Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Sergey V Shulga-Morskoy"'
Autor:
Ethan Clark, Gwendolyn M Wilmes, Rachel S Quesenberry, Sergey V Shulga-Morskoy, Violetta Medik, Stuart W. Hicks, Megan E Lewis, Stephen R Lutz, Anthony B Cooper, Hugh H. Russell, Elizabeth E. Reczek, Paulina Kocjan, Jesse A Stevenson, Kimberly L Carey
Publikováno v:
mAbs
Antibody combination therapeutics (ACTs) are polyvalent biopharmaceuticals that are uniquely suited for the control of complex diseases, including antibiotic resistant infectious diseases, autoimmune disorders and cancers. However, ACTs also represen
Autor:
A. M. Alekseev, Alexandra M. Cherskaya, Valery M. Lipkin, S.E. Permyakov, Sergey V. Shulga-Morskoy, Eugene A. Permyakov, Vladimir N. Uversky, A. A. Zargarov, Ivan I. Senin, Dmitry V. Zinchenko, Pavel P. Philippov
Publikováno v:
Russian Journal of Bioorganic Chemistry. 26:152-156
The structural properties of myristoylated forms of recombinant recoverin of the wild type and of its mutants with damaged second and/or third Ca2+-binding sites were studied by fluorimetry and circular dichroism. The interaction of wild-type recover
Autor:
Sergei E. Permyakov, Pavel P. Philippov, Dmitry V. Zinchenko, Vladimir N. Uversky, Ivan I. Senin, Alexandra M. Cherskaya, Eugene A. Permyakov, A. M. Alekseev, Sergey V. Shulga-Morskoy, Aminullah A. Zargarov, Valery M. Lipkin
Publikováno v:
Protein engineering. 13(11)
A molecule of the photoreceptor Ca(2+)-binding protein recoverin contains four potential EF-hand Ca(2+)-binding sites, of which only two, the second and the third, are capable of binding calcium ions. We have studied the effects of substitutions in t
Autor:
Pavel P. Philippov, Valery M. Lipkin, Dmitry Suchkov, Dmitry V. Zinchenko, Muhammad Akhtar, A. M. Alekseev, Sergey V. Shulga-Morskoy, Svetlana A Vaganova, Aminullah A. Zargarov, Svetlana A Shulga-Morskaya, Ivan I. Senin
Publikováno v:
FEBS Letters. (1-2):116-118
Several EF-hand recoverin mutants were obtained and their abilities to bind to photoreceptor membranes and to inhibit rhodopsin kinase were determined. The mutants with the `spoiled' 2nd, 3rd or (2nd+3rd) EF-hand structures did not act upon the kinas
Autor:
E. Yu. Zernii, V. N. Uverskii, Pavel P. Philippov, Sergey V. Shulga-Morskoy, Dmitry V. Zinchenko, Valery M. Lipkin, S.E. Permyakov, Eugene A. Permyakov, A. A. Zargarov, A. M. Alekseev, Alexandra M. Cherskaya, Ivan I. Senin
Publikováno v:
Scopus-Elsevier
ResearcherID
ResearcherID
Unlike wild type recoverin with only two (the second and the third) functioning Ca+2-binding sites out of four potential ones, the +EF4 mutant contains a third active Ca+2-binding site. This site was reconstructed from the fourth potential Ca+2-bindi
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