Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Sergey V, Shorshnev"'
Autor:
Ivan O. Maslov, Tatiana V. Zinevich, Olga G. Kirichenko, Mikhail V. Trukhan, Sergey V. Shorshnev, Natalya O. Tuaeva, Maxim A. Gureev, Amelia D. Dahlén, Yuri B. Porozov, Helgi B. Schiöth, Vladimir M. Trukhan
Publikováno v:
Pharmaceuticals, Vol 15, Iss 3, p 273 (2022)
Compounds that contain (R)-3-amino-4-(2,4,5-trifluorophenyl)butanoic acid substituted with bicyclic amino moiety (2-aza-bicyclo[2.2.1]heptane) were designed using molecular modelling methods, synthesised, and found to be potent DPP-4 (dipeptidyl pept
Externí odkaz:
https://doaj.org/article/eb8f6f6ae0d9464ea7a070f9095c60ed
Autor:
Trukhan, Ivan O. Maslov, Tatiana V. Zinevich, Olga G. Kirichenko, Mikhail V. Trukhan, Sergey V. Shorshnev, Natalya O. Tuaeva, Maxim A. Gureev, Amelia D. Dahlén, Yuri B. Porozov, Helgi B. Schiöth, Vladimir M.
Publikováno v:
Pharmaceuticals; Volume 15; Issue 3; Pages: 273
Compounds that contain (R)-3-amino-4-(2,4,5-trifluorophenyl)butanoic acid substituted with bicyclic amino moiety (2-aza-bicyclo[2.2.1]heptane) were designed using molecular modelling methods, synthesised, and found to be potent DPP-4 (dipeptidyl pept
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::4ef4e55e56cb631a9081a25e09ab4bb6
Autor:
Ivan O, Maslov, Tatiana V, Zinevich, Olga G, Kirichenko, Mikhail V, Trukhan, Sergey V, Shorshnev, Natalya O, Tuaeva, Maxim A, Gureev, Amelia D, Dahlén, Yuri B, Porozov, Helgi B, Schiöth, Vladimir M, Trukhan
Publikováno v:
Pharmaceuticals (Basel, Switzerland). 15(3)
Compounds that contain (R)-3-amino-4-(2,4,5-trifluorophenyl)butanoic acid substituted with bicyclic amino moiety (2-aza-bicyclo[2.2.1]heptane) were designed using molecular modelling methods, synthesised, and found to be potent DPP-4 (dipeptidyl pept
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::215fc0965c6480cc169177fda35b4fe0
https://pubmed.ncbi.nlm.nih.gov/35337071
https://pubmed.ncbi.nlm.nih.gov/35337071
Publikováno v:
Tetrahedron Letters. 50:2899-2903
Reactions of quinazoline 1 with indole, pyrogallol and 1-phenyl-3-methylpyrazol-5-one in the presence of acid led to C-4 adducts 2, 3 and 5. Adduct 4 is formed by heating 1 with 1,3-dimethylbarbituric acid without acid catalysis. 1-Phenyl-3-methylpyr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c6811c335a132ba8931aa943ae8631b
https://doi.org/10.1016/j.tetlet.2009.03.199
https://doi.org/10.1016/j.tetlet.2009.03.199
Publikováno v:
Arkivoc. 2009:21-45
Sterically hindered 2,4-disubstituted 3-(1,2,4-oxadiazol-3-yl)-, 3-(imidazol-2-yl)- and 3-(thiazol-2yl)pyridines were synthesized from the corresponding nicotinonitriles via amidoximes, amidines and thioamides, respectively. N-Alkyl- and N-arylamidin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::855d0fe41fa72c61a54a3bee686e1b32
https://doi.org/10.3998/ark.5550190.0010.403
https://doi.org/10.3998/ark.5550190.0010.403
Publikováno v:
Tetrahedron. 63:12195-12201
Isoxazoles bearing alkyl or carbamoyl groups were transformed into the corresponding pyrazoles in high yields by the treatment with hydrazine in methanol in the presence of a hydrogenation catalyst, e.g., Raney nickel, at ambient temperature. For the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de31a248e7a4890f7d81f7da0706007e
https://doi.org/10.1016/j.tet.2007.09.046
https://doi.org/10.1016/j.tet.2007.09.046
Autor:
Andrei A. Vasil'ev, Sergey V. Shorshnev, Sergey I. Sviridov, Natalia L. Sergovskaya, Marina V. Chirskaya
Publikováno v:
Tetrahedron. 62:2639-2647
Arylboronic acids having a remote azido group were prepared from the corresponding azidosubstituted aryl bromides via lithiation and treatment with trialkyl borates. Preparative yields were achieved when the starting aryl bromides possessed ortho-alk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2cb9da35b1f5b43f25ae6f6f9003c71
https://doi.org/10.1016/j.tet.2005.12.026
https://doi.org/10.1016/j.tet.2005.12.026
Autor:
Andrei A. Vasil'ev, Sergey M. Lukyanov, Aleksandr E. Stepanov, Igor V. Bliznets, Grigory G. Aleksandrov, Sergey V. Shorshnev
Publikováno v:
Tetrahedron. 62:1849-1863
Sterically hindered 2,4-disubstituted 3-(5-tetrazolyl)pyridines were synthesized from corresponding nicotinonitriles using microwave technology. 2-Methylnicotinonitriles were converted into the 2-azidomethyl-3-cyanopyridines via 2-hydroxymethyl and 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf0e10e5bb214dbc5defe2a8798bd6be
https://doi.org/10.1016/j.tet.2005.11.039
https://doi.org/10.1016/j.tet.2005.11.039
Publikováno v:
Synthesis. 2006:156-160
A convenient approach to 4,5-disubstituted 3-hydroxymethyl-1.2.4-triazoles as well as to the corresponding 3-chloromethyl and 3-carboxaldehyde derivatives was developed starting from 3-mercapto-1,2,4-triazoles which can, in turn, be readily obtained
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::86f4dd2cc0768d7c89f732be62b8ba44
https://doi.org/10.1055/s-2005-921754
https://doi.org/10.1055/s-2005-921754
Autor:
Grigory G. Aleksandrov, Sergey V. Shorshnev, Sergey I. Sviridov, Aleksandr E. Stepanov, Tatyana V. Lukina
Publikováno v:
Tetrahedron Letters. 47:51-54
2,4,7-Trisubstituted hydrogenated pyrazino[1,2-a]pyrazines as potential β-turn mimetics were prepared for the first time in a stereoselective synthesis from hexahydro[1,2,3]triazolo[1,5-a]pyrazines.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::addfc8aa651e993c8dd93c02e25b79d1
https://doi.org/10.1016/j.tetlet.2005.10.130
https://doi.org/10.1016/j.tetlet.2005.10.130