Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Sergey Sikora"'
Autor:
Nima Ghasemzadeh, Maria M. Brooks, Helen Vlachos, Regina Hardison, Sergey Sikora, Laurence Sperling, Arshed A. Quyyumi, Stephen E. Epstein
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 6, Iss 7 (2017)
BackgroundIn a previous study, we found that a biomarker risk score (BRS) comprised of C‐reactive protein, fibrin‐degradation products, and heat shock protein‐70 predicts risk of myocardial infarction and death in coronary artery disease patien
Externí odkaz:
https://doaj.org/article/c55141802b0b4904b71547946d07413b
Autor:
Dror Luger, Alex Kharazi, Juan C. Frias, David K. Glover, Grigory Vertelov, Sergey Sikora, M. Teresa Albelda, Michael J. Lipinski, Ron Waksman, Peter C. Westman, Stephen E. Epstein, Julien Dimastromatteo
Publikováno v:
CIRCULATION RESEARCH
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname
Rationale: Virtually all mesenchymal stem cell (MSC) studies assume that therapeutic effects accrue from local myocardial effects of engrafted MSCs. Because few intravenously administered MSCs engraft in the myocardium, studies have mainly utilized d
Autor:
Nikolai Tankovich, Raymond J. Kim, Arshed A. Quyyumi, Robert T. Cole, Jane E. Wilcox, Sergey Sikora, Stephen E. Epstein, Javed Butler, Yi-An Ko, Stephen J. Greene, Allen S. Anderson, Kenneth B. Margulies, Michael J. Lipinski, Mihai Gheorghiade, Hal Skopicki
Publikováno v:
Circulation Research. 120:332-340
Rationale: Potential benefits of mesenchymal stem cell (MSC) therapy in heart failure may be related to paracrine properties and systemic effects, including anti-inflammatory activities. If this hypothesis is valid, intravenous administration of MSCs
Autor:
Stephen E. Epstein, Laurence S. Sperling, Nima Ghasemzadeh, Maria M. Brooks, Sergey Sikora, Helen Vlachos, Regina M. Hardison, Arshed A. Quyyumi
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background In a previous study, we found that a biomarker risk score ( BRS ) comprised of C‐reactive protein, fibrin‐degradation products, and heat shock protein‐70 predicts risk of myocardial infarction and death in coronary artery disease pat
Autor:
Danny J. Eapen, Salim S. Hayek, Nima Ghasemzadeh, Emir Veledar, Stephen E. Epstein, Pankaj Manocha, Yi-An Ko, A. Maziar Zafari, Tomasz Pielak, Sergey Sikora, Viola Vaccarino, Riyaz S. Patel, Dimitrios Kremastinos, Laurence S. Sperling, Stamatios Lerakis, Arshed A. Quyyumi, Christian W. Thorball, Hatem Al Kassem, Mohamed Khayata
Publikováno v:
Circulation: Cardiovascular Quality and Outcomes. 10
Background— Inflammation, coagulation, and cell stress contribute to atherosclerosis and its adverse events. A biomarker risk score (BRS) based on the circulating levels of biomarkers C-reactive protein, fibrin degradation products, and heat shock
Autor:
Stephen J. Greene, Hani N. Sabbah, Wilson S. Colucci, Frank Kramer, Christopher J. Larson, Raymond J. Kim, Javed Butler, Ramin V. Parsey, Mihai Gheorghiade, Lawrence I. Deckelbaum, James C. Carr, Michele Senni, Wilfried Dinh, Sanjiv J. Shah, Preston Dunnmon, John G.F. Cleland, Thomas Krahn, Shunichiro Okada, David Crandall, Norman Stockbridge, Stephen E. Epstein, Sergey Sikora, Karin Wåhlander
Publikováno v:
Circulation: Heart Failure. 9
Compared with heart failure (HF) care 20 to 30 years ago, there has been tremendous advancement in therapy for ambulatory HF with reduced ejection fraction with the use of agents that block maladaptive neurohormonal pathways. However, during the past
Autor:
Robert T. Cole, Mihai Gheorghiade, Nikolai Tankovich, Arshed A. Quyyumi, Sergey Sikora, Hal Skopicki, Stephen E. Epstein, Javed Butler, Raymond J. Kim, Jane E. Wilcox, Lev Verkh, Stephen J. Greene, Allen S. Anderson
Publikováno v:
Journal of cardiovascular medicine (Hagerstown, Md.). 18(4)
This article describes an ongoing study investigating the safety and efficacy of ischemia-tolerant mesenchymal stem cell (MSC) therapy in patients with nonischemic heart failure and dysfunctional viable myocardium without scarring. This study will fo
Autor:
Sergey Sikora, Ron Waksman, Stephen E. Epstein, David K. Glover, Dror Luger, Julien Dimastromatteo, Wei Sun, Michael J. Lipinski, David Hellinga
Publikováno v:
JACC: Cardiovascular Interventions. 8(2)
Intravenous delivery of MSCs for MI could have major clinical implications. Also, MSCs grown under chronic hypoxic conditions have attributes suggesting more robust healing and homing functions. Therefore, we studied whether human and murine hypoxic
Autor:
Vladimir S. Akatov, Albert G. Remacle, Martin Fugère, Alexei Y. Savinov, Alex Y. Strongin, Alexei V. Chekanov, Robert Day, Vladislav S. Golubkov, Dmitri V. Rozanov, Sergey Sikora
Publikováno v:
Archives of Biochemistry and Biophysics. 446:52-59
Anthrax toxin consists of protective antigen (PA), and lethal (LF) and edema (EF) factors. A 83 kDa PA monomer (PA83) precursor binds to the cell receptor. Furin-like proprotein convertases (PCs) cleave PA83 to generate cell-bound 63 kDa protein (PA6
Autor:
Adam Godzik, Sergey Sikora
Publikováno v:
Protein Science. 13:786-796
Using the tumor suppressor VHL protein as an example, we show that detailed analysis of conservation versus variation pattern in the multiple alignment can be coupled with the genomic pathway/complex conservation analysis to provide a more complete p