Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Sergey N, Zolov"'
Autor:
Ilias Christodoulou, Ruyan Rahnama, Jonas W. Ravich, Jaesung Seo, Sergey N. Zolov, Andrew N. Marple, David M. Markovitz, Challice L. Bonifant
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
H84T-Banana Lectin (BanLec) CAR-NK cells bind high mannose glycosites that decorate the SARS-CoV-2 envelope, thereby decreasing cellular infection in a model of SARS-CoV-2. H84T-BanLec CAR-NK cells are innate effector cells, activated by virus. This
Externí odkaz:
https://doaj.org/article/e1a08cabdeee4585bd26b7c7a028c51f
Supplementary Figures 1-7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::243102eb04ccc0a60df879c94334ed80
https://doi.org/10.1158/2326-6066.22542417.v1
https://doi.org/10.1158/2326-6066.22542417.v1
The development of engineered T cells to treat acute myeloid leukemia (AML) is challenging due to difficulty in target selection and the need for robust T-cell expansion and persistence. We designed a T cell stimulated to kill AML cells based on reco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::012afef17b86fc3f14e42e2303286b03
https://doi.org/10.1158/2326-6066.c.6549915
https://doi.org/10.1158/2326-6066.c.6549915
Publikováno v:
Cancer Immunol Res
The development of engineered T cells to treat acute myeloid leukemia (AML) is challenging due to difficulty in target selection and the need for robust T-cell expansion and persistence. We designed a T cell stimulated to kill AML cells based on reco
Autor:
Hyo Je Cho, Tomasz Cierpicki, Sidney Weaver, Dymytrii Listunov, Sergey N. Zolov, Jolanta Grembecka, Venkateshwar G. Keshamouni, Alyssa Winkler, Miranda L. Simes, Alexandrea N. Rizo, EunGi Kim, Brian M. Linhares
Publikováno v:
Cell Chem Biol
GAS41 is an emerging oncogene overexpressed and implicated in multiple cancers, including non-small cell lung cancer (NSCLC). GAS41 is a dimeric protein that contains the YEATS domain, which is involved in the recognition of lysine-acylated histones.
Autor:
Mathieu, Cinato, Laurie, Guitou, Amira, Saidi, Andrei, Timotin, Erwan, Sperazza, Thibaut, Duparc, Sergey N, Zolov, Sai Srinivas Panapakkam, Giridharan, Lois S, Weisman, Laurent O, Martinez, Jerome, Roncalli, Oksana, Kunduzova, Helene, Tronchere, Frederic, Boal
Publikováno v:
Theranostics
Rationale: TGFβ signaling pathway controls tissue fibrotic remodeling, a hallmark in many diseases leading to organ injury and failure. In this study, we address the role of Apilimod, a pharmacological inhibitor of the lipid kinase PIKfyve, in the r
Publikováno v:
Cytotherapy. 20:1259-1266
Targeted adoptive immunotherapy with engineered T cells is a promising treatment for refractory hematologic malignancies. However, many patients achieving early complete remissions ultimately relapse. Immunosuppressive ligands are expressed on tumor
Autor:
David M. Markovitz, Jaesung Seo, Wesley J. Ravich, Ruyan Rahnama, Ilias Christodoulou, Andrew Marple, Sergey N. Zolov, Challice L. Bonifant
Publikováno v:
Blood
Introduction: Banana Lectin (BanLec) is a glycoprotein-binding lectin derived from banana fruit that has antiviral activity. BanLec binds high mannose glycans expressed on the viral envelopes of HIV, Ebola, influenza, and coronaviruses. BanLec mitoge
Autor:
Guy M Lenk, Cole J Ferguson, Clement Y Chow, Natsuko Jin, Julie M Jones, Adrienne E Grant, Sergey N Zolov, Jesse J Winters, Roman J Giger, James J Dowling, Lois S Weisman, Miriam H Meisler
Publikováno v:
PLoS Genetics, Vol 7, Iss 6, p e1002104 (2011)
CMT4J is a severe form of Charcot-Marie-Tooth neuropathy caused by mutation of the phosphoinositide phosphatase FIG4/SAC3. Affected individuals are compound heterozygotes carrying the missense allele FIG4-I41T in combination with a null allele. Analy
Externí odkaz:
https://doaj.org/article/cd74d35fb1ce4500920a713d4c05f2f2
Autor:
Patrice Fort, Thomas W. Gardner, Ravi S.J. Singh, Hisanori Imai, Sergey N. Zolov, Mandy K. Losiewicz
Publikováno v:
The Journal of Biological Chemistry
The retinal insulin receptor (IR) exhibits basal kinase activity equivalent to that of the liver of fed animals, but unlike the liver, does not fluctuate with feeding and fasting; it also declines rapidly after the onset of insulin-deficient diabetes