Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Sergey N. Lavrenov"'
Autor:
Igor B. Levshin, Alexander Y. Simonov, Sergey N. Lavrenov, Alexey A. Panov, Natalia E. Grammatikova, Alexander A. Alexandrov, Eslam S. M. O. Ghazy, Nikita A. Savin, Peter V. Gorelkin, Alexander S. Erofeev, Vladimir I. Polshakov
Publikováno v:
Pharmaceuticals, Vol 15, Iss 5, p 563 (2022)
Novel derivatives of Mycosidine (3,5-substituted thiazolidine-2,4-diones) are synthesized by Knoevenagel condensation and reactions of thiazolidines with chloroformates or halo-acetic acid esters. Furthermore, 5-Arylidene-2,4-thiazolidinediones and t
Externí odkaz:
https://doaj.org/article/2f7f303cc2264d6282e8aece6f627613
Autor:
Alexey S. Trenin, Elena B. Isakova, Michael I. Treshchalin, Vasilisa A. Polozkova, Elena P. Mirchink, Alexey A. Panov, Alexander Y. Simonov, Olga P. Bychkova, Victor V. Tatarskiy, Sergey N. Lavrenov
Publikováno v:
Pharmaceuticals, Vol 15, Iss 2, p 118 (2022)
The antimicrobial activity and toxicity of three novel synthetic antibacterial agents containing tris(1H-indol-3-yl)methylium fragment were studied in vitro and in vivo. All compounds in vitro revealed high activity (minimal inhibitory concentration
Externí odkaz:
https://doaj.org/article/bca3f521e64443ccbe39cf083d78031c
Autor:
Sergey N. Lavrenov, Elena B. Isakova, Alexey A. Panov, Alexander Y. Simonov, Viktor V. Tatarskiy, Alexey S. Trenin
Publikováno v:
Pharmaceuticals, Vol 13, Iss 12, p 469 (2020)
The wide spread of pathogens resistance requires the development of new antimicrobial agents capable of overcoming drug resistance. The main objective of the study is to elucidate the effect of substitutions in tris(1H-indol-3-yl)methylium derivative
Externí odkaz:
https://doaj.org/article/badb3b80ee774653b183ae99de2d512d
Publikováno v:
Pharmaceutical Chemistry Journal. 54:1263-1268
A new optimal synthetic scheme for new antibacterial compounds combining tris-(1-alkyindol-3-yl)methylium and 3-(indol-1-yl)maleimide in their structures was developed. The proposed method provided a significant increase in the product yield, reduced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e6706b58cb818f3aa4d20977b133812f
https://doi.org/10.1007/s11094-021-02352-w
https://doi.org/10.1007/s11094-021-02352-w
Autor:
Alexey S Trenin, Lyubov G. Dezhenkova, Olga P. Bychkova, Arthur S. Mkrtchyan, Victor V. Tatarskiy, Elena A. Tsvigun, Sergey N. Lavrenov
Publikováno v:
Chemistry of Heterocyclic Compounds. 56:741-746
A series of 3,3-bis(indol-3-yl)-1,3-dihydroindol-2-ones containing substituents at different positions of the oxindole ring were synthesized to study the effect of the position of the substituent on biological activity. Some of the new derivatives sh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be6bd3a1105ac82a0e17893246b0cce3
https://doi.org/10.1007/s10593-020-02725-1
https://doi.org/10.1007/s10593-020-02725-1
Autor:
Alexey S, Trenin, Elena B, Isakova, Michael I, Treshchalin, Vasilisa A, Polozkova, Elena P, Mirchink, Alexey A, Panov, Alexander Y, Simonov, Olga P, Bychkova, Victor V, Tatarskiy, Sergey N, Lavrenov
Publikováno v:
Pharmaceuticals (Basel, Switzerland). 15(2)
The antimicrobial activity and toxicity of three novel synthetic antibacterial agents containing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e5052a5771738042723ac4c5748b60db
https://pubmed.ncbi.nlm.nih.gov/35215231
https://pubmed.ncbi.nlm.nih.gov/35215231
Autor:
Alexey A, Panov, Sergey N, Lavrenov, Elena P, Mirchink, Elena B, Isakova, Alexander M, Korolev, Alexey S, Trenin
Publikováno v:
The Journal of antibiotics. 74(3)
A series of new compounds-arylbis(indol-3-yl)methylium derivatives-were synthesized and their antimicrobial activity was evaluated. All the compounds turned out to be highly active, with MIC depending on their structure and the length of N-alkyl resi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bd5f54b5fb5129c008a16e34b8232b24
https://pubmed.ncbi.nlm.nih.gov/33318623
https://pubmed.ncbi.nlm.nih.gov/33318623
Autor:
M. B. Nawrozkij, Konstantin V. Balakin, Ivan A. Novakov, Sergey N. Lavrenov, Rosanna Filosa, Arthur S. Mkrtchyan
Publikováno v:
Russian Chemical Reviews. 87:509-552
The present review is concerned with the synthesis and structure–activity relationship studies of Arbidol and its structural analogues. The latter are roughly divided into several unequal parts: indole- and benzofuran-based compounds, benzimidazole
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::92ceaa0357c30a6ae7cec6d827f1db25
https://doi.org/10.1070/rcr4791
https://doi.org/10.1070/rcr4791
Autor:
Sergey N. Lavrenov, Alexey A. Panov, Alexey S. Trenin, Sergey A. Lakatosh, Alexander Y. Simonov
Publikováno v:
Chemistry of Heterocyclic Compounds. 54:103-113
This review is devoted to methods for the synthesis of 3,4-disubstituted maleimides – compounds that often show pronounced biological activity. We offer classification of synthetic methods, present comparative analysis of various approaches while d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7457dd1a66bae61517b7617c8b51edeb
https://doi.org/10.1007/s10593-018-2240-z
https://doi.org/10.1007/s10593-018-2240-z
Autor:
Sergey N. Lavrenov, Alexander Y. Simonov, Alexey A. Panov, Alexey S Trenin, Elena B. Isakova, Elena P. Mirchink
Publikováno v:
The Journal of Antibiotics. 72:122-124
A series of 3,4-bis(arylthio)maleimides were synthesized and their antimicrobial activity was evaluated against Gram-positive and Gram-negative bacteria, including multidrug resistant (MDR) strains and some fungi. Most compounds turned out to be high
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::833a835b8f0efa27266c3bdcec15c92c
https://doi.org/10.1038/s41429-018-0122-3
https://doi.org/10.1038/s41429-018-0122-3