Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Sergey S Larin"'
Autor:
Daniel V Kalinovsky, Alexey V Kibardin, Irina V Kholodenko, Elena V Svirshchevskaya, Igor I Doronin, Mariya V Konovalova, Maria V Grechikhina, Fedor N Rozov, Sergey S Larin, Sergey M Deyev, Roman V Kholodenko
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 6 (2022)
Externí odkaz:
https://doaj.org/article/07250ee509ce49b3a8f14a77f583361b
Autor:
Daniel V. Kalinovsky, Irina V. Kholodenko, Elena V. Svirshchevskaya, Alexey V. Kibardin, Dmitry Yu. Ryazantsev, Fedor N. Rozov, Sergey S. Larin, Sergey M. Deyev, Roman V. Kholodenko
Publikováno v:
Current Issues in Molecular Biology, Vol 45, Iss 10, Pp 8112-8125 (2023)
Oligomerization of antibody fragments via modification with polyethylene glycol (pegylation) may alter their function and properties, leading to a multivalent interaction of the resulting constructs with the target antigen. In a recent study, we gene
Externí odkaz:
https://doaj.org/article/bf8e0d4d6862409b924c8a06a327194f
Autor:
Vladimir V. Strelnikov, Ekaterina B. Kuznetsova, Alexander S. Tanas, Viktoria V. Rudenko, Alexey I. Kalinkin, Elena V. Poddubskaya, Tatiana V. Kekeeva, Galina G. Chesnokova, Ivan D. Trotsenko, Sergey S. Larin, Sergey I. Kutsev, Dmitry V. Zaletaev, Marina V. Nemtsova, Olga A. Simonova
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Cell transmembrane receptors and extracellular matrix components play a pivotal role in regulating cell activity and providing for the concerted integration of cells in the tissue structures. We have assessed DNA methylation in the promoter
Externí odkaz:
https://doaj.org/article/9674b2bcc0154773b10c7499d5ce84fc
Autor:
Liubov O. Skorodumova, Ksenia A. Davydenko, Alexandra Y. Filatova, Mikhail Yu Skoblov, Nikolay A. Kulemin, Maryam B. Khadzhieva, Elena S. Zakharova, Veronika D. Gordeeva, Nataliya S. Smetanina, Irina V. Fedyushkina, Lyudmila A. Anastasevich, Sergey S. Larin
Publikováno v:
Clinical Genetics. 103:93-96
Autor:
Maryam B. Khadzhieva, Ekaterina V. Kalinina, Sergey S. Larin, Daria A. Sviridova, Alesya S. Gracheva, Julia V. Chursinova, Vadim A. Stepanov, Ivan V. Redkin, Lyudmila S. Avdeikina, Alexander G. Rumyantsev, Artem N. Kuzovlev, Lyubov E. Salnikova
Publikováno v:
Diagnostics, Vol 11, Iss 8, p 1486 (2021)
COVID-19 patients with acute respiratory distress syndrome (ARDS) have an immune imbalance when systemic inflammation and dysfunction of circulating T and B cells lead to a more severe disease. Using TREC/KREC analysis, we studied the level of mature
Externí odkaz:
https://doaj.org/article/46e84088bed041c59782b981e2c10db8
Autor:
Anna A. Lobas, Elizaveta M. Solovyeva, Lev I. Levitsky, Anton O. Goncharov, Elena Y. Lyssuk, Sergey S. Larin, Sergei A. Moshkovskii, Mikhail V. Gorshkov
Publikováno v:
International Journal of Molecular Sciences
Volume 24
Issue 3
Pages: 2466
Volume 24
Issue 3
Pages: 2466
Alternative splicing is one of the main regulation pathways in living cells beyond simple changes in the level of protein expression. Most of the approaches proposed in proteomics for the identification of specific splicing isoforms require a prelimi
Autor:
Daniel V. Kalinovsky, Irina V. Kholodenko, Alexey V. Kibardin, Igor I. Doronin, Elena V. Svirshchevskaya, Dmitriy Y. Ryazantsev, Maria V. Konovalova, Fedor N. Rozov, Sergey S. Larin, Sergey M. Deyev, Roman V. Kholodenko
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 2; Pages: 1239
Ganglioside GD2 is a well-established target expressed on multiple solid tumors, many of which are characterized by low treatment efficiency. Antibody-drug conjugates (ADCs) have demonstrated marked success in a number of solid tumors, and GD2-direct
Autor:
Liubov O, Skorodumova, Ksenia A, Davydenko, Alexandra Y, Filatova, Mikhail Yu, Skoblov, Nikolay A, Kulemin, Maryam B, Khadzhieva, Elena S, Zakharova, Veronika D, Gordeeva, Nataliya S, Smetanina, Irina V, Fedyushkina, Lyudmila A, Anastasevich, Sergey S, Larin
Publikováno v:
Clinical geneticsREFERENCES. 103(1)
Diamond-Blackfan anemia (DBA) is an inherited bone marrow failure syndrome characterized by erythroid aplasia. Pathogenic variants in ribosomal protein (RP) genes, GATA1, TSR2, and EPO, are considered to be the etiology of DBA. Variants in 5'-untrans
Autor:
Irina V. Kholodenko, Daniel V. Kalinovsky, Elena V. Svirshchevskaya, Igor I. Doronin, Maria V. Konovalova, Alexey V. Kibardin, Tatyana V. Shamanskaya, Sergey S. Larin, Sergey M. Deyev, Roman V. Kholodenko
Publikováno v:
Molecules, Vol 24, Iss 21, p 3835 (2019)
Antigen-binding fragments of antibodies specific to the tumor-associated ganglioside GD2 are well poised to play a substantial role in modern GD2-targeted cancer therapies, however, rapid elimination from the body and reduced affinity compared to ful
Externí odkaz:
https://doaj.org/article/63d260e83a8b4c54842c491d2f1b4b63
Publikováno v:
Nucleic Acids Research
Operations with nucleic acids are among the main means of studying the mechanisms of gene function and developing novel methods of molecular medicine and gene therapy. These endeavours usually imply the necessity of nucleic acid storage and delivery