Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Sergey G. Morozov"'
Autor:
Sergey A. Menzikov, Danila M. Zaichenko, Aleksey A. Moskovtsev, Sergey G. Morozov, Aslan A. Kubatiev
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
γ-Aminobutyric acid type A receptors (GABAARs) are members of the pentameric ligand-gated ion channel (pLGIC) family, which are widespread throughout the invertebrate and vertebrate central nervous system. GABAARs are engaged in short-term changes o
Externí odkaz:
https://doaj.org/article/5d96546cf7854bf0a324020fdab33eb0
Autor:
Agamurad A. Orazmuradov, Sergey G. Morozov, Anastasiya N. Akhmatova, Khalid Haddad, Alexander M. Lopatin, Fatima U. Ramazanova, Irina V. Bekbaeva, Sergey I. Kyrtikov, Zhasmina Z. Suleymanova, Aleksey A. Lukaev
Publikováno v:
International Journal of Biomedicine, Vol 11, Iss 4, Pp 418-421 (2021)
Background: This study aimed at finding the diagnostic and prognostic possibilities of determining apoC-II, as a serological marker for MM in early gestation. Methods and Results: The study included 182 pregnant women aged between 18 and 45 years a
Externí odkaz:
https://doaj.org/article/0c2917c8e47841bcadc83bcc520063fe
Autor:
Evgenii G. Skurikhin, Olga Pershina, Natalia Ermakova, Angelina Pakhomova, Darius Widera, Mariia Zhukova, Edgar Pan, Lubov Sandrikina, Lena Kogai, Nikolai Kushlinskii, Sergey G. Morozov, Aslan Kubatiev, Alexander Dygai
Publikováno v:
Biomedicines, Vol 10, Iss 6, p 1450 (2022)
CD8+ T-lymphocytes play a key role in antitumor immune response. Patients with lung cancer often suffer from T-lymphocyte dysfunction and low T-cell counts. The exhaustion of effector T-lymphocytes largely limits the effectiveness of therapy. In this
Externí odkaz:
https://doaj.org/article/1793dad86e2f4025a71011239a194a65
Autor:
Irina M. Zurina, Anastasiya A. Gorkun, Ekaterina V. Dzhussoeva, Tamara D. Kolokoltsova, Dmitriy D. Markov, Nastasia V. Kosheleva, Sergey G. Morozov, Irina N. Saburina
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
Pigmentation is the result of melanin synthesis, which takes place in melanocytes, and its further distribution. A dysregulation in melanocytes' functionality can result in the loss of pigmentation, the appearance of pigment spots and melanoma develo
Externí odkaz:
https://doaj.org/article/2da6c15f722e4b6791aa50f5a14525a3
Autor:
Olga Pershina, Natalia Ermakova, Angelina Pakhomova, Darius Widera, Edgar Pan, Mariia Zhukova, Elena Slonimskaya, Sergey G. Morozov, Aslan Kubatiev, Alexander Dygai, Evgenii G. Skurikhin
Publikováno v:
Biomedicines, Vol 9, Iss 9, p 1223 (2021)
New drug targets, markers of disease prognosis, and more efficient treatment options are an unmet clinical need in breast cancer (BC). We have conducted a pilot study including patients with luminal B stage breast cancer IIA–IIIB. The presence and
Externí odkaz:
https://doaj.org/article/edebd5e7ec9f4232a9ab81044b26cce3
Autor:
Eleonora A. Braga, Marina V. Fridman, Vitaly I. Loginov, Alexey A. Dmitriev, Sergey G. Morozov
Publikováno v:
Frontiers in Genetics, Vol 10 (2019)
Clear cell renal cell carcinoma (ccRCC) is the third most common urological cancer, and it has the highest mortality rate. The increasing drug resistance of metastatic ccRCC has resulted in the search for new biomarkers. Epigenetic regulatory mechani
Externí odkaz:
https://doaj.org/article/bd227e8c5e054107980efb8b95f41850
Autor:
Fatima M. Shakova, Yuliya I. Kirova, Denis N. Silachev, Galina A. Romanova, Sergey G. Morozov
Publikováno v:
Brain Sciences, Vol 11, Iss 3, p 325 (2021)
The pharmacological induction and activation of peroxisome proliferator-activated receptor gamma coactivator 1 alpha (PGC-1α), a key regulator of ischemic brain tolerance, is a promising direction in neuroprotective therapy. Pharmacological agents w
Externí odkaz:
https://doaj.org/article/34ee7b82fca043e0acdbd937550eab21
Autor:
Arthur T. Kopylov, Anna L. Kaysheva, Olga Papysheva, Iveta Gribova, Galina Kotaysch, Lubov Kharitonova, Tatiana Mayatskaya, Anna Krasheninnikova, Sergey G. Morozov
Publikováno v:
Cells, Vol 9, Iss 4, p 1032 (2020)
Background: The purpose of the study is to establish and quantitatively assess protein markers and their combination in association with insulin uptake that may be have value for early prospective recognition of diabetic fetopathy (DF) as a complicat
Externí odkaz:
https://doaj.org/article/96486cc88604461a900bf7c3a2a74adb
Autor:
Sergey A. Menzikov, Danila M. Zaichenko, Aleksey A. Moskovtsev, Sergey G. Morozov, Aslan A. Kubatiev
Publikováno v:
International Journal of Molecular Sciences
Volume 24
Issue 3
Pages: 2764
Volume 24
Issue 3
Pages: 2764
Zinc ions (Zn2+) are concentrated in various brain regions and can act as a neuromodulator, targeting a wide spectrum of postsynaptic receptors and enzymes. Zn2+ inhibits the GABAARs, and its potency is profoundly affected by the subunit composition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b9d68b770f8d8bfed98525eb5db86a2
Autor:
Evgenii G. Skurikhin, Olga Pershina, Natalia Ermakova, Angelina Pakhomova, Mariia Zhukova, Edgar Pan, Lubov Sandrikina, Darius Widera, Lena Kogai, Nikolai Kushlinskii, Aslan Kubatiev, Sergey G. Morozov, Alexander Dygai
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 24; Pages: 15780
Using a model of Lewis lung carcinoma (LLC) in vitro and in vivo, we previously demonstrated increased antitumor activity in CD8+ T-cells reprogrammed with an MEK inhibitor and PD-1 blocker. In this follow-up study, we carried out the reprogramming o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d41fa5fd3a6a237e92a21e19a928957