Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Sergey V. Melnikov"'
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
When ribosome-targeting antibiotics attack actively growing bacteria, they occupy ribosomal active centers, causing the ribosomes to stall or make errors that either halt cellular growth or cause bacterial death. However, emerging research indicates
Externí odkaz:
https://doaj.org/article/9d17ff3db04345299555bc9e1a2f43f1
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
Throughout the tree of life, cells and organisms enter states of dormancy or hibernation as a key feature of their biology: from a bacterium arresting its growth in response to starvation, to a plant seed anticipating placement in fertile ground, to
Externí odkaz:
https://doaj.org/article/6cee7a8bca414cfa85ad10a3b9a15d9c
Autor:
David Nicholson, Marco Salamina, Johan Panek, Karla Helena-Bueno, Charlotte R. Brown, Robert P. Hirt, Neil A. Ranson, Sergey V. Melnikov
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Many parasitic organisms contain molecular structures that are drastically smaller than analogous structures in non-parasitic organisms. Here the authors describe a cryo-EM structure of the ribosome from E. cuniculi that reveals that it compensated r
Externí odkaz:
https://doaj.org/article/0e64c80a3d2040fcab8346bf0aab04f2
Autor:
Karla Helena-Bueno, Chinenye L. Ekemezie, Charlotte R. Brown, Arnaud Baslé, James N. Blaza, Chris H. Hill, Sergey V. Melnikov
During starvation and stress, virtually all organisms arrest protein synthesis to conserve energy. Inactive ribosomes are converted into a dormant state, in which they are protected from damage by hibernation factor proteins. In bacteria, two major f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::76956aa9af2776805a7123a319d10d27
https://doi.org/10.1101/2022.11.24.517861
https://doi.org/10.1101/2022.11.24.517861
Autor:
Sergey V. Melnikov, Johan Panek, David Nicholson, Marco Salamina, Robert P. Hirt, Charlotte R. Brown, Karla Helena-Bueno, Neil A. Ranson
AO_SCPLOWBSTRACTC_SCPLOWThe evolution of microbial parasites involves the interplay of two opposing forces. On the one hand, the pressure to survive drives parasites to improve through Darwinian natural selection. On the other, frequent genetic drift
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce6933ecc2595af3f14b6b4c64413955
https://doi.org/10.1101/2021.09.06.458831
https://doi.org/10.1101/2021.09.06.458831
Autor:
Sergey V, Melnikov, Kasidet, Manakongtreecheep, Keith D, Rivera, Arthur, Makarenko, Darryl J, Pappin, Dieter, Söll
Publikováno v:
International Journal of Molecular Sciences
Microsporidia are fungi-like parasites that have the smallest known eukaryotic genome, and for that reason they are used as a model to study the phenomenon of genome decay in parasitic forms of life. Similar to other intracellular parasites that repr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::69fa643bea71a61e78c55c39a422cb39
https://pubmed.ncbi.nlm.nih.gov/30572624
https://pubmed.ncbi.nlm.nih.gov/30572624