Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Sergey Chuvpilo"'
Publikováno v:
Pharmaceutics, Vol 16, Iss 8, p 986 (2024)
MicroRNAs (miRNAs) are short non-coding RNAs that regulate gene expression by inhibiting the translation of target transcripts. The expression profiles of miRNAs vary in different tissues and change with the development of diseases, including cancer.
Externí odkaz:
https://doaj.org/article/5a34b0cd38c74b678ff46c25c774a72f
Autor:
Dmitry Tyrsin, Thomas Hünig, Sergey Chuvpilo, Thomas Bukur, John C. Castle, Ulrich Kalinke, Hartmut Hengel, Valesca Boisguerin, Paula Tabares, Alexey A. Matskevich, Linda Y. Semmler, Patrick Bartholomaeus, Paula S. Römer
Publikováno v:
The Journal of Immunology. 192:2091-2098
Following inconspicuous preclinical testing, the superagonistic anti-CD28 mAb TGN1412 was applied to six study participants who all developed a devastating cytokine storm. We verified that TGN1412 treatment of fresh PBMCs induced only moderate respon
Autor:
Dmitry, Tyrsin, Sergey, Chuvpilo, Alexey, Matskevich, Daniil, Nemenov, Paula S, Römer, Paula, Tabares, Thomas, Hünig
Publikováno v:
Clinical and experimental rheumatology. 34(4 Suppl 98)
CD28 superagonists (CD28SA) are CD28-specific monoclonal antibodies which are able to activate T-cells without overt TCR engagement. In rodents, CD28SA efficiently activate regulatory T-cells and are therapeutically effective in multiple models of au