Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Sergey N Fedosov"'
Autor:
Evelyne Furger, Sergey N Fedosov, Dorte Launholt Lildballe, Robert Waibel, Roger Schibli, Ebba Nexo, Eliane Fischer
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e37421 (2012)
Haptocorrin (HC) is a circulating corrinoid binding protein with unclear function. In contrast to transcobalamin, the other transport protein in blood, HC is heavily glycosylated and binds a variety of cobalamin (Cbl) analogues. HC is present not onl
Externí odkaz:
https://doaj.org/article/e746c69532c449408e881ca48d381e85
Publikováno v:
Food Chemistry: X, Vol 19, Iss , Pp 100824- (2023)
Inactive analogues of vitamin B12 (cobalamin, Cbl) can mimic the active Cbl in food if using the traditional microbiological measurements. Thus, overestimated Cbl was recently revealed in edible insects employing immunoaffinity adsorption, HPLC-separ
Externí odkaz:
https://doaj.org/article/93e70591ab8d47af852f336b44227bde
Publikováno v:
Fedosov, S, Nexø, E & Würtz Heegaard, C 2023, ' Low methylcobalamin in liver tissues is an artifact as shown by a revised extraction procedure. ', Biochimica et Biophysica Acta (BBA)-General Subjects, vol. 1867, no. 4, 130315 . https://doi.org/10.1016/j.bbagen.2023.130315
Background: Vitamin B12 (cobalamin, Cbl) is represented by several molecular variants distinguished by the exchangeable ligand X coordinated to cobalt ion (XCbl). The most typical XCbl-forms are cyanocobalamin (CNCbl), hydroxocobalamin (HOCbl), methy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2995ae533dfb8e2fa2918c6d86c61b77
https://pure.au.dk/portal/da/publications/low-methylcobalamin-in-liver-tissues-is-an-artifact-as-shown-by-a-revised-extraction-procedure(15c94af6-fae2-438f-a204-a7ce035bb2c6).html
https://pure.au.dk/portal/da/publications/low-methylcobalamin-in-liver-tissues-is-an-artifact-as-shown-by-a-revised-extraction-procedure(15c94af6-fae2-438f-a204-a7ce035bb2c6).html
Autor:
Sergey N. Fedosov, Josef Geryk, Dana Kučerová, Markéta Reinišová, Cyril Bařinka, Jiří Hejnar, Jana Mikešová, Jan Kosla, Veronika Krchlíková, Daniel Elleder, Ebba Nexo
Publikováno v:
J Virol
Krchlíková, V, Mikešová, J, Geryk, J, Bařinka, C, Nexo, E, Fedosov, S N, Kosla, J, Kučerová, D, Reinišová, M, Hejnar, J & Elleder, D 2021, ' The avian retroviral receptor tva mediates the uptake of transcobalamin bound vitamin B 12 (Cobalamin) ', Journal of Virology, vol. 95, no. 8, e02136-20 . https://doi.org/10.1128/JVI.02136-20
Krchlíková, V, Mikešová, J, Geryk, J, Bařinka, C, Nexo, E, Fedosov, S N, Kosla, J, Kučerová, D, Reinišová, M, Hejnar, J & Elleder, D 2021, ' The avian retroviral receptor tva mediates the uptake of transcobalamin bound vitamin B 12 (Cobalamin) ', Journal of Virology, vol. 95, no. 8, e02136-20 . https://doi.org/10.1128/JVI.02136-20
The avian sarcoma and leukosis viruses (ASLVs) are important chicken pathogens. Some of the virus subgroups, including ASLV-A and K, utilize the Tva receptor for cell entrance. Though Tva was identified 3 decades ago, its physiological function remai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3216ce3000b5c168fb1a87265a036e4b
https://pubmed.ncbi.nlm.nih.gov/33504597
