Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Sergey M. Dzekunov"'
Autor:
Amar Bir Singh Sidhu, Bronwen Naudé, Kirk W. Deitsch, Angela K. Talley, Takashi Nomura, Roland A. Cooper, Sergey M. Dzekunov, Lyann M. B. Ursos, David A. Fidock, John C. Wootton, Paul D. Roepe, Thomas E. Wellems, Xin-zhuan Su, Michael T. Ferdig
Publikováno v:
Molecular Cell. 6:861-871
The determinant of verapamil-reversible chloroquine resistance (CQR) in a Plasmodium falciparum genetic cross maps to a 36 kb segment of chromosome 7. This segment harbors a 13-exon gene, pfcrt, having point mutations that associate completely with C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0068647106f873f7c31a86e5da9af8ed
https://doi.org/10.1016/s1097-2765(05)00077-8
https://doi.org/10.1016/s1097-2765(05)00077-8
Publikováno v:
Molecular and Biochemical Parasitology. 110:107-124
We present the first single cell-level analysis of digestive vacuolar pH for representative chloroquine resistant (strain Dd2) versus sensitive (strain HB3) malarial parasites. Human red blood cells harboring intact intraerythrocytic parasites were a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6be03b256ac5d0804328b9ceaa269238
https://doi.org/10.1016/s0166-6851(00)00261-9
https://doi.org/10.1016/s0166-6851(00)00261-9
Publikováno v:
Molecular and Biochemical Parasitology. 119:307-309
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40da1aafe553de91e830e74f2852c5ce
https://doi.org/10.1016/s0166-6851(01)00406-6
https://doi.org/10.1016/s0166-6851(01)00406-6
Publikováno v:
Novartis Foundation Symposium 226-Transport and Trafficking in the Malaria-Infected Erythrocyte
The biochemical mechanism of chloroquine resistance in Plasmodium falciparum remains unknown. We postulated that chloroquine-resistant strains could alter ion fluxes that then indirectly control drug accumulation within the parasite by affecting pH a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40e70ce8d14ae900c88a15521a0fc253
https://doi.org/10.1002/9780470515730.ch18
https://doi.org/10.1002/9780470515730.ch18
Autor:
Paul D. Roepe, Sergey M. Dzekunov, Tyler N. Bennett, Amar Bir Singh Sidhu, Lyann M. B. Ursos, David A. Fidock, Andrew D. Kosar
Publikováno v:
Molecular and biochemical parasitology. 133(1)
Elucidating the altered physiology of various chloroquine resistant (CQR) strains of Plasmodium falciparum is essential for understanding the molecular basis of CQR. In this study, we have devised several new methods for analyzing digestive vacuolar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95453708e3a5a868b49c2277db222136
https://pubmed.ncbi.nlm.nih.gov/14668017
https://pubmed.ncbi.nlm.nih.gov/14668017
Publikováno v:
Molecular and biochemical parasitology. 110(1)
In the preceding paper, we present a novel method for measuring the digestive vacuolar pH (pH(vac)) of the malarial parasite Plasmodium falciparum, and show that, surprisingly, pH(vac) is lower for chloroquine resistant (CQR) Dd2 parasites relative t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2666c18038e01d16206e342b88477566
https://pubmed.ncbi.nlm.nih.gov/10989150
https://pubmed.ncbi.nlm.nih.gov/10989150
Publikováno v:
The Journal of biological chemistry. 274(16)
In previous work (Weisburg, J. H., Curcio, M., Caron, P. C., Raghi, G., Mechetner, E. B., Roepe, P. D., and Scheinberg, D. A. (1996) J. Exp. Med. 183, 2699–2704), we showed that multidrug resistance (MDR) cells created by continuous selection with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1297dc49c14348d295e93a132e7bb5ad
https://pubmed.ncbi.nlm.nih.gov/10196165
https://pubmed.ncbi.nlm.nih.gov/10196165
Autor:
Vladimir Sidorov, Stefan Matile, Paul D. Roepe, Sergey M. Dzekunov, Bereket Ghebremariam, David Abdallah
Publikováno v:
Chemical Communications, Vol. 34, No 15 (1999) pp. 1429-1430
The diverse supramolecular chemistry of a rigid, T-shaped single-chain amphiphile, including giant vesicles, spherical and tubular reversed micelles, and gels, is described in comparison to that of rigid-rod amphiphiles of different length.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57e56be0d45d9740753a5a6924aac0c8
https://doi.org/10.1039/a903041g
https://doi.org/10.1039/a903041g
Autor:
Sergey M. Dzekunov, Ephrem Tekle, P B Chock, Hammou Oubrahim, Juergen F. Kolb, Karl H. Schoenbach
Publikováno v:
ResearcherID
Electric pulses across intact vesicles and cells can lead to transient increase in permeability of their membranes. We studied the integrity of these membranes in response to external electric pulses of high amplitude and submicrosecond duration with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdbd0823c057576ea3cd1009bb31c8a4
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000226378502039&KeyUID=WOS:000226378502039
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000226378502039&KeyUID=WOS:000226378502039