Výsledky vyhledávání - "Sergey V. Abkin"

Exogenously delivered heat shock protein 70 displaces its endogenous analogue and sensitizes cancer cells to lymphocytes-mediated cytotoxicity

Autor: Maxim Shevtsov, Nikolai D. Aksenov, Natalia V. Bychkova, Darya A. Meshalkina, Elena Y. Komarova, Irina V. Guzhova, Sergey V. Abkin, Boris A. Margulis

Publikováno v: Oncotarget

// Maxim A. Shevtsov 1,* , Elena Y.Komarova 1,* , Darya A. Meshalkina 1,* , Natalia V. Bychkova 2 , Nikolai D. Aksenov 1 , Sergey V. Abkin 1 , Boris A. Margulis 1 , Irina V. Guzhova 1 1 Institute of Cytology of Russian Academy of Sciences, St. Peters

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b6117aa20f619b50e12f64f8e78cbda
http://europepmc.org/articles/PMC4102795

Zobrazit plný text záznamu

Intracellular and extracellular Hsp70 chaperone as a target for cancer therapy

Autor: Irina V. Guzhova, Maxim Shevtsov, Boris A. Margulis, Katerina M. Pankratova, Sergey V. Abkin

Publikováno v: International Journal of Hyperthermia. 29:399-408

Purpose: Heat shock protein 70 (HSPA family) is a multi-functional protein which protects individual cells from proteotoxic shock and the whole organism from microbial, viral and oncogenic pathogens. These diverse functions may depend upon ‘chapero

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed043bfa68e855e64c5b02d442b5e3f2
https://doi.org/10.3109/02656736.2013.807439

Zobrazit plný text záznamu

Plný text ve formátu HTML

Phloretin increases the anti-tumor efficacy of intratumorally delivered heat-shock protein 70 kDa (HSP70) in a murine model of melanoma

Autor: Olga S. Ostroumova, Irina V. Guzhova, Elena Y. Komarova, Maxim Shevtsov, Sergey V. Abkin, Boris A. Margulis, Darya A. Meshalkina

Publikováno v: Cancer immunology, immunotherapy : CII. 65(1)

Recombinant HSP70 chaperone exerts a profound anticancer effect when administered intratumorally. This action is based on the ability of HSP70 to penetrate tumor cells and extract its endogenous homolog. To enhance the efficacy of HSP70 cycling, we e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1546917ca80f9e7c0a3498cc37682af
https://pubmed.ncbi.nlm.nih.gov/26646850

Zobrazit plný text záznamu

Hsp70 chaperone-based gel composition as a novel immunotherapeutic anti-tumor tool

Autor: Elena Y. Komarova, Katerina M. Pankratova, Sergey V. Abkin, Boris A. Margulis, Irina V. Guzhova

The recent advances in designing Hsp70-based anti-cancer vaccines and the ability of the chaperone to penetrate inside a living cell prompted us to develop a non-invasive method for the treatment of surface tumors. We designed hydrogel-containing gel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::022f91f3aff60cfa638545d2c659582f
https://europepmc.org/articles/PMC3631097/

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání