Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Sergey Pryshchep"'
Publikováno v:
Journal of Nanophotonics. 14:1
Stimulated emission depletion (STED), as one of the emerging super-resolution techniques, defines a state-of-the-art image resolution method. It has been developed into a universal fluorescent imaging tool over the past several years. The currently b
Autor:
Herman K. Lehman, Michael L. McCormick, M. Daben J. Libardo, Janet Hammer, Sophie E. Mayeux, Akritee Shrestha, Robert M. Hayden, Riqiang Fu, Alfredo M. Angeles-Boza, Sergey Pryshchep, Jack Blazyk, Mason Schoeneck, Bryan M. Ferguson, Myriam Cotten, Kimberly A. Bogardus, Gina K. Goldberg
Publikováno v:
The Journal of Physical Chemistry B. 119:15235-15246
Piscidins were the first antimicrobial peptides discovered in the mast cells of vertebrates. While two family members, piscidin 1 (p1) and piscidin 3 (p3), have highly similar sequences and α-helical structures when bound to model membranes, p1 gene
Autor:
Ellen B. Duffy, Sergey Pryshchep, Blanca Barquera, Henry D. Herce, Teri N. Hreha, Katherine G. Mezic, Anais Bourges, Oscar Juárez
Publikováno v:
Biochemistry. 54:2443-2455
RNF is a redox-driven ion (Na(+) and in one case possibly H(+)) transporter present in many prokaryotes. It has been proposed that RNF performs a variety of reactions in different organisms, delivering low-potential reducing equivalents for specific
Publikováno v:
The Journal of Immunology. 193:68-76
T cell activation by Ag is one of the key events in adaptive immunity. It is triggered by interactions of the TCR and coreceptor (CD8 or CD4) with antigenic peptides embedded in MHC (pMHC) molecules expressed on APCs. The mechanism of how signal is i
Autor:
Jörg J. Goronzy, Christine Konya, Masakatsu Suzuki, Cornelia M. Weyand, Sergey Pryshchep, Ann Jagger, Yasuhiro Shimojima
Publikováno v:
The Journal of Immunology. 189:2118-2130
CD8 T cells stimulated with a suboptimal dose of anti-CD3 Abs (100 pg/ml) in the presence of IL-15 retain a naive phenotype with expression of CD45RA, CD28, CD27, and CCR7 but acquire new functions and differentiate into immunosuppressive T cells. CD
Publikováno v:
Clinical Immunology. 143:73-82
In rheumatoid arthritis (RA), hematopoietic progenitor cells (HPC) have age-inappropriate telomeric shortening suggesting premature senescence and possible restriction of proliferative capacity. In response to hematopoietic growth factors RA-derived
Autor:
Lu Tian, Mingcan Yu, David L. Lamar, Deepak Tomar, Marta Czesnikiewicz-Guzik, Karnail Singh, Cornelia M. Weyand, Guangjin Li, Sergey Pryshchep, Won Woo Lee, Jörg J. Goronzy
Publikováno v:
The Journal of Experimental Medicine
Zinc enhances TCR signaling in part by inhibiting Shp-1 recruitment to the TCR synapse.
Zinc is a trace element that is essential for innate and adaptive immune responses. In addition to being a structural element of many proteins, zinc also fun
Zinc is a trace element that is essential for innate and adaptive immune responses. In addition to being a structural element of many proteins, zinc also fun
Publikováno v:
Circulation Research. 106:769-778
Rationale : In the vulnerable atherosclerotic plaque, T cells may destabilize the tissue structure through direct cell-injurious effector functions. T cells transmit environmental signals, such as recognition of antigen, into cellular responses throu
Autor:
Sergey Pryshchep, Jörg J. Goronzy, Pratima Deshpande, Ines Colmegna, Vladimir M. Liarski, Karnail Singh, Cornelia M. Weyand
Publikováno v:
The Journal of Immunology. 183:8258-8267
Immune responses to citrullinated neoantigens and clinical efficacy of costimulation blockade indicate a general defect in maintaining T cell tolerance in rheumatoid arthritis (RA). To examine whether TCR threshold calibration contributes to disease
Autor:
Sergey Pryshchep, Karnail Singh, Jörg J. Goronzy, Hirokazu Sawai, Gabriella Henel, Eun Bong Lee, Cornelia M. Weyand
Publikováno v:
Annals of the New York Academy of Sciences. 1062:182-194
The pathogenesis of rheumatoid arthritis (RA) is determined by a complex interaction of genetic and environmental factors. Of all risk factors, age has the largest impact. RA occurs most often during the postmenopausal period of life, with incidence