Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Sergei Yu. Noskov"'
Autor:
Hristina R. Zhekova, Jiansen Jiang, Weiguang Wang, Kirill Tsirulnikov, Gülru Kayık, Hanif Muhammad Khan, Rustam Azimov, Natalia Abuladze, Liyo Kao, Debbie Newman, Sergei Yu. Noskov, D. Peter Tieleman, Z. Hong Zhou, Alexander Pushkin, Ira Kurtz
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-13 (2022)
CryoEM structures and computational modeling of bovine anion exchanger 1 in both inward and outward facing conformations reveal an elevator-like mechanism of ion transport by a solute carrier ion transport family 4 member.
Externí odkaz:
https://doaj.org/article/a87cecb4c5cf4b3eb5b6a1ab6c4bead0
Autor:
Weiguang Wang, Kirill Tsirulnikov, Hristina R. Zhekova, Gülru Kayık, Hanif Muhammad Khan, Rustam Azimov, Natalia Abuladze, Liyo Kao, Debbie Newman, Sergei Yu. Noskov, Z. Hong Zhou, Alexander Pushkin, Ira Kurtz
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
The mechanisms involved in SLC4-mediated ion transport are still under debate. Here, the authors present a cryoEM structure of the Sodium-driven Chloride/Bicarbonate Exchanger NDCBE, which - together with computational modeling and mutagenesis - reve
Externí odkaz:
https://doaj.org/article/5450105e6774470bbdbd14557832e365
Autor:
Williams E. Miranda, Jiqing Guo, Haydee Mesa-Galloso, Valentina Corradi, James P. Lees-Miller, D. Peter Tieleman, Henry J. Duff, Sergei Yu. Noskov
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
The lipid regulation of mammalian ion channel function has emerged as a fundamental mechanism in the control of electrical signalling and transport specificity. Here, the authors combine molecular dynamics simulations, mutagenesis, and electrophysiol
Externí odkaz:
https://doaj.org/article/f5eb9a98c2804d9bb7a7f7b17805b054
Autor:
David Kerk, Mario E. Valdés-Tresanco, Ryan Toth, Sergei Yu. Noskov, Kenneth K.-S. Ng, Greg B. Moorhead
Publikováno v:
BBA Advances, Vol 1, Iss , Pp 100005- (2021)
Background: Phosphoprotein phosphatases (PPP) belong to the PPP Sequence family, which in turn belongs to the broader metallophosphoesterase (MPE) superfamily. The relationship between the PPP Sequence family and other members of the MPE superfamily
Externí odkaz:
https://doaj.org/article/de6d77dcf5ea48508a1691d8b862e2d7
Autor:
Meruyert Kudaibergenova, Jiqing Guo, Hanif M. Khan, Farhan Zahid, James Lees-Miller, Sergei Yu. Noskov, Henry J. Duff
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Human-ether-a-go-go-related channel (hERG1) is the pore-forming domain of the delayed rectifier K+ channel in the heart which underlies the IKr current. The channel has been extensively studied due to its propensity to bind chemically diverse group o
Externí odkaz:
https://doaj.org/article/879c8e1fbdac4643966727b7d6174254
Autor:
Weiguang Wang, Kirill Tsirulnikov, Hristina R. Zhekova, Gülru Kayık, Hanif Muhammad Khan, Rustam Azimov, Natalia Abuladze, Liyo Kao, Debbie Newman, Sergei Yu. Noskov, Z. Hong Zhou, Alexander Pushkin, Ira Kurtz
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-1 (2021)
Externí odkaz:
https://doaj.org/article/74de58f1135e43a3aa7c8c4d7832cd69
Autor:
Dennis R. Salahub, Sergei Yu. Noskov, Bogdan Lev, Rui Zhang, Van Ngo, Annick Goursot, Patrizia Calaminici, Andreas M. Köster, Aurelio Alvarez-Ibarra, Daniel Mejía-Rodríguez, Jan Řezáč, Fabien Cailliez, Aurélien de la Lande
Publikováno v:
Molecules, Vol 20, Iss 3, Pp 4780-4812 (2015)
The density functional code deMon2k employs a fitted density throughout (Auxiliary Density Functional Theory), which offers a great speed advantage without sacrificing necessary accuracy. Powerful Quantum Mechanical/Molecular Mechanical (QM/MM) appro
Externí odkaz:
https://doaj.org/article/1d53c5b6ce0d467f975353ca8918df0b
Autor:
Irene Hiniesto-Iñigo, Laura M. Castro-Gonzalez, Valentina Corradi, Mark A. Skarsfeldt, Samira Yazdi, Siri Lundholm, Johan Nikesjö, Sergei Yu Noskov, Bo Hjorth Bentzen, D. Peter Tieleman, Sara I. Liin
Publikováno v:
EBioMedicine, Vol 89, Iss , Pp 104459- (2023)
Summary: Background: Genotype-positive patients who suffer from the cardiac channelopathy Long QT Syndrome (LQTS) may display a spectrum of clinical phenotypes, with often unknown causes. Therefore, there is a need to identify factors influencing dis
Externí odkaz:
https://doaj.org/article/68cc94b6c4f549b4b603e7aeba51442e
Autor:
Meruyert Kudaibergenova, Jiqing Guo, Hanif M. Khan, James Lees-Miller, Mahdi Mousaei, Williams Miranda, Van A. Ngo, Sergei Yu Noskov, D. Peter Tieleman, Henry J. Duff
Publikováno v:
Biophysical Journal. 121:4585-4599
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::895d852b87ba1d2943131dcfe5ebfb59
https://doi.org/10.1016/j.bpj.2022.10.032
https://doi.org/10.1016/j.bpj.2022.10.032
Autor:
Van A. Ngo, María Queralt-Martín, Farha Khan, Lucie Bergdoll, Jeff Abramson, Sergey M. Bezrukov, Tatiana K. Rostovtseva, David P. Hoogerheide, Sergei Yu. Noskov
Publikováno v:
Journal of the American Chemical Society
Journal of the American Chemical Society, 2022, 144 (32), pp.14564-14577. ⟨10.1021/jacs.2c03316⟩
Journal of the American Chemical Society, 2022, 144 (32), pp.14564-14577. ⟨10.1021/jacs.2c03316⟩
International audience; The voltage-dependent anion channel (VDAC) is a βbarrel channel of the mitochondrial outer membrane (MOM) that passively transports ions, metabolites, polypeptides, and single-stranded DNA. VDAC responds to a transmembrane po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbc2f632f05d8a57d137102d99aa2323
https://pubmed.ncbi.nlm.nih.gov/35925797
https://pubmed.ncbi.nlm.nih.gov/35925797