Zobrazeno 1 - 10
of 474
pro vyhledávání: '"Sergey V, Razin"'
Autor:
Semen A. Doronin, Artem A. Ilyin, Anna D. Kononkova, Mikhail A. Solovyev, Oxana M. Olenkina, Valentina V. Nenasheva, Elena A. Mikhaleva, Sergey A. Lavrov, Anna Y. Ivannikova, Ruslan A. Simonov, Anna A. Fedotova, Ekaterina E. Khrameeva, Sergey V. Ulianov, Sergey V. Razin, Yuri Y. Shevelyov
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-18 (2024)
Abstract Transport of macromolecules through the nuclear envelope (NE) is mediated by nuclear pore complexes (NPCs) consisting of nucleoporins (Nups). Elys/Mel-28 is the Nup that binds and connects the decondensing chromatin with the reassembled NPCs
Externí odkaz:
https://doaj.org/article/634150327a894b9faa6375a04bf66413
Autor:
Alexey A. Gavrilov, Grigory S. Evko, Aleksandra A. Galitsyna, Sergey V. Ulianov, Tatiana V. Kochetkova, Alexander Y. Merkel, Alexander V. Tyakht, Sergey V. Razin
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-8 (2023)
Abstract Proximity ligation approaches, which are widely used to study the spatial organization of the genome, also make it possible to reveal patterns of RNA-DNA interactions. Here, we use RedC, an RNA-DNA proximity ligation approach, to assess the
Externí odkaz:
https://doaj.org/article/239e1657be44420789f5ac60e9294ed5
Publikováno v:
BMC Bioinformatics, Vol 23, Iss 1, Pp 1-8 (2022)
Abstract Background Understanding the role of various factors in 3D genome organization is essential to determine their impact on shaping large-scale chromatin units such as euchromatin (A) and heterochromatin (B) compartments. At this level, chromat
Externí odkaz:
https://doaj.org/article/a17a623703024e3ba1877b8501b1ca7c
Autor:
Ignat V. Sonets, Nikita V. Dovidchenko, Sergey V. Ulianov, Maria S. Yarina, Stanislav I. Koshechkin, Sergey V. Razin, Larissa M. Krasnopolskaya, Alexander V. Tyakht
Publikováno v:
Journal of Fungi, Vol 9, Iss 10, p 1020 (2023)
Ganoderma lucidum exhibits the ability to synthesize a diverse range of biologically active molecules with significant pharmaceutical potential, including xylomannan and fucogalactan, which have demonstrated antitumor activity. However, there exists
Externí odkaz:
https://doaj.org/article/dd4273eec19b4b2d8b05e8e421a6422e
Publikováno v:
Epigenetics & Chromatin, Vol 14, Iss 1, Pp 1-11 (2021)
Abstract Cohesin is a key organizer of chromatin folding in eukaryotic cells. The two main activities of this ring-shaped protein complex are the maintenance of sister chromatid cohesion and the establishment of long-range DNA–DNA interactions thro
Externí odkaz:
https://doaj.org/article/a6fa8998948642d7b75363cb20dd92f4
Autor:
Artem V. Luzhin, Arkadiy K. Golov, Alexey A. Gavrilov, Artem K. Velichko, Sergey V. Ulianov, Sergey V. Razin, Omar L. Kantidze
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Chromatin loops represent one of the major levels of hierarchical folding of the genome. Although the situation is evolving, current methods have various difficulties with the accurate mapping of loops even in mammalian Hi-C data, and most o
Externí odkaz:
https://doaj.org/article/69ccde0abe7745c6ae22aa14c46e9b5f
Autor:
Sergey V. Ulianov, Vlada V. Zakharova, Aleksandra A. Galitsyna, Pavel I. Kos, Kirill E. Polovnikov, Ilya M. Flyamer, Elena A. Mikhaleva, Ekaterina E. Khrameeva, Diego Germini, Mariya D. Logacheva, Alexey A. Gavrilov, Alexander S. Gorsky, Sergey K. Nechaev, Mikhail S. Gelfand, Yegor S. Vassetzky, Alexander V. Chertovich, Yuri Y. Shevelyov, Sergey V. Razin
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Genomes are partitioned into topologically associating domains (TADs). Here the authors present single-nucleus Hi-C maps in Drosophila at 10 kb resolution, demonstrating the presence of chromatin compartments in individual nuclei, and partitioning of
Externí odkaz:
https://doaj.org/article/8dcfb2d70fc24ab89ca4dad46c6324c9
Autor:
Valeriia Ivanova, Ekaterina Chernevskaya, Petr Vasiluev, Artem Ivanov, Ivan Tolstoganov, Daria Shafranskaya, Vladimir Ulyantsev, Anton Korobeynikov, Sergey V. Razin, Natalia Beloborodova, Sergey V. Ulianov, Alexander Tyakht
Publikováno v:
Frontiers in Microbiology, Vol 12 (2022)
Gut microbiome in critically ill patients shows profound dysbiosis. The most vulnerable is the subgroup of chronically critically ill (CCI) patients – those suffering from long-term dependence on support systems in intensive care units. It is impor
Externí odkaz:
https://doaj.org/article/6a982515a354401fb17ff78ab7006370
Autor:
Pavel I. Kos, Aleksandra A. Galitsyna, Sergey V. Ulianov, Mikhail S. Gelfand, Sergey V. Razin, Alexander V. Chertovich
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 11 (2021)
Construction of chromosomes 3D models based on single cell Hi-C data constitute an important challenge. We present a reconstruction approach, DPDchrom, that incorporates basic knowledge whether the reconstructed conformation should be coil-like or gl
Externí odkaz:
https://doaj.org/article/2ceee2102cc94e91b57e800ca7e37ac2
Autor:
Omar L. Kantidze, Artem V. Luzhin, Ekaterina V. Nizovtseva, Alfiya Safina, Maria E. Valieva, Arkadiy K. Golov, Artem K. Velichko, Alexander V. Lyubitelev, Alexey V. Feofanov, Katerina V. Gurova, Vasily M. Studitsky, Sergey V. Razin
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Curaxins are a recently discovered class of anti-cancer agents that disturbs DNA/histone interactions within. Here the authors provide evidence that curaxins affect the spatial genome organization and compromise enhancer-promoter communication necess
Externí odkaz:
https://doaj.org/article/6ad5ed2c5629478aaf374797be05a1e6