Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Sergey, Kurdyukov"'
Autor:
Sina Jami, Jennifer R. Deuis, Tabea Klasfauseweh, Xiaoyang Cheng, Sergey Kurdyukov, Felicity Chung, Andrei L. Okorokov, Shengnan Li, Jiangtao Zhang, Ben Cristofori-Armstrong, Mathilde R. Israel, Robert J. Ju, Samuel D. Robinson, Peng Zhao, Lotten Ragnarsson, Åsa Andersson, Poanna Tran, Vanessa Schendel, Kirsten L. McMahon, Hue N. T. Tran, Yanni K.-Y. Chin, Yifei Zhu, Junyu Liu, Theo Crawford, Saipriyaa Purushothamvasan, Abdella M. Habib, David A. Andersson, Lachlan D. Rash, John N. Wood, Jing Zhao, Samantha J. Stehbens, Mehdi Mobli, Andreas Leffler, Daohua Jiang, James J. Cox, Stephen G. Waxman, Sulayman D. Dib-Hajj, G. Gregory Neely, Thomas Durek, Irina Vetter
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Voltage-gated sodium (NaV) channels are critical regulators of neuronal excitability and are targeted by many toxins that directly interact with the pore-forming α subunit, typically via extracellular loops of the voltage-sensing domains, o
Externí odkaz:
https://doaj.org/article/ef7fee6301d340c5b67edc494cc4b801
Autor:
Olga Rafikova, Joel James, Cody A. Eccles, Sergey Kurdyukov, Maki Niihori, Mathews Valuparampil Varghese, Ruslan Rafikov
Publikováno v:
Biology of Sex Differences, Vol 11, Iss 1, Pp 1-9 (2020)
Abstract Background The mechanisms involved in pulmonary hypertension (PH) development in patients and pre-clinical models are poorly understood. PH has a well-established sex dimorphism in patients with increased frequency of PH in females, and more
Externí odkaz:
https://doaj.org/article/291f43c415554f9aabf17c80db58e337
Publikováno v:
PLoS ONE, Vol 15, Iss 4, p e0231267 (2020)
Women are known to be associated with a higher susceptibility to pulmonary arterial hypertension (PAH). In contrast, male PAH patients have a worse survival prognosis. In this study, we investigated whether the contribution of sex goes beyond the eff
Externí odkaz:
https://doaj.org/article/a1934eded2bd4ebebe50ce170190b8b9
Autor:
Mathews Valuparampil Varghese, Maki Niihori, Cody A Eccles, Sergey Kurdyukov, Joel James, Olga Rafikova, Ruslan Rafikov
Publikováno v:
Antioxidants, Vol 9, Iss 2, p 104 (2020)
Pulmonary arterial hypertension (PAH) is a chronic cardiopulmonary disorder instigated by pulmonary vascular cell proliferation. Activation of Akt was previously reported to promote vascular remodeling. Also, the irreversible nitration of Y350 residu
Externí odkaz:
https://doaj.org/article/d702ca3aac01466b8f9a01bbcbc6ae70
Autor:
Sergey Kurdyukov, Cody A Eccles, Ankit A Desai, Manuel Gonzalez-Garay, Jason X-J Yuan, Joe G N Garcia, Olga Rafikova, Ruslan Rafikov
Publikováno v:
PLoS ONE, Vol 13, Iss 8, p e0203493 (2018)
Pulmonary Arterial Hypertension (PAH) is a fatal disorder with limited treatment options and reduced life expectancy after diagnosis. Complex genetic backgrounds in PAH complicates identification of causative mutations that is essential for an unders
Externí odkaz:
https://doaj.org/article/f5cecf18802948468813981919888e37
Autor:
Javier, Moral-Sanz, Manuel A, Fernandez-Rojo, Gonzalo, Colmenarejo, Sergey, Kurdyukov, Andreas, Brust, Lotten, Ragnarsson, Åsa, Andersson, Sabela F, Vila, Pablo, Cabezas-Sainz, Patrick, Wilhelm, Ana, Vela-Sebastián, Isabel, Fernández-Carrasco, Yanni K Y, Chin, Yaiza, López-Mancheño, Taylor B, Smallwood, Richard J, Clark, Bryan G, Fry, Glenn F, King, Grant A, Ramm, Paul F, Alewood, Richard J, Lewis, Jason P, Mulvenna, Glen M, Boyle, Laura E, Sanchez, G Gregory, Neely, John J, Miles, Maria P, Ikonomopoulou
Publikováno v:
British journal of pharmacologyREFERENCES. 179(20)
Over past decades, targeted therapies and immunotherapy have improved survival and reduced the morbidity of patients with BRAF-mutated melanoma. However, drug resistance and relapse hinder overall success. Therefore, there is an urgent need for novel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7ef35fafb47aa03b3a57c1b164f86a95
https://pubmed.ncbi.nlm.nih.gov/35818835
https://pubmed.ncbi.nlm.nih.gov/35818835
Autor:
Anna A. Stepanova, Alexander Galkin, Maki Niihori, Sergey Kurdyukov, Mathews Valuparampil Varghese, Olga Rafikova, Marina A. Zemskova, Cody A. Eccles, Ruslan Rafikov
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 62:231-242
NFU1 is a mitochondrial protein that is involved in the biosynthesis of iron-sulfur clusters, and its genetic modification is associated with disorders of mitochondrial energy metabolism. Patients ...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d87f6adb0b5a6106db31296e5c552ca5
https://doi.org/10.1165/rcmb.2019-0065oc
https://doi.org/10.1165/rcmb.2019-0065oc
Autor:
Deanne Francis, Xiaowen Duan, Akiyoshi Hirayama, Yushi Kamei, Sergey Kurdyukov, Lake-Ee Quek, Sarah D. Elkington, Satsuki Ikeda, David E. James, James R. Krycer, Alexis Díaz-Vegas, Fiona Weiss, Tomoyoshi Soga, Uttam K. Tambar, Kristen C. Cooke, Daniel J. Fazakerley, Ping Xin Zhou, Gregory J. Cooney
Publikováno v:
J Biol Chem
Adipose tissue is essential for whole-body glucose homeostasis, with a primary role in lipid storage. It has been previously observed that lactate production is also an important metabolic feature of adipocytes, but its relationship to adipose and wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c22078b8b49463b856bbeabe844a5e1
https://doi.org/10.1074/jbc.ra119.011178
https://doi.org/10.1074/jbc.ra119.011178
Publikováno v:
Lecture Notes in Networks and Systems ISBN: 9783030936761
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dbd3f0eb1624dda79957ef8810b33d3c
https://doi.org/10.1007/978-3-030-93677-8_40
https://doi.org/10.1007/978-3-030-93677-8_40
Autor:
Helena Åberg, Sergey Kurdyukov, Roderick J. Clifton-Bligh, Grace Lim, Martyn Bullock, Ying Zhu
Publikováno v:
Thyroid. 29:1623-1633
Background: Co-occurrence of TERT (telomerase reverse transcriptase) promoter (TERTp) mutations with BRAF/RAS mutations is associated with significantly more aggressive thyroid cancer. TERTp mutati...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2cdd300dafee26af94641cc97ef7daa
https://doi.org/10.1089/thy.2018.0314
https://doi.org/10.1089/thy.2018.0314