Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Sergey N. Cherenkevich"'
Autor:
Irina V. Gorudko, Alexey V. Sokolov, Ekaterina V. Shamova, Natalia A. Grudinina, Elizaveta S. Drozd, Ludmila M. Shishlo, Daria V. Grigorieva, Sergey B. Bushuk, Boris A. Bushuk, Sergey A. Chizhik, Sergey N. Cherenkevich, Vadim B. Vasilyev, Oleg M. Panasenko
Publikováno v:
Biology Open, Vol 2, Iss 9, Pp 916-923 (2013)
Summary Myeloperoxidase (MPO) is a heme-containing enzyme released from activated leukocytes into the extracellular space during inflammation. Its main function is the production of hypohalous acids that are potent oxidants. MPO can also modulate cel
Externí odkaz:
https://doaj.org/article/57d7fb52d176437bb4ce72c69775a296
Autor:
Maryna A. Hliatsevich, Pavel M. Bulai, Taras N. Pitlik, Andrey A. Denisov, Sergey N. Cherenkevich
Publikováno v:
Mathematical Modelling and Analysis, Vol 20, Iss 1 (2015)
Mathematical model describing signal transduction between neurons has been presented using the system of nonlinear ordinary differential equations. The Cauchy problem for the given system has been solved numerically and system parameters were adjuste
Externí odkaz:
https://doaj.org/article/45d270d3dd404a2cad540ffdab4412a9
Autor:
Alexey V. Sokolov, I. V. Borodina, D. S. Matyushkina, Sergey N. Cherenkevich, Daria V. Grigorieva, I. V. Gorudko, Oleg M. Panasenko, V. E. Reut, V. A. Ivanov
Publikováno v:
Russian Journal of Bioorganic Chemistry. 47:299-306
The interaction of the oxazine dye gallocyanine with reactive oxygen ( $$^{\centerdot }{\text{O}}_{2}^{ - },$$ Н2О2) and halogen (HOCl) species has been studied by spectrophotometry, mass spectrometry, and spectrofluorimetry. It has been shown that
Autor:
Sergey N. Cherenkevich, E. B. Menshchikova, G. G. Martinovich, N. K. Zenkov, I. V. Martinovich, A. V. Vcherashniaya
Publikováno v:
Biophysics. 65:920-930
Pharmacological modification of the redox properties of tumor cells is a promising approach to enhance the efficiency of antitumor therapy. The Nrf2 transcription factor is considered as a new target for the development of selective chemosensitizers.
Autor:
I. V. Martinovich, A. V. Vcherashniaya, Sergey N. Cherenkevich, Oleg I. Shadyro, G. G. Martinovich
Publikováno v:
Journal of Applied Spectroscopy. 87:515-519
Fluorescence assay and Raman spectroscopy were used to study the mechanisms of action of 2-isopropyl-5-methyl- 1,4-benzoquinone (thymoquinone) on HEp-2 human larynx carcinoma cells. Thymoquinone was found to have a more pronounced toxic effect than 1
Autor:
Nikolay N. Gorbunov, Valeria A. Kostevich, Veronika E. Lutsenko, Daria V. Grigorieva, Alexey V. Sokolov, Sergey N. Cherenkevich, I. V. Gorudko, Oleg M. Panasenko
Publikováno v:
Medical academic journal. 19:63-71
Objective — the study of hypochlorous acid (HOCl) and its derivatives production, which catalyzed by human neutrophil myeloperoxidase, using “turn-on” fluorescent sensor — celestine blue B. Materials and methods. Neutrophils were isolated fro
Autor:
Elena D. Syromiatnikova, Ekaterina V. Shamova, Sergey N. Cherenkevich, Alexey V. Sokolov, Vadim B. Vasilyev, I. V. Gorudko, Igor Kudryavtsev, Oleg M. Panasenko, Valeria A. Kostevich, Daria V. Grigorieva
Publikováno v:
Biochemistry and Cell Biology. 96:592-601
Myeloperoxidase (MPO) is an oxidant-producing enzyme that can also regulate cellular functions via its nonenzymatic effects. Mature active MPO isolated from normal human neutrophils is a 145 kDa homodimer, which consists of 2 identical protomers, con
Autor:
Alexey V. Sokolov, Sergey N. Cherenkevich, Vassili N. Lazarev, T. V. Vakhrusheva, Daria V. Grigorieva, Oleg M. Panasenko, I. V. Gorudko, Vadim B. Vasilyev, Valeria A. Kostevich
Publikováno v:
Biochemistry and Cell Biology. 96:580-591
Myeloperoxidase (MPO), found mainly in neutrophils, is released in inflammation. MPO produces reactive halogen species (RHS), which are bactericidal agents. However, RHS overproduction, i.e., halogenative stress, can also damage host biomolecules, an
Autor:
Darya Grigoryeva, Sergey N. Cherenkevich, I. V. Gorudko, O. M. Panasenko, A V Sokolov, Veronika E. Lutsenko
Publikováno v:
Vestnik Volgogradskogo Gosudarstvennogo Universiteta. Serija 11. Estestvennye nauki. :44-48
The development of adequate methods for monitoring the functional state of neutrophils is an urgent task due to their important role in the development of the inflammatory response. In this study, the functional activity of neutrophils has been asses
Autor:
E. V. Mikhalchik, Stanislav O. Kozlov, Juergen Arnhold, Michael V. Filatov, Elena Yu. Varfolomeeva, Vadim B. Vasilyev, Alexey V. Sokolov, Daria V. Grigorieva, Igor Kudryavtsev, Oleg M. Panasenko, I. V. Gorudko, Valeria A. Kostevich, Sergey N. Cherenkevich
Publikováno v:
Biochemistry and Cell Biology. 96:457-467
CP is a copper-containing ferroxidase of blood plasma, which acts as an acute phase reactant during inflammation. The effect of oxidative modification of CP induced by oxidants produced by MPO, such as HOCl, HOBr, and HOSCN, on its spectral, enzymati