https://pubmed.ncbi.nlm.nih.gov/33504597
Autor:
Julia Hinkel, Johannes Schmitt, Michael Wurm, Stefanie Rosenbaum-Fabian, Karl Otfried Schwab, Donald W. Jacobsen, Ute Spiekerkoetter, Sergey N. Fedosov, Luciana Hannibal, Sarah C. Grünert
Publikováno v:
Journal of Clinical Medicine
Hinkel, J, Schmitt, J, Wurm, M, Rosenbaum-Fabian, S, Schwab, K O, Jacobsen, D W, Spiekerkoetter, U, Fedosov, S N, Hannibal, L & Gruenert, S C 2020, ' Elevated Plasma Vitamin B(12) in Patients with Hepatic Glycogen Storage Diseases ', Journal of Clinical Medicine, vol. 9, no. 8, 2326 . https://doi.org/10.3390/jcm9082326
Volume 9
Issue 8
Journal of Clinical Medicine, Vol 9, Iss 2326, p 2326 (2020)
Hinkel, J, Schmitt, J, Wurm, M, Rosenbaum-Fabian, S, Schwab, K O, Jacobsen, D W, Spiekerkoetter, U, Fedosov, S N, Hannibal, L & Gruenert, S C 2020, ' Elevated Plasma Vitamin B(12) in Patients with Hepatic Glycogen Storage Diseases ', Journal of Clinical Medicine, vol. 9, no. 8, 2326 . https://doi.org/10.3390/jcm9082326
Volume 9
Issue 8
Journal of Clinical Medicine, Vol 9, Iss 2326, p 2326 (2020)
Background: Hepatic glycogen storage diseases (GSDs) are inborn errors of metabolism affecting the synthesis or breakdown of glycogen in the liver. This study, for the first time, systematically assessed vitamin B12 status in a large cohort of hepati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::91dca4929ceac8a27b465004b3ffb1fc
http://europepmc.org/articles/PMC7463656
http://europepmc.org/articles/PMC7463656
Autor:
Linda Skibsted Kornerup, Sergey N. Fedosov, Christian W. Heegaard, Christian B. Juul, Ebba Nexo, Eva Greibe
Publikováno v:
Greibe, E, Kornerup, L S, Juul, C B, Fedosov, S, Heegaard, C W & Nexø, E 2018, ' The tissue profile of metabolically active coenzyme forms of vitamin B12 differs in vitamin B12-depleted rats treated with hydroxo-B12 or cyano-B12 ', British Journal of Nutrition, vol. 120, pp. 49-56 . https://doi.org/10.1017/S000711451800123X
Recent rat studies show different tissue distributions of vitamin B12 (B12), administered orally as hydroxo-B12 (HO-B12) (predominant in food) and cyano-B12 (CN-B12) (common in supplements). Here we examine male Wistar rats kept on a low-B12 diet for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::116eab7ea93262d1599a2e4a49e0e532
https://doi.org/10.1017/s000711451800123x
https://doi.org/10.1017/s000711451800123x
Publikováno v:
Mutti, E, Hunger, M, Fedosov, S, Nexo, E & Kräutler, B 2017, ' Organometallic DNA–B 12 Conjugates as Potential Oligonucleotide Vectors : Synthesis and Structural and Binding Studies with Human Cobalamin-Transport Proteins ', ChemBioChem, vol. 18, no. 22, pp. 2280-2291 . https://doi.org/10.1002/cbic.201700472
The synthesis and structural characterization of Co-(dN)25-Cbl (Cbl: cobalamin; dN: deoxynucleotide) and Co-(dN)39-Cbl, which are organometallic DNA–B12 conjugates with single DNA strands consisting of 25 and 39 deoxynucleotides, respectively, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed621c74e9b3b7faa19d8b09895944fb
https://doi.org/10.1002/cbic.201700472
https://doi.org/10.1002/cbic.201700472
Autor:
Ebba Nexo, Eva Greibe, Christian W. Heegaard, Linda Skibsted Kornerup, Christian B. Juul, Sergey N. Fedosov
