Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Sergey V. Sapozhnikov"'
Autor:
Nikita V. Shtyrlin, Mikhail V. Pugachev, Sergey V. Sapozhnikov, Marsel R. Garipov, Rusalia M. Vafina, Denis Y. Grishaev, Roman S. Pavelyev, Renata R. Kazakova, Mariya N. Agafonova, Alfiya G. Iksanova, Svetlana A. Lisovskaya, Marina I. Zeldi, Elena S. Krylova, Elena V. Nikitina, Alina E. Sabirova, Airat R. Kayumov, Yurii G. Shtyrlin
Publikováno v:
Molecules, Vol 25, Iss 18, p 4341 (2020)
A series of 108 novel quaternary bis-ammonium pyridoxine derivatives carrying various substituents at the quaternary nitrogen’s and acetal carbon was synthesized. Thirteen compounds exhibited antibacterial and antifungal activity (minimum inhibitor
Externí odkaz:
https://doaj.org/article/3173c442871045d0a08a8fd0266eb676
Autor:
Еlena S. Krylova, Denis Yu. Grishaev, Konstantin V. Balakin, Alfiya G. Iksanova, Yurii G. Shtyrlin, Nikita V. Shtyrlin, Еlena V. Nikitina, Alina E. Zamaldinova, Airat R. Kayumov, Sergey V. Sapozhnikov
Publikováno v:
Medicinal Chemistry Research. 26:3188-3202
A diverse library of 34 new quaternary mono-ammonium and bis-ammonium pyridoxine derivatives was synthesized, and their antibacterial activity against several clinically relevant bacterial strains was evaluated in vitro. Several mono-ammonium compoun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e2745319d2618c1877611fca43f5294
https://doi.org/10.1007/s00044-017-2012-9
https://doi.org/10.1007/s00044-017-2012-9
Autor:
Sergey V. Sapozhnikov, Anastasia Y. Druk, Denis Yu. Grishaev, Airat R. Kayumov, Mariya N. Agafonova, Yurii G. Shtyrlin, Milana N. Chirkova, Tatyana V. Nikishova, Renata R. Kazakova, Nikita V. Shtyrlin, Alina E. Sabirova, Elena V. Nikitina, Elena S. Krylova
Publikováno v:
European Journal of Medicinal Chemistry. 211:113100
A diverse series of 43 novel “soft antimicrobials” based on quaternary ammonium pyridoxine derivatives which include six-membered acetals and ketals of pyridoxine bound via cleavable linker moieties (amide, ester) with a fragment of fatty carboxy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ca7b62524c29a5031bbb10d5d28e35e
https://doi.org/10.1016/j.ejmech.2020.113100
https://doi.org/10.1016/j.ejmech.2020.113100
Autor:
Airat R. Kayumov, Denis Yu. Grishaev, Mariya N. Agafonova, Sergey V. Sapozhnikov, Elena V. Nikitina, Alfiya G. Iksanova, Svetlana A. Lisovskaya, Alina E. Sabirova, Nikita V. Shtyrlin, Yurii G. Shtyrlin, Elena S. Krylova, Marsel R. Garipov, Renata R. Kazakova, Mikhail V. Pugachev, R. M. Vafina, Marina I. Zeldi, Roman S. Pavelyev
Publikováno v:
Molecules
Molecules, Vol 25, Iss 4341, p 4341 (2020)
Volume 25
Issue 18
Molecules, Vol 25, Iss 4341, p 4341 (2020)
Volume 25
Issue 18
A series of 108 novel quaternary bis-ammonium pyridoxine derivatives carrying various substituents at the quaternary nitrogen&rsquo
s and acetal carbon was synthesized. Thirteen compounds exhibited antibacterial and antifungal activity (minimum
s and acetal carbon was synthesized. Thirteen compounds exhibited antibacterial and antifungal activity (minimum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fbd91dc09ef951c8ab0aa448b9c0df9
https://doi.org/10.3390/molecules25184341
https://doi.org/10.3390/molecules25184341
Autor:
Airat R. Kayumov, Konstantin V. Balakin, Oksana V. Bondar, Yurii G. Shtyrlin, Elena P. Mirchink, Sergey V. Sapozhnikov, Nikita V. Shtyrlin, Alexander A. Firsov, Elena B. Isakova, Albina S. Galiullina
Publikováno v:
BioMed Research International
ResearcherID
BioMed Research International, Vol 2016 (2016)
ResearcherID
BioMed Research International, Vol 2016 (2016)
A series of novel quaternary ammonium 4-deoxypyridoxine derivatives was synthesized. Two compounds demonstrated excellent activity against a panel of Gram-positive methicillin-resistantS. aureusstrains with MICs in the range of 0.5–2 μg/mL, exceed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2395c046dedbacfdcfec2f66e337835a
http://europepmc.org/articles/PMC5069379
http://europepmc.org/articles/PMC5069379
Autor:
Mikhail V. Pugachev, Sergey V. Sapozhnikov, G. R. Gazizova, Yurii G. Shtyrlin, Aliya A. Nureeva, Mikhail I. Bogachev, Nikita V. Shtyrlin, Elena Y. Trizna, Airat R. Kayumov
Publikováno v:
BioMed Research International
BioMed Research International, Vol 2015 (2015)
BioMed Research International, Vol 2015 (2015)
Opportunistic bacteriaStaphylococcus aureusandStaphylococcus epidermidisoften form rigid biofilms on tissues and inorganic surfaces. In the biofilm bacterial cells are embedded in a self-produced polysaccharide matrix and thereby are inaccessible to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::387e11c63ac82ec6944436674839bc1c
http://europepmc.org/articles/PMC4709599
http://europepmc.org/articles/PMC4709599
Autor:
Mikhail V. Pugachev, Airat R. Kayumov, Elena V. Nikitina, Yurii G. Shtyrlin, Marina I. Zeldi, Sergey V. Sapozhnikov, Mikhail I. Bogachev, Vladimir E. Evtygin, Svetlana V. Kuznetsova, Nikita V. Shtyrlin
Publikováno v:
World journal of microbiologybiotechnology. 32(1)
We studied the effects of quaternary bis-phosphonium and bis-ammonium salts of pyridoxine with lipophilic substituents on the survival and morphology of Staphylococcus aureus cells. We found that, while originating from the same base, they exhibit co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbe07c49b149d68ea219bf025bcc1a11
https://pubmed.ncbi.nlm.nih.gov/26712620
https://pubmed.ncbi.nlm.nih.gov/26712620
Autor:
Nikita V. Shtyrlin, Elena V. Nikitina, Rashid Z. Musin, Eugeny A. Berdnikov, Alfiya G. Iksanova, Sergey V. Sapozhnikov, Olga A. Lodochnikova, Yurii G. Shtyrlin, Mikhail V. Pugachev, L. P. Sysoeva
Publikováno v:
Bioorganicmedicinal chemistry. 21(23)
A series of 23 novel bis-phosphonium salts based on pyridoxine were synthesized and their antibacterial activities were evaluated in vitro. All compounds were inactive against gram-negative bacteria and exhibited the structure-dependent activity agai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::031bc7cea53badd826cf1f0cde98acd6
https://pubmed.ncbi.nlm.nih.gov/24139168
https://pubmed.ncbi.nlm.nih.gov/24139168