrene-phenathridone oxidative recyclization strategy. The key steps involved the enzymatic dihydroxylation of bromobenzene, addition of an aryl alane to a
Benzoxaboroles are a class of five-membered hemiboronic acids that recently attracted significant attention as a new pharmacophore on account of their unique structural and physicochemical properties and their ability to interact selectively with bio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04d16e9ad1e106102a3f3e2a4741d919
https://europepmc.org/articles/PMC5151146/
https://europepmc.org/articles/PMC5151146/
Autor:
Bradley John Hedberg, Sergey Vshyvenko, Audrey Weber, Natalia Neverova, Tomas Hudlicky, Zemane W'Giorgis
Publikováno v:
ChemInform. 46
Title compound (VI) is synthesized starting from pyridine derivative (I) over 12 steps in an overall yield of 2.05%.
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 21:4750-4752
The synthesis of two C-1 analogues of pancratistatin has been accomplished in 17 steps from bromobenzene. The key steps involved the enzymatic dihydroxylation, regioselective opening of epoxyaziridine 9 with the alane derived from 8, a solid-state si
Several unnatural derivatives of narciclasine were prepared in which the C-7 carbon was replaced with nitrogen. The 7-aza derivative and its N-oxide were prepared by the coupling of iodopicolinic acid with a conduramine unit derived chemoenzymaticall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f239cc8c4c7ad256de92c6b266662ea0
https://europepmc.org/articles/PMC4146675/
https://europepmc.org/articles/PMC4146675/