Zobrazeno 1 - 10
of 137
pro vyhledávání: '"Sergei Y, Sokol"'
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Vertebrate neural tube closure is associated with complex changes in cell shape and behavior, however, the relative contribution of these processes to tissue folding is not well understood. At the onset of Xenopus neural tube folding, we obs
Externí odkaz:
https://doaj.org/article/6fc60d84da6e4269a7cba619ed54ca27
Autor:
Alice H. Reis, Sergei Y. Sokol
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract The Wnt pathway activates target genes by controlling the β-catenin-T-cell factor (TCF) transcriptional complex during embryonic development and cancer. This pathway can be potentiated by R-spondins, a family of proteins that bind RNF43/ZNR
Externí odkaz:
https://doaj.org/article/68c876ec32c943778a5e1a6e65d5ca45
Publikováno v:
Biology Open, Vol 10, Iss 7 (2021)
Coordinated polarization of cells in the tissue plane, known as planar cell polarity (PCP), is associated with a signaling pathway critical for the control of morphogenetic processes. Although the segregation of PCP components to opposite cell border
Externí odkaz:
https://doaj.org/article/e629c025255d4576ab7000fcbf4aacbb
Publikováno v:
iScience, Vol 24, Iss 6, Pp 102520- (2021)
Summary: Dorsoventral patterning of a vertebrate embryo critically depends on the activity of Smad1 that mediates signaling by BMP proteins, anti-dorsalizing morphogenetic protein (Admp), and their antagonists. Pinhead (Pnhd), a cystine-knot-containi
Externí odkaz:
https://doaj.org/article/51abbeae3e434743a93bfe97dab43705
Publikováno v:
PLoS ONE, Vol 16, Iss 10 (2021)
Wilms tumor-1-interacting protein (Wtip) is a LIM-domain-containing adaptor that links cell junctions with actomyosin complexes and modulates actomyosin contractility and ciliogenesis in Xenopus embryos. The Wtip C-terminus with three LIM domains ass
Externí odkaz:
https://doaj.org/article/11d51c5900e149f2b05e96db0bc08b93
Publikováno v:
PLoS ONE, Vol 14, Iss 5, p e0216083 (2019)
The use of Xenopus laevis as a model for vertebrate developmental biology is limited by a lack of antibodies specific for embryonic antigens. This study evaluated the use of immune and non-immune phage display libraries for the isolation of single do
Externí odkaz:
https://doaj.org/article/07473f47543c4fd19b2c99767c96ade1
Publikováno v:
eLife, Vol 7 (2018)
Vertebrate neural tube formation depends on the coordinated orientation of cells in the tissue known as planar cell polarity (PCP). In the Xenopus neural plate, PCP is marked by the enrichment of the conserved proteins Prickle3 and Vangl2 at anterior
Externí odkaz:
https://doaj.org/article/88da7f4d3fa845538c6a87cd5d66859b
Publikováno v:
Biology Open, Vol 4, Iss 6, Pp 722-730 (2015)
The vertebrate neural tube forms as a result of complex morphogenetic movements, which require the functions of several core planar cell polarity (PCP) proteins, including Vangl2 and Prickle. Despite the importance of these proteins for neurulation,
Externí odkaz:
https://doaj.org/article/061475d9b94c4d67ae2c9f7bbcedb850
Autor:
Sergei Y. Sokol, Elena Torban
Publikováno v:
Nat Rev Nephrol
Planar cell polarity (PCP) refers to the coordinated orientation of cells in tissue plane. Originally discovered and studied in Drosophila melanogaster, PCP is now widely recognized in vertebrates, where it has been implicated in organogenesis. Speci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb42441bf63ceec4364345ee6c8a1186
https://doi.org/10.1038/s41581-021-00395-6
https://doi.org/10.1038/s41581-021-00395-6
Autor:
Chih-Wen Chu, Sergei Y Sokol
Publikováno v:
eLife, Vol 5 (2016)
The coordinated orientation of cells across the tissue plane, known as planar cell polarity (PCP), is manifested by the segregation of core PCP proteins to different sides of the cell. Secreted Wnt ligands are involved in many PCP-dependent processes
Externí odkaz:
https://doaj.org/article/483785a40fa448489710a5b8ea2868d0