Výsledky vyhledávání - "Sergey S. Krylov"

Akademický článek

Triphenylphosphine Derivatives of Allylbenzenes Express Antitumor and Adjuvant Activity When Solubilized with Cyclodextrin-Based Formulations

Autor: Igor D. Zlotnikov, Sergey S. Krylov, Marina N. Semenova, Victor V. Semenov, Elena V. Kudryashova

Publikováno v: Pharmaceuticals, Vol 16, Iss 12, p 1651 (2023)

Allylbenzenes (apiol, dillapiol, myristicin and allyltetramethoxybenzene) are individual components of plant essential oils that demonstrate antitumor activity and can enhance the antitumor activity of cytotoxic drugs, such as paclitaxel, doxorubicin

Externí odkaz: https://doaj.org/article/beb66cf681ff46bbbf9adc957cf534f6

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Akademický článek

Covalent Conjugates of Allylbenzenes and Terpenoids as Antibiotics Enhancers with the Function of Prolonged Action

Autor: Igor D. Zlotnikov, Maria P. Davydova, Milan R. Danilov, Sergey S. Krylov, Natalya G. Belogurova, Elena V. Kudryashova

Publikováno v: Pharmaceuticals, Vol 16, Iss 8, p 1102 (2023)

The drug resistance of pathogenic bacteria is often due efflux pumps—specific proteins that remove foreign compounds from bacterial cells. To overcome drug resistance, adjuvants are often used that can inhibit efflux pumps or other systems that ens

Externí odkaz: https://doaj.org/article/d36481e58a7e48bea09f218f40a587cc

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Akademický článek

Polymeric Micelles Formulation of Combretastatin Derivatives with Enhanced Solubility, Cytostatic Activity and Selectivity against Cancer Cells

Autor: Igor D. Zlotnikov, Alexander A. Ezhov, Artem S. Ferberg, Sergey S. Krylov, Marina N. Semenova, Victor V. Semenov, Elena V. Kudryashova

Publikováno v: Pharmaceutics, Vol 15, Iss 6, p 1613 (2023)

Combretastatin derivatives is a promising class of antitumor agents, tubulin assembly inhibitors. However, due to poor solubility and insufficient selectivity to tumor cells, we believe, their therapeutic potential has not been fully realized yet. Th

Externí odkaz: https://doaj.org/article/6e6922294a3a4a97a452b198b5de7dc3

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Akademický článek

Plant Alkylbenzenes and Terpenoids in the Form of Cyclodextrin Inclusion Complexes as Antibacterial Agents and Levofloxacin Synergists

Autor: Igor D. Zlotnikov, Natalya G. Belogurova, Sergey S. Krylov, Marina N. Semenova, Victor V. Semenov, Elena V. Kudryashova

Publikováno v: Pharmaceuticals, Vol 15, Iss 7, p 861 (2022)

Allylpolyalkoxybenzenes (APABs) and terpenoids from plant essential oils exhibit a range of remarkable biological effects, including analgesic, antibacterial, anti-inflammatory, antioxidant, and others. Synergistic activity with antibiotics of differ

Externí odkaz: https://doaj.org/article/cc80768d3563491f9d6a554a37893a2b

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