Publikováno v:
European Journal of Nutrition
Kornerup, L S, Fedosov, S, Juul, C B, Greibe, E, Heegaard, C W & Nexø, E 2018, ' Tissue distribution of oral vitamin B12 is influenced by B12 status and B12 form: an experimental study in rats ', European Journal of Nutrition, vol. 57, no. 4, 4, pp. 1459-1469 . https://doi.org/10.1007/s00394-017-1424-0
Kornerup, L S, Fedosov, S, Juul, C B, Greibe, E, Heegaard, C W & Nexø, E 2018, ' Tissue distribution of oral vitamin B12 is influenced by B12 status and B12 form: an experimental study in rats ', European Journal of Nutrition, vol. 57, no. 4, 4, pp. 1459-1469 . https://doi.org/10.1007/s00394-017-1424-0
Purpose Hydroxocobalamin (HOCbl) is the dominating Cbl form in food, whereas cyanocobalamin (CNCbl) is common in vitamin pills and oral supplements. This study compares single-dose absorption and distribution of oral HO[57Co]Cbl and CN[57Co]Cbl in Cb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4756832b50fc6c45254e02ad2c099ca0
http://europepmc.org/articles/PMC5960002
http://europepmc.org/articles/PMC5960002
Autor:
Marie Stampe Ostenfeld, Sergey N. Fedosov, Sadanand S Naik, Namita Mahalle, Eva Greibe, Ebba Nexo, Christian W. Heegaard
Publikováno v:
Naik, S, Mahalle, N, Greibe, E, Ostenfeld, M, Heegaard, C W, Nexø, E & Fedosov, S 2019, ' Cyano-B12 or Whey Powder with Endogenous Hydroxo-B12 for Supplementation in B12 Deficient Lactovegetarians ', Nutrients, vol. 11, no. 10, 2382 . https://doi.org/10.3390/nu11102382
Nutrients
Nutrients, Vol 11, Iss 10, p 2382 (2019)
Volume 11
Issue 10
Nutrients
Nutrients, Vol 11, Iss 10, p 2382 (2019)
Volume 11
Issue 10
Lactovegetarians (n = 35) with low vitamin B12 (B12) status were intervened for eight weeks capsules containing cyano-B12 (CN-B12), (2 ×
2.8 µ
g/day), or equivalent doses of endogenous B12 (mainly hydroxo-B12 (HO-B12)) in whey pow
2.8 µ
g/day), or equivalent doses of endogenous B12 (mainly hydroxo-B12 (HO-B12)) in whey pow
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::315ff996f241665b86fe4223683dce36
https://pure.au.dk/ws/files/168156552/nutrients_11_02382.pdf
https://pure.au.dk/ws/files/168156552/nutrients_11_02382.pdf
Publikováno v:
Fedosov, S N, Nexo, E & Heegaard, C W 2019, ' Vitamin B 12 and its binding proteins in milk from cow and buffalo in relation to bioavailability of B 12 ', Journal of Dairy Science, vol. 102, no. 6, pp. 4891-4905 . https://doi.org/10.3168/jds.2018-15016
Milk is an important source of highly bioavailable vitamin B 12 (cobalamin) in human nutrition. In most animal products, vitamin B 12 is strongly bound to various specific protein carriers. The 2 vitamin B 12 -specific proteins, predominantly transco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71e1fab8215a2406ac9e0723a4089436
https://pure.au.dk/portal/da/publications/vitamin-b-12-and-its-binding-proteins-in-milk-from-cow-and-buffalo-in-relation-to-bioavailability-of-b-12(d552f50e-a507-4f05-a1b8-a8e3b89a25fc).html
https://pure.au.dk/portal/da/publications/vitamin-b-12-and-its-binding-proteins-in-milk-from-cow-and-buffalo-in-relation-to-bioavailability-of-b-12(d552f50e-a507-4f05-a1b8-a8e3b89a25fc).html