Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Sergey V Guselnikov"'
Autor:
Sergey V Guselnikov, Tatyana N Belovezhets, Sergey V Kulemzin, Andrey A Gorchakov, Alexander V Taranin
Publikováno v:
BioTechniques, Vol 67, Iss 4, Pp 184-187 (2019)
Cloning VH and VL genes from individual antigen-specific B cells is an attractive approach for producing monoclonal antibodies of the desired specificity. Current RT-PCR protocols, however, result in the successful identification of VH and VL gene pa
Externí odkaz:
https://doaj.org/article/56d4dfdee4f743cb9a777b95dc095966
Autor:
Sergey V. Guselnikov, Konstantin O. Baranov, Sergey V. Kulemzin, Tatyana N. Belovezhets, Anton N. Chikaev, Svetlana V. Murasheva, Olga Y. Volkova, Ludmila V. Mechetina, Alexander M. Najakshin, Nikolai A. Chikaev, Pavel P. Solodkov, Maria V. Sergeeva, Alexander V. Smirnov, Irina A. Serova, Oleg L. Serov, Alexander G. Markhaev, Yulia V. Kononova, Alexander Y. Alekseev, Marina A. Gulyaeva, Daria M. Danilenko, Nariman R. Battulin, Alexander M. Shestopalov, Alexander V. Taranin
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
The COVID-19 pandemic has uncovered the high genetic variability of the SARS-CoV-2 virus and its ability to evade the immune responses that were induced by earlier viral variants. Only a few monoclonal antibodies that have been reported to date are c
Externí odkaz:
https://doaj.org/article/6da10109f6fb4cc2aa3729d2219d4170
Autor:
Pavel P. Solodkov, Alexander M. Najakshin, Nikolai A. Chikaev, Sergey V. Kulemzin, Ludmila V. Mechetina, Konstantin O. Baranov, Sergey V. Guselnikov, Andrey A. Gorchakov, Tatyana N. Belovezhets, Anton N. Chikaev, Olga Y. Volkova, Alexander G. Markhaev, Yulia V. Kononova, Alexander Y. Alekseev, Marina A. Gulyaeva, Alexander M. Shestopalov, Alexander V. Taranin
Publikováno v:
Vaccines, Vol 12, Iss 2, p 129 (2024)
The emergence of SARS-CoV-2 mutant variants has posed a significant challenge to both the prevention and treatment of COVID-19 with anti-coronaviral neutralizing antibodies. The latest viral variants demonstrate pronounced resistance to the vast majo
Externí odkaz:
https://doaj.org/article/3f932639df4445969276ce69457f349c
Autor:
Sergey V. Kulemzin, Sergey V. Guselnikov, Boris G. Nekrasov, Svetlana V. Molodykh, Irina N. Kuvshinova, Svetlana V. Murasheva, Tatyana N. Belovezhets, Andrey A. Gorchakov, Anton N. Chikaev, Nikolai A. Chikaev, Olga Y. Volkova, Anna A. Yurina, Alexander M. Najakshin, Alexander V. Taranin
Publikováno v:
Vaccines, Vol 12, Iss 1, p 55 (2024)
SARS-CoV-2 has a relatively high mutation rate, with the frequent emergence of new variants of concern (VOCs). Each subsequent variant is more difficult to neutralize by the sera of vaccinated individuals and convalescents. Some decrease in neutraliz
Externí odkaz:
https://doaj.org/article/aad5822efb674e47a6cbbe12f6831599
Autor:
Sergey V. Guselnikov, Konstantin O. Baranov, Alexander M. Najakshin, Ludmila V. Mechetina, Nikolai A. Chikaev, Alexey I. Makunin, Sergey V. Kulemzin, Daria A. Andreyushkova, Matthias Stöck, Sven Wuertz, Jörn Gessner, Wesley C. Warren, Manfred Schartl, Vladimir A. Trifonov, Alexander V. Taranin
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
The aim of this study was to fill important gaps in the evolutionary history of immunoglobulins by examining the structure and diversity of IgL genes in non-teleost ray-finned fish. First, based on the bioinformatic analysis of recent transcriptomic
Externí odkaz:
https://doaj.org/article/b063c656b5334ce5a1c36d9dcba42986
Autor:
Sergey V. Kulemzin, Maria V. Sergeeva, Konstantin O. Baranov, Andrey A. Gorchakov, Sergey V. Guselnikov, Tatyana N. Belovezhets, Olga Yu. Volkova, Alexander M. Najakshin, Nikolai A. Chikaev, Daria M. Danilenko, Alexander V. Taranin
Publikováno v:
Journal of Personalized Medicine; Volume 12; Issue 6; Pages: 895
Immune evasion of SARS-CoV-2 undermines current strategies tocounteract the pandemic, with the efficacy of therapeutic virus-neutralizing monoclonal antibodies (nAbs) being affected the most. In this work, we asked whether two previously identified h
Autor:
Evdokiya S. Reshetnikova, Chikaev Na, Peter D. Burrows, Sergey V. Guselnikov, Olga Y. Volkova, Boris Y. Alabyev, Ludmila V. Mechetina, Alexander M. Najakshin, Dorottya Kövesdi, Gabriella Sármay, Alexander V. Taranin
Publikováno v:
Cellular Immunology. 272:182-192
FCRLA is an intracellular B cell protein that belongs to the FcR-like family. Using newly generated FCRLA-specific antibodies, we studied the constitutive expression pattern of mouse FCRLA and monitored changes during an immune response and following
Publikováno v:
Molecular Immunology. 46:1775-1786
In jawed vertebrates, the heterogeneous nonclassical MHC class Ib (class Ib) gene family encodes molecules structurally similar to classical MHC class Ia (class Ia) but with more limited tissue distribution and lower polymorphism. In mammals, class I
Autor:
Alexander M. Najakshin, O. V. Volkova, Nicolai A. Chikaev, Sergey V. Guselnikov, Sergey V. Kulemzin, Alexander V. Taranin, Evdokiya S. Reshetnikova, Ludmila V. Mechetina, Konstantin O Baranov
SLAMF9 is a member of the signaling lymphocyte-activating molecule (SLAM) immunoreceptor family. The SLAM family receptors are expressed in a broad range of immune cells and play an important role in immunity. To date, SLAMF9 is the least studied mem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6006e4b70aca4cd9b6d4442f751caa3f
https://europepmc.org/articles/PMC4151055/
https://europepmc.org/articles/PMC4151055/
Autor:
Petr P. Laktionov, Alexander M. Najakshin, Sergey V. Guselnikov, Alexander V. Taranin, Konstantin O Baranov
Publikováno v:
Immunogenetics. 63(10)
We studied the evolution of the CD2 family in tetrapods by extracting and analyzing CD2-like genes from the genome of the amphibian species Silurana (Xenopus) tropicalis. An exhaustive analysis of the genomic and cDNA databases resulted in the identi