Zobrazeno 1 - 10
of 261
pro vyhledávání: '"Sergey M. Deyev"'
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Rapid uptake of nanoparticles by mononuclear phagocyte system (MPS) significantly hampers their therapeutic efficacy. Temporal MPS blockade is one of the few ways to overcome this barrier – the approach rediscovered many times under differ
Externí odkaz:
https://doaj.org/article/3f67625ef1a74d36aae18281e0409161
Autor:
Iaroslav B. Belyaev, Ivan V. Zelepukin, Polina A. Kotelnikova, Gleb V. Tikhonowski, Anton A. Popov, Alina Yu. Kapitannikova, Jugal Barman, Alexey N. Kopylov, Daniil N. Bratashov, Ekaterina S. Prikhozhdenko, Andrei V. Kabashin, Sergey M. Deyev, Andrei V. Zvyagin
Publikováno v:
Advanced Science, Vol 11, Iss 20, Pp n/a-n/a (2024)
Abstract Biodegradable nanomaterials can significantly improve the safety profile of nanomedicine. Germanium nanoparticles (Ge NPs) with a safe biodegradation pathway are developed as efficient photothermal converters for biomedical applications. Ge
Externí odkaz:
https://doaj.org/article/6a0ff56e02394d0896870d0ddd6f88d8
Autor:
Roman Zelchan, Vladimir Chernov, Anna Medvedeva, Anastasia Rybina, Olga Bragina, Elizaveta Mishina, Mariia Larkina, Ruslan Varvashenya, Anastasia Fominykh, Alexey Schulga, Elena Konovalova, Anzhelika Vorobyeva, Anna Orlova, Liubov Tashireva, Sergey M. Deyev, Vladimir Tolmachev
Publikováno v:
Cancers, Vol 16, Iss 16, p 2815 (2024)
A high level of EpCAM overexpression in lung cancer makes this protein a promising target for targeted therapy. Radionuclide visualization of EpCAM expression would facilitate the selection of patients potentially benefiting from such treatment. Sing
Externí odkaz:
https://doaj.org/article/d71372dc039b4c5ebb03647402773917
Autor:
Anton L. Popov, Danil D. Kolmanovich, Nikita N. Chukavin, Ivan V. Zelepukin, Gleb V. Tikhonowski, Andrei I. Pastukhov, Anton A. Popov, Alexander E. Shemyakov, Sergey M. Klimentov, Vladimir A. Ryabov, Sergey M. Deyev, Irina N. Zavestovskaya, Andrei V. Kabashin
Publikováno v:
Molecules, Vol 29, Iss 16, p 3936 (2024)
Boron-enhanced proton therapy has recently appeared as a promising approach to increase the efficiency of proton therapy on tumor cells, and this modality can further be improved by the use of boron nanoparticles (B NPs) as local sensitizers to achie
Externí odkaz:
https://doaj.org/article/6731ee67d3094ad59f337a15fd4a6972
Autor:
Daniel V. Kalinovsky, Irina V. Kholodenko, Elena V. Svirshchevskaya, Alexey V. Kibardin, Dmitry Yu. Ryazantsev, Fedor N. Rozov, Sergey S. Larin, Sergey M. Deyev, Roman V. Kholodenko
Publikováno v:
Current Issues in Molecular Biology, Vol 45, Iss 10, Pp 8112-8125 (2023)
Oligomerization of antibody fragments via modification with polyethylene glycol (pegylation) may alter their function and properties, leading to a multivalent interaction of the resulting constructs with the target antigen. In a recent study, we gene
Externí odkaz:
https://doaj.org/article/bf8e0d4d6862409b924c8a06a327194f
Autor:
Irina A. Ishina, Inna N. Kurbatskaia, Azad E. Mamedov, Elena I. Shramova, Sergey M. Deyev, Kamila S. Nurbaeva, Yury P. Rubtsov, Alexey A. Belogurov, Alexander G. Gabibov, Maria Y. Zakharova
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 11 (2024)
The identification of low-frequency antigen-specific CD4+ T cells is crucial for effective immunomonitoring across various diseases. However, this task still encounters experimental challenges necessitating the implementation of enrichment procedures
Externí odkaz:
https://doaj.org/article/a129dec8781a47c7902bb97ebee31679
Autor:
Sergey M. Deyev, Maryam Oroujeni, Javad Garousi, Torbjörn Gräslund, Ruonan Li, Alia Hani Binti Rosly, Anna Orlova, Elena Konovalova, Alexey Schulga, Anzhelika Vorobyeva, Vladimir Tolmachev
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 8, p 4246 (2024)
Designed ankyrin repeat protein (DARPin) G3 is an engineered scaffold protein. This small (14.5 kDa) targeting protein binds with high affinity to human epidermal growth factor receptor 2 (HER2). HER2 is overexpressed in several cancers. The use of t
Externí odkaz:
https://doaj.org/article/12a7cc2e5d4d4661b07a0431cf300507
Autor:
Ludmila G. Alekseeva, Olga V. Ovsyanikova, Alexey A. Schulga, Maria V. Grechikhina, Olga A. Shustova, Elena I. Kovalenko, Elena V. Svirshchevskaya, Sergey M. Deyev, Alexander M. Sapozhnikov
Publikováno v:
Cells, Vol 13, Iss 4, p 317 (2024)
(1) Background: We have previously shown that the use of an artificial supramolecular two-component system based on chimeric recombinant proteins 4D5scFv-barnase and barstar-heat shock protein 70 KDa (HSP70) allows targeted delivery of HSP70 to the s
Externí odkaz:
https://doaj.org/article/2b5af5d8233f457481386f74029cfef6
Autor:
Alexey V. Yaremenko, Ivan V. Zelepukin, Ilya N. Ivanov, Roman O. Melikov, Nadezhda A. Pechnikova, Dzhuliia Sh. Dzhalilova, Aziz B. Mirkasymov, Vera A. Bragina, Maxim P. Nikitin, Sergey M. Deyev, Petr I. Nikitin
Publikováno v:
Journal of Nanobiotechnology, Vol 20, Iss 1, Pp 1-15 (2022)
Abstract Magnetic nanoparticles are widely used in biomedicine for MRI imaging and anemia treatment. The aging of these nanomaterials in vivo may lead to gradual diminishing of their contrast properties and inducing toxicity. Here, we describe observ
Externí odkaz:
https://doaj.org/article/d2f5badbca99409bb7b024fd23bd9c3e
Autor:
Ivan V. Zelepukin, Olga Yu. Griaznova, Konstantin G. Shevchenko, Andrey V. Ivanov, Ekaterina V. Baidyuk, Natalia B. Serejnikova, Artur B. Volovetskiy, Sergey M. Deyev, Andrei V. Zvyagin
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Achieving the delivery of drugs into the centre of solid tumours is a challenge due to the tumour micro-environment. Here, the authors propose a system for using the rapid release of large quantities of drug inside tumour microcapillaries for the gra
Externí odkaz:
https://doaj.org/article/800d3698795f429d9d8762e7d9c772dd