Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Sergey Parfenyev"'
Autor:
Alexandra Daks, Sergey Parfenyev, Oleg Shuvalov, Olga Fedorova, Alexander Nazarov, Gerry Melino, Nickolai A. Barlev
Publikováno v:
Biology Direct, Vol 19, Iss 1, Pp 1-16 (2024)
Abstract The enzymes performing protein post-translational modifications (PTMs) form a critical post-translational regulatory circuitry that orchestrates literally all cellular processes in the organism. In particular, the balance between cellular st
Externí odkaz:
https://doaj.org/article/30065b6fd84e42a1a68323da3829130e
Autor:
Oleg Shuvalov, Yulia Kirdeeva, Alexandra Daks, Olga Fedorova, Sergey Parfenyev, Hans-Uwe Simon, Nickolai A. Barlev
Publikováno v:
Antioxidants, Vol 12, Iss 11, p 2012 (2023)
Cancer metabolic reprogramming is a complex process that provides malignant cells with selective advantages to grow and propagate in the hostile environment created by the immune surveillance of the human organism. This process underpins cancer proli
Externí odkaz:
https://doaj.org/article/03d1055ade09473483a8e003b0c47098
Autor:
Oleg Shuvalov, Yulia Kirdeeva, Elizaveta Fefilova, Sofia Netsvetay, Mark Zorin, Yulia Vlasova, Olga Fedorova, Alexandra Daks, Sergey Parfenyev, Nickolai Barlev
Publikováno v:
Metabolites, Vol 13, Iss 5, p 656 (2023)
20-Hydroxyecdysone (20E) is an arthropod hormone which is synthesized by some plants as part of their defense mechanism. In humans, 20E has no hormonal activity but possesses a number of beneficial pharmacological properties including anabolic, adapt
Externí odkaz:
https://doaj.org/article/ecbd015095914a1f95105465f923e5fc
Autor:
Sergey Parfenyev, Aastha Singh, Olga Fedorova, Alexandra Daks, Ritu Kulshreshtha, Niсkolai A. Barlev
Publikováno v:
Cell Death and Disease, Vol 12, Iss 1, Pp 1-16 (2021)
Abstract The epithelial–mesenchymal transition (EMT) plays a pivotal role in the differentiation of vertebrates and is critically important in tumorigenesis. Using this evolutionarily conserved mechanism, cancer cells become drug-resistant and acqu
Externí odkaz:
https://doaj.org/article/467e36cd6f454e3abca0971ae81bdcf5
Autor:
Alexandra Daks, Olga Fedorova, Sergey Parfenyev, Ivan Nevzorov, Oleg Shuvalov, Nickolai A. Barlev
Publikováno v:
Cells, Vol 11, Iss 9, p 1515 (2022)
The p53-dependent ubiquitin ligase Pirh2 regulates a number of proteins involved in different cancer-associated processes. Targeting the p53 family proteins, Chk2, p27Kip1, Twist1 and others, Pirh2 participates in such cellular processes as prolifera
Externí odkaz:
https://doaj.org/article/ac03877e1de1436b9688df28037ca8c7
Autor:
Julia Vasileva, Sofia Netsvetay, Sergey Parfenyev, Nikolai A. Barlev, Oleg Semyonov, Alexandra Daks, Olga A. Fedorova, Oleg Shuvalov, Nurken Berdigaliyev, Alexey Petukhov, Vasilii Golotin, Anastasia Gudovich, Ekaterina Baiduik, Eugene Tulchinsky
Publikováno v:
Biochemical and Biophysical Research Communications. 589:29-34
Autophagy is a highly conserved process of cellular self-digestion that involves the formation of autophagosomes for the delivery of intracellular components and dysfunctional organelles to lysosomes. This process is induced by different signals incl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4dc8a5b6b5921e5984bbf607dfe3fad
https://doi.org/10.1016/j.bbrc.2021.11.088
https://doi.org/10.1016/j.bbrc.2021.11.088
Autor:
Alena Kizenko, Victoria Mamontova, Sergey Parfenyev, Olga A. Fedorova, Nickolai A. Barlev, Alexandra Daks, Aigul R. Venina, Oleg Shuvalov, Alexey Petukhov, Sofia Netsvetay, Evgeny N. Imyanitov
Publikováno v:
Biochemical and Biophysical Research Communications. 572:41-48
The SET domain containing lysine-specific methyltransferase, Set7/9, covalently attaches methyl moieties to a variety of histone and non-histone substrates. Among the substrates of Set7/9 are: p53, NF-kB, PARP1, E2F1, and other transcription factors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbb241844d00e77207d9208d5d05c3e0
https://doi.org/10.1016/j.bbrc.2021.07.086
https://doi.org/10.1016/j.bbrc.2021.07.086
Autor:
Oleg Shuvalov, Sergey Parfenyev, Anastasia Gudovich, Alexandra Daks, Olga A. Fedorova, Alexey Petukhov, Alena Kizenko, E. V. Baidyuk, Nikolai A. Barlev
Publikováno v:
Biochemical and Biophysical Research Communications. 563:119-125
Autophagy is a special catabolic cellular program that is induced in response to deprivation of nutrients and energy starvation. During the execution of this program, cellular components, including aggregates, as well as damaged organelles and some p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::795de9d30579118211a9304264d60a93
https://doi.org/10.1016/j.bbrc.2021.05.024
https://doi.org/10.1016/j.bbrc.2021.05.024
Publikováno v:
Cancers. 14:3786
Phosphatase and Tensin Homolog deleted on Chromosome 10 (PTEN) is one of the critical tumor suppressor genes and the main negative regulator of the PI3K pathway. PTEN is frequently found to be inactivated, either partially or fully, in various malign
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39faba3daa64ecce5f192bd0703376ff
https://doi.org/10.3390/cancers14153786
https://doi.org/10.3390/cancers14153786
Autor:
Sergey Parfenyev, Aastha Singh, Olga A. Fedorova, Alexandra Daks, Ritu Kulshreshtha, Niсkolai A Barlev
Publikováno v:
Cell Death & Disease
Cell Death and Disease, Vol 12, Iss 1, Pp 1-16 (2021)
Cell Death and Disease, Vol 12, Iss 1, Pp 1-16 (2021)
The epithelial–mesenchymal transition (EMT) plays a pivotal role in the differentiation of vertebrates and is critically important in tumorigenesis. Using this evolutionarily conserved mechanism, cancer cells become drug-resistant and acquire the a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f61303a2c12f93b6fe9dd149ab1319b
https://pubmed.ncbi.nlm.nih.gov/33414456
https://pubmed.ncbi.nlm.nih.gov/33414456