Výsledky vyhledávání - "Sergey Ketlinsky"

Recombinant human interleukin-1 beta: new possibilities for the prophylaxis and correction of toxic myelodepression in patients with malignant tumors. I. Phase I-II clinical trials of recombinant human interleukin-1 beta as a leukopoiesis stimulator in cancer patients receiving combination chemotherapy

Autor: Ml, Gershanovich, Lv, Filatova, Sergey Ketlinsky, As, Simbirtsev

Publikováno v: Europe PubMed Central

Human recombinant interleukin-1 beta (IL-1beta), administered by intravenous drop infusion, at doses of 10-20 ng/kg daily over 5 days, to a group of 67 patients suffering from malignant tumors and with grade II-IV toxic leukopenia, caused an increase

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::cca014d1c3b9b0c995960c6eece1bae5
https://pubmed.ncbi.nlm.nih.gov/11781194

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Mechanisms of local immunostimulating action of interleukin-1β. Interleukin-1β stimulation of functional activity of human neutrophilic granulocytes in the inflammation focus

Autor: Varyushina, E. A., Konusova, V. G., Simbirtsev, A. S., Sergey Ketlinsky, Salamatov, A. V., Zolotarev, D. V., Bisenkov, L. N.

Publikováno v: Scopus-Elsevier

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::1384c77df999d317775cdec811597c37
http://www.scopus.com/inward/record.url?eid=2-s2.0-0033882980&partnerID=MN8TOARS

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Participation of tumor necrosis factor-α in immunoregulation of chronic progressive forms of multiple sclerosis

Autor: Demina, T. L., Boiko, A. N., Oganezov, V. K., Sergey Ketlinsky, Prokopyev, A. A., Balashov, K. E., Pinegin, B. V.

Publikováno v: Scopus-Elsevier

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::40caf6e2c7d4464058ebef0a703256db
http://www.scopus.com/inward/record.url?eid=2-s2.0-0025916306&partnerID=MN8TOARS

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Intact and impaired neutrophils in vivo: Functional effects of recombinant interleukin 1β

Autor: Nesterova, I. V., Kolesnikova, N. V., Chudilova, G. A., Danilova, I. I., Sergey Ketlinsky, Simbirtsev, A. S.

Publikováno v: Scopus-Elsevier

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::574e5ee3c3b1163e6cbf52856ba48cfe
http://www.scopus.com/inward/record.url?eid=2-s2.0-0027443826&partnerID=MN8TOARS

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Purification and characterization of the immunostimulatory properties of recombinant human interleukin-1 beta

Autor: Sergey Ketlinsky, Simbirtsev, A., Poltorack, A., Protasov, E., Solovjeva, L., Putchkova, G., Konusova, V., Pigareva, N., Kalinina, N., Perumov, N. D.

Publikováno v: Europe PubMed Central
Scopus-Elsevier

In this study we have used a new method for human recombinant IL-1 beta (rIL-1 beta) purification and investigated its immunostimulatory biological activity. The IL-1 beta gene was cloned using a novel mRNA preparation from activated human blood mono

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::3de3c4a843092c12fc846dba71304dd0
http://europepmc.org/abstract/med/1873490

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Recombinant human interleukin-1 beta: new possibilities for the prophylaxis and correction of toxic myelodepression in patients with malignant tumors. II. Phase II study of the protective effect of recombinant human interleukin-1 beta on myelodepression induced by chemotherapy in cancer patients

Autor: Ml, Gershanovich, Lv, Filatova, Sergey Ketlinsky, As, Simbirtsev

Publikováno v: Europe PubMed Central

The clinical study of human recombinant IL-1beta as a leukopoiesis protector, administered intravenously and subcutaneously, simultaneously with the chemotherapy, confirmed the "protective" effect of this cytokine in patients with grade II leukopenia

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::722501bc0fa7aaaf7a23889dd073d608
http://europepmc.org/abstract/med/11781195

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