Zobrazeno 1 - 10
of 95
pro vyhledávání: '"Sergey N. Shurov"'
Autor:
O. N. Oktyabr’skii, M. S. Danchuk, S. S. Zykova, A. P. Chernobrovkina, M. A. Kokhanov, I. A. Rodin, G. V. Smirnova, K. V. Bezmaternykh, A. G. Koshchaev, Sergey N. Shurov
Publikováno v:
Pharmaceutical Chemistry Journal. 54:777-780
The hepatoprotective activity of 8,8-dimethyl-5-p-tolyl-3,4,7,8-tetrahydro-2H-pyrido[4,3,2-de]cinnolin-3-one was studied in vivo using a model of CCl4-induced acute toxic hepatitis. It was found that this compound affected indices determining the lev
Publikováno v:
Radiochemistry. 62:101-106
A study of ion-molecular reactions of fluoro-substituted phenyl cations with benzopyridine derivatives demonstrated the following: (a) at present only the nuclear-chemical method enables the reaction of a direct phenylation of the nitrogen atom in be
Autor:
E. A. Nikiforova, Nikolay F. Kirillov, Dmitry P. Zverev, Sergey N. Shurov, Maksim V. Dmitriev
Publikováno v:
Chemistry of Heterocyclic Compounds. 57:92-94
The reactions of 1-benzoyl-2,4-diphenyl-2,3-dihydro-1H-1,5-benzodiazepine with methyl 1-bromocycloalkanecarboxylates and zinc, followed by hydrolysis of the reaction mixtures, resulted in the formation of spiro-δ-lactams bearing a 2-(N-benzoylamino)
Publikováno v:
Radiochimica Acta. 108:105-111
Quinazoline derivatives are well known to have a diverse array of therapeutic activities. Unfortunately, “classic” chemical synthesis does not provide an opportunity for the formation of N-phenyl quaternary 1,3-diazinium compounds. A devised nucl
Autor:
E. A. Nikiforova, Nikolay F. Kirillov, Sergey N. Shurov, Maksim V. Dmitriev, D. V. Baibarodskikh
Publikováno v:
Russian Journal of Organic Chemistry. 55:339-344
Reformatsky reaction of methyl 1-bromocyclopentanecarboxylate with 1-aryl-3-(2-hydroxyphenyl)-prop-2-en-1-ones afforded 6-substituted 4-(2-aryl-2-oxoethyl)-2H,4H-spiro[chromene-3,1′-cyclopentan]-2-ones. A probable reaction mechanism was proposed on
Publikováno v:
Russian Journal of Organic Chemistry. 54:573-577
Ethyl 2-amino-5-(2-aryl-2-oxoethylidene)-4-oxo-1H-4,5-dihydrofuran-3-carboxylates and 2-amino- 5-(2-aryl-2-oxoethylidene)-4-oxo-1H-4,5-dihydrofuran-3-carbonitriles reacted with alcohols in the presence of a catalytic amount of concentrated aqueous HC
Publikováno v:
Radiochemistry. 59:297-300
The developed nuclear-chemical method allows direct phenylation of the nitrogen atom in the isoquinoline molecule and one-step synthesis of tritium-labeled biomarkers containing previously unknown N-(p-difluorophenyl)isoquinolinium fragment with high
Autor:
K. O. Manylova, L. G. Chekanova, A. N. Vasyanin, O. A. Maiorova, Sergey N. Shurov, P. T. Pavlov
Publikováno v:
Russian Journal of General Chemistry. 87:414-419
Physicochemical properties of 4,5-(aryl, alkyl)-3-substituted 2-sulfonylaminothiophenes have been studied. The effect of the nature of the substituents in the thiophene ring on acid-base properties, solubility, and chemical stability was investigated
Publikováno v:
Russian Journal of Organic Chemistry. 52:848-856
2-(Arylimino)-5-(het)arylfuran-3(2H)-ones were synthesized by reaction of 5-(het)arylfuran-2,3-diones with N-(triphenyl-λ5-phosphanylidene)anilines, and their aminolysis afforded N-aryl-4-amino-4-(het)aryl-2-oxobut-3-enamides.
Autor:
N. E. Shchepina, I. M. Agafonova, G. A. Badun, A. N. Vasyanin, V. V. Avrorin, Sergey N. Shurov
Publikováno v:
Chemistry of Heterocyclic Compounds. 50:1595-1601
The use of nuclear-chemical synthesis, based on the generation of free nucleogenic phenyl cations, allowed for the direct phenylation of the nitrogen atom in 1,4-diazines. The presence of two methyl substituents in the quinoxaline substrate leads to