Zobrazeno 1 - 10
of 128
pro vyhledávání: '"Sergei V Strelkov"'
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0126248 (2015)
Physico-chemical properties of the mutations G34R, P39L and E41K in the N-terminal domain of human heat shock protein B1 (HspB1), which have been associated with hereditary motor neuron neuropathy, were analyzed. Heat-induced aggregation of all mutan
Externí odkaz:
https://doaj.org/article/3d82948e80174eb6ae7880217a6320cf
Dissecting the functional role of the N-terminal domain of the human small heat shock protein HSPB6.
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e105892 (2014)
HSPB6 is a member of the human small heat shock protein (sHSP) family, a conserved group of molecular chaperones that bind partially unfolded proteins and prevent them from aggregating. In vertebrate sHSPs the poorly structured N-terminal domain has
Externí odkaz:
https://doaj.org/article/a2257862d32e4b0e9f79b8b1920cccb9
Autor:
Pieter-Jan Vermeire, Anastasia V. Lilina, Hani M. Hashim, Lada Dlabolová, Jan Fiala, Steven Beelen, Zdeněk Kukačka, Jeremy N. Harvey, Petr Novák, Sergei V. Strelkov
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/133c3e35d17b4d598dd6ede16ac5ccd5
Autor:
Giovanni Monaco, Elke Decrock, Koen Nuyts, Larry E Wagner, Tomas Luyten, Sergei V Strelkov, Ludwig Missiaen, Wim M De Borggraeve, Luc Leybaert, David I Yule, Humbert De Smedt, Jan B Parys, Geert Bultynck
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e73386 (2013)
The anti-apoptotic Bcl-2 protein is the founding member and namesake of the Bcl-2-protein family. It has recently been demonstrated that Bcl-2, apart from its anti-apoptotic role at mitochondrial membranes, can also directly interact with the inosito
Externí odkaz:
https://doaj.org/article/747ce4b098844d3589df01d73cd04aeb
Autor:
Natalia Smiejkowska, Lauren Oorts, Kevin Van Calster, Linda De Vooght, Rob Geens, Henri-Philippe Mattelaer, Koen Augustyns, Sergei V. Strelkov, Dirk Lamprecht, Koen Temmerman, Yann G.-J. Sterckx, Davie Cappoen, Paul Cos
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 3 (2024)
ABSTRACTThe World Health Organization’s goal to combat tuberculosis (TB) is hindered by the emergence of anti-microbial resistance, therefore necessitating the exploration of new drug targets. Multidrug regimens are indispensable in TB therapy as t
Externí odkaz:
https://doaj.org/article/c8fac40f6384460fafe887ecb260e268
Autor:
Pieter-Jan Vermeire, Anastasia V. Lilina, Hani M. Hashim, Lada Dlabolová, Jan Fiala, Steven Beelen, Zdeněk Kukačka, Jeremy N. Harvey, Petr Novák, Sergei V. Strelkov
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract Intermediate filaments (IFs) are essential constituents of the metazoan cytoskeleton. A vast family of cytoplasmic IF proteins are capable of self-assembly from soluble tetrameric species into typical 10–12 nm wide filaments. The primary s
Externí odkaz:
https://doaj.org/article/4815cc6da527458d859f7d1766b80d15
Autor:
Pieter-Jan Vermeire, Giel Stalmans, Anastasia V. Lilina, Jan Fiala, Petr Novak, Harald Herrmann, Sergei V. Strelkov
Publikováno v:
Cells, Vol 10, Iss 9, p 2457 (2021)
Given the role of intermediate filaments (IFs) in normal cell physiology and scores of IF-linked diseases, the importance of understanding their molecular structure is beyond doubt. Research into the IF structure was initiated more than 30 years ago,
Externí odkaz:
https://doaj.org/article/dc1a8cb3a8764bbea674d41b6a05b95e
Autor:
Baole Zhang, Luping Pang, Manesh Nautiyal, Steff De Graef, Bharat Gadakh, Eveline Lescrinier, Jef Rozenski, Sergei V. Strelkov, Stephen D. Weeks, Arthur Van Aerschot
Publikováno v:
Molecules, Vol 25, Iss 20, p 4751 (2020)
Aminoacyl-tRNA synthetases (aaRSs) have become viable targets for the development of antimicrobial agents due to their crucial role in protein translation. A series of six amino acids were coupled to the purine-like 7-amino-5-hydroxymethylbenzimidazo
Externí odkaz:
https://doaj.org/article/1539736222b44698a5e71c211dda45c2
Autor:
Anastasia V. Lilina, Simon Leekens, Hani M. Hashim, Pieter‐Jan Vermeire, Jeremy N. Harvey, Sergei V. Strelkov
Publikováno v:
Protein science : a publication of the Protein Society. 31(12)
Intermediate filaments (IFs) form an essential part of the metazoan cytoskeleton. Despite a long history of research, a proper understanding of their molecular architecture and assembly process is still lacking. IFs self-assemble from elongated dimer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08e5aa91194659f60d878eb8e1bc4155
https://pubmed.ncbi.nlm.nih.gov/36369679
https://pubmed.ncbi.nlm.nih.gov/36369679
Autor:
Evgenii M. Osipov, Ali H. Munawar, Steven Beelen, Daren Fearon, Alice Douangamath, Conor Wild, Stephen D. Weeks, Arthur Van Aerschot, Frank von Delft, Sergei V. Strelkov
Publikováno v:
RSC Chemical Biology
Polyomaviruses are a family of ubiquitous double-stranded DNA viruses many of which are human pathogens. These include BK polyomavirus which causes severe urinary tract infection in immunocompromised patients and Merkel cell polyomavirus associated w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71b1fce72e036baea4be23472be6e453
https://lirias.kuleuven.be/handle/20.500.12942/694475
https://lirias.kuleuven.be/handle/20.500.12942/694475
