Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Sergey V Kulemzin"'
Autor:
Sergey V Guselnikov, Tatyana N Belovezhets, Sergey V Kulemzin, Andrey A Gorchakov, Alexander V Taranin
Publikováno v:
BioTechniques, Vol 67, Iss 4, Pp 184-187 (2019)
Cloning VH and VL genes from individual antigen-specific B cells is an attractive approach for producing monoclonal antibodies of the desired specificity. Current RT-PCR protocols, however, result in the successful identification of VH and VL gene pa
Externí odkaz:
https://doaj.org/article/56d4dfdee4f743cb9a777b95dc095966
Autor:
Sergey V. Guselnikov, Konstantin O. Baranov, Sergey V. Kulemzin, Tatyana N. Belovezhets, Anton N. Chikaev, Svetlana V. Murasheva, Olga Y. Volkova, Ludmila V. Mechetina, Alexander M. Najakshin, Nikolai A. Chikaev, Pavel P. Solodkov, Maria V. Sergeeva, Alexander V. Smirnov, Irina A. Serova, Oleg L. Serov, Alexander G. Markhaev, Yulia V. Kononova, Alexander Y. Alekseev, Marina A. Gulyaeva, Daria M. Danilenko, Nariman R. Battulin, Alexander M. Shestopalov, Alexander V. Taranin
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
The COVID-19 pandemic has uncovered the high genetic variability of the SARS-CoV-2 virus and its ability to evade the immune responses that were induced by earlier viral variants. Only a few monoclonal antibodies that have been reported to date are c
Externí odkaz:
https://doaj.org/article/6da10109f6fb4cc2aa3729d2219d4170
Autor:
Evgeniy V. Zuev, Oksana Anatolievna Markova, Sergey V. Kulemzin, Dmitry A. Poteryaev, Natalya A. Litvinova, Ilya A. Korotkevich, Taisiya V. Grigiryeva, Ravil A. Khamitov
Publikováno v:
Инфекция и иммунитет, Vol 13, Iss 5, Pp 853-863 (2023)
Introduction. The SARS-CoV-2 coronavirus pandemic has been a major challenge for all areas of medical science, causing a surge of new developments in various fields ranging from diagnostic techniques to therapeutic and preventive approaches. Intranas
Externí odkaz:
https://doaj.org/article/bf26d6d9c231466fbb3e96dcac5045db
Autor:
Pavel P. Solodkov, Alexander M. Najakshin, Nikolai A. Chikaev, Sergey V. Kulemzin, Ludmila V. Mechetina, Konstantin O. Baranov, Sergey V. Guselnikov, Andrey A. Gorchakov, Tatyana N. Belovezhets, Anton N. Chikaev, Olga Y. Volkova, Alexander G. Markhaev, Yulia V. Kononova, Alexander Y. Alekseev, Marina A. Gulyaeva, Alexander M. Shestopalov, Alexander V. Taranin
Publikováno v:
Vaccines, Vol 12, Iss 2, p 129 (2024)
The emergence of SARS-CoV-2 mutant variants has posed a significant challenge to both the prevention and treatment of COVID-19 with anti-coronaviral neutralizing antibodies. The latest viral variants demonstrate pronounced resistance to the vast majo
Externí odkaz:
https://doaj.org/article/3f932639df4445969276ce69457f349c
Autor:
Sergey V. Kulemzin, Sergey V. Guselnikov, Boris G. Nekrasov, Svetlana V. Molodykh, Irina N. Kuvshinova, Svetlana V. Murasheva, Tatyana N. Belovezhets, Andrey A. Gorchakov, Anton N. Chikaev, Nikolai A. Chikaev, Olga Y. Volkova, Anna A. Yurina, Alexander M. Najakshin, Alexander V. Taranin
Publikováno v:
Vaccines, Vol 12, Iss 1, p 55 (2024)
SARS-CoV-2 has a relatively high mutation rate, with the frequent emergence of new variants of concern (VOCs). Each subsequent variant is more difficult to neutralize by the sera of vaccinated individuals and convalescents. Some decrease in neutraliz
Externí odkaz:
https://doaj.org/article/aad5822efb674e47a6cbbe12f6831599
Autor:
Ekaterina A. Astakhova, Maria G. Byazrova, Gaukhar M. Yusubalieva, Sergey V. Kulemzin, Natalia A. Kruglova, Alexey G. Prilipov, Vladimir P. Baklaushev, Andrey A. Gorchakov, Alexander V. Taranin, Alexander V. Filatov
Publikováno v:
Cells, Vol 11, Iss 13, p 1991 (2022)
Both SARS-CoV-2 infection and vaccination have previously been demonstrated to elicit robust, yet somewhat limited immunity against the evolving variants of SARS-CoV-2. Nevertheless, reports performing side-by-side comparison of immune responses foll
Externí odkaz:
https://doaj.org/article/21eee7f5cd5547fdb89d07dfe90d8652
Autor:
Sergey V. Guselnikov, Konstantin O. Baranov, Alexander M. Najakshin, Ludmila V. Mechetina, Nikolai A. Chikaev, Alexey I. Makunin, Sergey V. Kulemzin, Daria A. Andreyushkova, Matthias Stöck, Sven Wuertz, Jörn Gessner, Wesley C. Warren, Manfred Schartl, Vladimir A. Trifonov, Alexander V. Taranin
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
The aim of this study was to fill important gaps in the evolutionary history of immunoglobulins by examining the structure and diversity of IgL genes in non-teleost ray-finned fish. First, based on the bioinformatic analysis of recent transcriptomic
Externí odkaz:
https://doaj.org/article/b063c656b5334ce5a1c36d9dcba42986
Autor:
Sergey V. Kulemzin, Maria V. Sergeeva, Konstantin O. Baranov, Andrey A. Gorchakov, Sergey V. Guselnikov, Tatyana N. Belovezhets, Olga Yu. Volkova, Alexander M. Najakshin, Nikolai A. Chikaev, Daria M. Danilenko, Alexander V. Taranin
Publikováno v:
Journal of Personalized Medicine; Volume 12; Issue 6; Pages: 895
Immune evasion of SARS-CoV-2 undermines current strategies tocounteract the pandemic, with the efficacy of therapeutic virus-neutralizing monoclonal antibodies (nAbs) being affected the most. In this work, we asked whether two previously identified h
Publikováno v:
European Urology. 77:299-308
Context Progress achieved in the treatment of prostate cancer (PCa) with surgical, radiation, and hormonal therapies has drastically reduced mortality from this disease. Yet, patients with advanced PCa have few, if any, curative options. Recent succe
Autor:
Maria G. Byazrova, Sergey V. Kulemzin, Ekaterina A. Astakhova, Tatyana N. Belovezhets, Grigory A. Efimov, Anton N. Chikaev, Ilya O. Kolotygin, Andrey A. Gorchakov, Alexander V. Taranin, Alexander V. Filatov
Publikováno v:
Frontiers in Immunology. 13
The development of effective vaccines against SARS-CoV-2 remains a global health priority. Despite extensive use, the effects of Sputnik V on B cell immunity need to be explored in detail. We performed comprehensive profiling of humoral and B cell re