Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Sergey V. Kutyakov"'
Autor:
Alexey A. Chistov, Stepan P. Chumakov, Igor E. Mikhnovets, Timofei D. Nikitin, Nikita A. Slesarchuk, Victoria I. Uvarova, Anna A. Rubekina, Yulia V. Nikolaeva, Eugene V. Radchenko, Evgeny V. Khvatov, Alexey A. Orlov, Vasilisa S. Frolenko, Maksim V. Sukhorukov, Ekaterina S. Kolpakova, Elena Y. Shustova, Anastasiya V. Galochkina, Philipp P. Streshnev, Eugene M. Osipov, Ksenia A. Sapozhnikova, Andrey V. Moiseenko, Vladimir A. Brylev, Gleb V. Proskurin, Yuri S. Dokukin, Sergey V. Kutyakov, Andrey V. Aralov, Vladimir A. Korshun, Sergei V. Strelkov, Vladimir A. Palyulin, Aydar A. Ishmukhametov, Evgeny A. Shirshin, Dmitry I. Osolodkin, Anna A. Shtro, Liubov I. Kozlovskaya, Vera A. Alferova, Alexey V. Ustinov
Publikováno v:
Antiviral Research. 209:105508
Amphipathic nucleoside and non-nucleoside derivatives of pentacyclic aromatic hydrocarbon perylene are known as potent non-cytotoxic broad-spectrum antivirals. Here we report 3-methyl-5-(perylen-3-ylethynyl)-uracil-1-acetic acid and its amides, a new
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb41103ed6709a5665d318635a1b4ac3
https://doi.org/10.1016/j.antiviral.2022.105508
https://doi.org/10.1016/j.antiviral.2022.105508
Autor:
I. V. Mikhura, Gunnar Westman, Vladimir A. Brylev, Brijesh Rathi, Alexey A. Chistov, Ilya O. Aparin, Liubov I. Kozlovskaya, Dmitry I. Osolodkin, Vladimir A. Palyulin, Philipp P. Streshnev, Vladimir A. Korshun, Nikita A. Slesarchuk, Alexey A. Orlov, Alexey V. Ustinov, Sergey V. Kutyakov, Nidhi Jain
Publikováno v:
European Journal of Medicinal Chemistry. 171:93-103
Rigid amphipathic fusion inhibitors (RAFIs) are potent antivirals based on a perylene core linked with a nucleoside moiety. Sugar-free analogues of RAFIs, 5-(perylen-3-ylethynyl)uracil-1-acetic acid 1 and its amides 2, were synthesized using combined
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e251c54f299cbdca8f711d7274b79a5
https://doi.org/10.1016/j.ejmech.2019.03.029
https://doi.org/10.1016/j.ejmech.2019.03.029
Autor:
Vladimir A. Korshun, Alexey A. Chistov, Arsentiy V. Guz, Alexey V. Ustinov, I. V. Mikhura, Sergey V. Kutyakov
Publikováno v:
Organic Preparations and Procedures International. 49:377-381
Rigid amphipathic fusion inhibitors (RAFIs), 5-arylethynyl-uracil nucleosides with bulky aryl groups, constitute a class of compounds active against enveloped viruses.1 Derivatives of perylene, a p...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a2d0b634e769f1f88e6873b866ea36d
https://doi.org/10.1080/00304948.2017.1343040
https://doi.org/10.1080/00304948.2017.1343040
Autor:
Alexey V. Ustinov, Alexey A. Chistov, Nikita M. Ivanov, I. V. Mikhura, Philipp P. Streshnev, Sergey V. Kutyakov, Vladimir A. Korshun, Anton V. Glybin
Publikováno v:
Tetrahedron Letters. 57:4821-4823
Two novel analogues of the highly fluorescent and potent antiviral compound, 5-(perylen-3-ylethynyl)-2′-deoxyuridine, containing elongated rigid linkers, butadiyne and 1,4-diethynylphenylene, were synthesized from the corresponding trimethylsilyl a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::353d19dbd966613007a3485cdbd02465
https://doi.org/10.1016/j.tetlet.2016.09.050
https://doi.org/10.1016/j.tetlet.2016.09.050
Autor:
Anton V. Glybin, Alexey V. Ustinov, Vladimir A. Korshun, Alexey A. Chistov, Sergey V. Kutyakov, Ilya O. Aparin, I. V. Mikhura
Publikováno v:
Tetrahedron Letters. 57:1003-1005
3-Ethynylperylene 1 , an important precursor for fluorescent dyes, fluorescent nucleosides, and potent nucleoside-based antivirals, has been prepared from perylene on a multigram scale (3 steps, 55% overall yield). A simple synthesis of 2-ethynylpery
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::942d03fe044e9455e8f7ab469066036e
https://doi.org/10.1016/j.tetlet.2016.01.067
https://doi.org/10.1016/j.tetlet.2016.01.067
Autor:
Andrey V. Aralov, Dmitry I. Osolodkin, Alexey A. Chistov, Gleb V. Proskurin, Sergey V. Kutyakov, Liubov I. Kozlovskaya, Vladimir A. Korshun, Alexey A. Orlov, Galina G. Karganova, Vladimir A. Palyulin
Publikováno v:
European journal of medicinal chemistry. 138
1-Substituted 4-perylen-2(3)-yl-1,2,3-triazoles, easily accessible by ‘click’ reaction and combining in one molecule a polyaromatic unit and a nitrogen heterocycle, were found to strongly inhibit the reproduction of enveloped viruses. 5-[4-(Peryl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17f0c600d6bef23a9a0914a7cc021c94
https://pubmed.ncbi.nlm.nih.gov/28675837
https://pubmed.ncbi.nlm.nih.gov/28675837
Autor:
Anton V. Glybin, I. V. Mikhura, Philip P. Streshnev, Arsentiy V. Guz, Alexey A. Chistov, Sergey V. Kutyakov, Margarita A. Mikhaleva, Vladimir A. Korshun, Alexey V. Ustinov
Publikováno v:
Collection Symposium Series.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea76c2598ed7b1f32dc42156c385dab8
https://doi.org/10.1135/css201414281
https://doi.org/10.1135/css201414281