Zobrazeno 1 - 10
of 239
pro vyhledávání: '"Sergey A. Samsonov"'
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 19, Iss 1, Pp 1933-1946 (2023)
In the past few decades, glycosaminoglycan (GAG) research has been crucial for gaining insights into various physiological, pathological, and therapeutic aspects mediated by the direct interactions between the GAG molecules and diverse proteins. The
Externí odkaz:
https://doaj.org/article/8c743831d28c400ead18196a59a6672e
Publikováno v:
European Journal of Medicinal Chemistry Reports, Vol 9, Iss , Pp 100118- (2023)
There is a constant necessity of finding new, reliable antimicrobials, due to the rapid emergence of antibiotic resistant bacteria. This paper tries to address this issue, as the possibility of formation of Pd(II) and Pt(II) coordination compounds of
Externí odkaz:
https://doaj.org/article/17954c3b5a104bac96b2fffa65b216e6
Autor:
Brianda L. Santini, Margrethe Gaardløs, Dariusz Wyrzykowski, Sven Rothemund, Anja Penk, Martin Zacharias, Sergey A. Samsonov
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 23, Iss , Pp 2985-2994 (2024)
Cyclic peptides present a robust platform for drug design, offering high specificity and stability due to their conformationally constrained structures. In this study, we introduce an updated version of the Cyclic Peptide Matching program (cPEPmatch)
Externí odkaz:
https://doaj.org/article/35f5e31773204f40aabdbcb950c9b903
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 2188-2196 (2023)
The mannuronan C-5 epimerases catalyze epimerization of β-d-mannuronic acid to α-l-guluronic acid in alginate polymers. The seven extracellular Azotobacter vinelandii epimerases (AvAlgE1–7) are calcium-dependent, and calcium is essential for the
Externí odkaz:
https://doaj.org/article/1e81e762910647c5848f623c763ec7d4
Autor:
Marta Pągielska, Sergey A. Samsonov
Publikováno v:
Biomolecules, Vol 13, Iss 2, p 247 (2023)
Glycosaminoglycans (GAGs) are a class of linear anionic periodic polysaccharides containing disaccharide repetitive units. These molecules interact with a variety of proteins in the extracellular matrix and so participate in biochemically crucial pro
Externí odkaz:
https://doaj.org/article/47dd1dc449e04beca64b545e1bd2a135
The potential role of glycosaminoglycans in serum amyloid A fibril formation by in silico approaches
Publikováno v:
Matrix Biology Plus, Vol 12, Iss , Pp 100080- (2021)
Serum amyloid A (SAA) is actively involved in such pathological processes as atherosclerosis, rheumatoid arthritis, cancer and Alzheimer's disease by its aggregation. One of the factors that can attenuate its aggregation and so affects its physiologi
Externí odkaz:
https://doaj.org/article/ada064b4b9ed4ee1a218314ab4eaa51d
Publikováno v:
Molecules, Vol 27, Iss 9, p 2654 (2022)
Glycosaminoglycans (GAGs) are a class of periodic anionic linear polysaccharides involved in a number of biologically relevant processes in the extracellular matrix via interactions with various types of molecules including proteins, peptides and sma
Externí odkaz:
https://doaj.org/article/ea1e323b11ff49139715c18f7921a0c4
Autor:
Eirini-Maria Giatagana, Aikaterini Berdiaki, Margrethe Gaardløs, Sergey A. Samsonov, George N. Tzanakakis, Dragana Nikitovic
Publikováno v:
Cancers, Vol 14, Iss 5, p 1196 (2022)
Osteosarcoma (OS) is a mesenchymally derived, aggressive bone cancer. OS cells produce an aberrant nonmineralized or partly mineralized extracellular matrix (ECM) whose components participate in signaling pathways connected to specific pathogenic phe
Externí odkaz:
https://doaj.org/article/c73627cb5b704b24bc8dba3c4bfd6a38
Autor:
Ola Grabowska, Małgorzata M. Kogut, Krzysztof Żamojć, Sergey A. Samsonov, Joanna Makowska, Aleksandra Tesmar, Katarzyna Chmur, Dariusz Wyrzykowski, Lech Chmurzyński
Publikováno v:
Molecules, Vol 26, Iss 21, p 6565 (2021)
The binding interactions of bovine serum albumin (BSA) with tetraphenylborate ions ([B(Ph)4]−) have been investigated by a set of experimental methods (isothermal titration calorimetry, steady-state fluorescence spectroscopy, differential scanning
Externí odkaz:
https://doaj.org/article/f8050874dd1e496c8b2ce31d97167efa
Autor:
Adam Liwo, Cezary Czaplewski, Adam K. Sieradzan, Agnieszka G. Lipska, Sergey A. Samsonov, Rajesh K. Murarka
Publikováno v:
Biomolecules, Vol 11, Iss 9, p 1347 (2021)
Molecular dynamics with coarse-grained models is nowadays extensively used to simulate biomolecular systems at large time and size scales, compared to those accessible to all-atom molecular dynamics. In this review article, we describe the physical b
Externí odkaz:
https://doaj.org/article/e7ff07350cd848e6afbc2b062b474009