Zobrazeno 1 - 10
of 147
pro vyhledávání: '"Sergey A. Akimov"'
Autor:
Amy Rice, Sourav Haldar, Eric Wang, Paul S. Blank, Sergey A. Akimov, Timur R. Galimzyanov, Richard W. Pastor, Joshua Zimmerberg
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Target membrane poration is a longstanding enigma in virology. Here, authors show that fusion peptides of the influenza virus’ spike protein aggregate, rotate, and tilt in membranes, facilitating peptide-induced poration during viral fusion.
Externí odkaz:
https://doaj.org/article/032e71bde5444d9ea7d8158275f55efe
Autor:
Oleg V. Kondrashov, Sergey A. Akimov
Publikováno v:
Biomolecules, Vol 13, Iss 12, p 1731 (2023)
Thickness of lipid bilayer membranes is a key physical parameter determining membrane permeability and stability with respect to formation of through pores. Most membrane inclusions or impurities like amphipathic peptides, transmembrane peptides, lip
Externí odkaz:
https://doaj.org/article/25872299332448508e01376975055b55
Publikováno v:
Membranes, Vol 13, Iss 10, p 816 (2023)
The lipid membranes of living cells are composed of a large number of lipid types and can undergo phase separation with the formation of nanometer-scale liquid-ordered lipid domains, also called rafts. Raft coalescence, i.e., the fusion of lipid doma
Externí odkaz:
https://doaj.org/article/ac559f2ea7704b15ae95d39bf7ca5191
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
The lipid matrix of cellular membranes, directly and indirectly, regulates many vital functions of the cell. The diversity of lipids in membranes leads to the formation of ordered domains called rafts, which play a crucial role in signal transduction
Externí odkaz:
https://doaj.org/article/92c00a87c1fa497e810aa4bb5b734e31
Publikováno v:
Biomolecules, Vol 13, Iss 2, p 352 (2023)
Proton relay between interfacial water molecules allows rapid two-dimensional diffusion. An energy barrier, ΔGr‡, opposes proton-surface-to-bulk release. The ΔGr‡-regulating mechanism thus far has remained unknown. Here, we explored the effect
Externí odkaz:
https://doaj.org/article/e97aa4ac8f4644e3b270fdb2b9014cd5
Autor:
Svyatoslav S. Sokolov, Marina M. Popova, Peter Pohl, Andreas Horner, Sergey A. Akimov, Natalia A. Kireeva, Dmitry A. Knorre, Oleg V. Batishchev, Fedor F. Severin
Publikováno v:
Membranes, Vol 12, Iss 12, p 1278 (2022)
Yeast S. cerevisiae has been shown to suppress a sterol biosynthesis as a response to hyperosmotic stress. In the case of sodium stress, the failure to suppress biosynthesis leads to an increase in cytosolic sodium. The major yeast sterol, ergosterol
Externí odkaz:
https://doaj.org/article/0c78cdd056db4d9fae5e6bc35eea38ec
Autor:
Oleg V. Kondrashov, Sergey A. Akimov
Publikováno v:
Membranes, Vol 13, Iss 1, p 25 (2022)
Genome replication of coronaviruses takes place in specific cellular compartments, in so-called double-membrane vesicles (DMVs), formed from the endoplasmic reticulum (ER). An intensive production of DMVs is induced by non-structural viral proteins.
Externí odkaz:
https://doaj.org/article/638a9f319cc448d2bf24cad35ea43741
Autor:
Pavel E. Volynsky, Alexandra I. Smirnova, Sergey A. Akimov, Svyatoslav S. Sokolov, Fedor F. Severin
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Externí odkaz:
https://doaj.org/article/2635849c7d644574af2a0f5d034b4f40
Publikováno v:
Frontiers in Medical Technology, Vol 3 (2021)
Externí odkaz:
https://doaj.org/article/dfbc6b56c2cf41c588824337605a1adb
Autor:
Ali Saitov, Maksim A. Kalutsky, Timur R. Galimzyanov, Toma Glasnov, Andreas Horner, Sergey A. Akimov, Peter Pohl
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 7, p 3502 (2022)
Lipid domains less than 200 nm in size may form a scaffold, enabling the concerted function of plasma membrane proteins. The size-regulating mechanism is under debate. We tested the hypotheses that large values of spontaneous monolayer curvature are
Externí odkaz:
https://doaj.org/article/df101aa663e3442fb083fee5dc19c5ad