Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Sergei V Chetyrkin"'
Autor:
Aaron L Fidler, Carl E Darris, Sergei V Chetyrkin, Vadim K Pedchenko, Sergei P Boudko, Kyle L Brown, W Gray Jerome, Julie K Hudson, Antonis Rokas, Billy G Hudson
Publikováno v:
eLife, Vol 6 (2017)
The role of the cellular microenvironment in enabling metazoan tissue genesis remains obscure. Ctenophora has recently emerged as one of the earliest-branching extant animal phyla, providing a unique opportunity to explore the evolutionary role of th
Externí odkaz:
https://doaj.org/article/e19f2cf7fd724dce8e52fab510ae0f42
Autor:
Billy G. Hudson, Ryan Bauer, Jarrod A. Smith, Sergey Ivanov, Paul A. Voziyan, Sergei P. Boudko, Sergei V. Chetyrkin
Publikováno v:
The Journal of Biological Chemistry
Our recent work identified a genetic variant of the α345 hexamer of the collagen IV scaffold that is present in patients with glomerular basement membrane diseases, Goodpasture's disease (GP) and Alport syndrome (AS), and phenocopies of AS in knock-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6f16cd9d5f41724d2208df598a6a4ce
https://doi.org/10.1016/j.jbc.2021.100591
https://doi.org/10.1016/j.jbc.2021.100591
Autor:
George Haddad, Charles D. Pusey, Agnes B. Fogo, Dale R. Abrahamson, Rudolf P. Wüthrich, Clifford E. Kashtan, Alicia Simmons, Paul A. Voziyan, Fernando C. Fervenza, Sergei P. Boudko, Timo Wagner, Zhao Wei Cui, A. Richard Kitching, Raymond C. Harris, Eric Delpire, Andreas D. Kistler, Johan M. Lorenzen, Ming-Hui Zhao, Aaron L. Fidler, Sergei V. Chetyrkin, Ariana Gaspert, Carsten Bergmann, Oliver Gross, Billy G. Hudson, Maik Grohmann, Marten Segelmark, Harald Seeger, Elena Pokidysheva, Stephen P. McAdoo, Vadim Pedchenko
Publikováno v:
The Journal of Biological Chemistry
Diseases of the glomerular basement membrane (GBM), such as Goodpasture’s disease (GP) and Alport syndrome (AS), are a major cause of chronic kidney failure and an unmet medical need. Collagen IVα345 is an important architectural element of the GB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ed717b2a810710cfdf2e9dee7466f10
https://doi.org/10.1016/j.jbc.2021.100590
https://doi.org/10.1016/j.jbc.2021.100590
Autor:
Paul A. Voziyan, Carl Darris, Billy G. Hudson, Otto A. Sanchez, Hartman Madu, Josh Avance, Kristie L. Rose, Sergei V. Chetyrkin
Publikováno v:
Free Radical Biology and Medicine. 89:83-90
Diabetes is characterized, in part, by activation of toxic oxidative and glycoxidative pathways that are triggered by persistent hyperglycemia and contribute to diabetic complications. Inhibition of these pathways may benefit diabetic patients by del
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69438859d60e42e0dd0f22d8e8a66ded
https://doi.org/10.1016/j.freeradbiomed.2015.07.001
https://doi.org/10.1016/j.freeradbiomed.2015.07.001
Autor:
Sergei V. Chetyrkin, Carl Darris, W. Gray Jerome, Billy G. Hudson, Aaron L. Fidler, Vadim Pedchenko, Antonis Rokas, Julie K. Hudson, Kyle L. Brown, Sergei P. Boudko
Publikováno v:
eLife
eLife, Vol 6 (2017)
eLife, Vol 6 (2017)
The role of the cellular microenvironment in enabling metazoan tissue genesis remains obscure. Ctenophora has recently emerged as one of the earliest-branching extant animal phyla, providing a unique opportunity to explore the evolutionary role of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c55b89088f8d44a3d65bac1ea5a601d3
https://doi.org/10.7554/elife.24176
https://doi.org/10.7554/elife.24176
Autor:
Billy G. Hudson, Sergei P. Boudko, W. Gray Jerome, Julie K. Hudson, Carl Darris, Aaron L. Fidler, Vadim Pedchenko, Sergei V. Chetyrkin, Antonis Rokas, Kyle L. Brown
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::55dc3ed92727805d4bbe8376e3ebbfe8
https://doi.org/10.7554/elife.24176.029
https://doi.org/10.7554/elife.24176.029
Autor:
Corina M. Borza, Yan Su, Roy Zent, Stacey Mont, Paul A. Voziyan, Hyunil Jo, Ambra Pozzi, Sergei V. Chetyrkin, Paul C. Billings, Xiwu Chen, Billy G. Hudson, Joel S. Bennett, Beate Eckes, Ling Yu, William F. DeGrado
Publikováno v:
Journal of the American Society of Nephrology. 23:1027-1038
Mesangial cells and podocytes express integrins α1β1 and α2β1, which are the two major collagen receptors that regulate multiple cellular functions, including extracellular matrix homeostasis. Integrin α1β1 protects from glomerular injury by ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6209cb9beb0c444e689b85db7494430
https://doi.org/10.1681/asn.2011040367
https://doi.org/10.1681/asn.2011040367
Autor:
Paul A. Voziyan, Xavier Shackelford, Sergei V. Chetyrkin, Missy Mathis, Billy G. Hudson, W. Hayes McDonald
Publikováno v:
Biochemical and Biophysical Research Communications. 411:574-579
Oxidative damage to proteins is one of the major pathogenic mechanisms in many chronic diseases. Therefore, inhibition of this oxidative damage can be an important part of therapeutic strategies. Pyridoxamine (PM), a prospective drug for treatment of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f51239af6f7507577acd05d6650ddb15
https://doi.org/10.1016/j.bbrc.2011.06.188
https://doi.org/10.1016/j.bbrc.2011.06.188
Autor:
Anne-Claude Gingras, Jonathan B. Olsen, Sergei V. Chetyrkin, Guoqing Zhong, Denitza Roudeva, Anthony B. Mak, Ruth Isserlin, Jason Moffat, Cuihong Wan, Edyta Marcon, Sandra Smiley, Ginny I. Chen, Andrew Emili, Kim Blakely, Jack Greenblatt, Zuyao Ni, Joyce Li, Thanuja Punna, Johannes A. Hewel, Konstantina Karamboulas
Publikováno v:
Molecular & Cellular Proteomics. 9:811-823
Protein complexes and protein-protein interactions are essential for almost all cellular processes. Here, we establish a mammalian affinity purification and lentiviral expression (MAPLE) system for characterizing the subunit compositions of protein c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a2ece3f1d3832476628d70fade10237
https://doi.org/10.1074/mcp.m000002-mcp201
https://doi.org/10.1074/mcp.m000002-mcp201
Autor:
Paul A. Voziyan, Sergei V. Chetyrkin, Missy Mathis, Billy G. Hudson, Amy-Joan L. Ham, David L. Hachey
Publikováno v:
Free Radical Biology and Medicine. 44:1276-1285
Nonenzymatic modification of proteins is one of the key pathogenic factors in diabetic complications. Uncovering the mechanisms of protein damage caused by glucose is fundamental to understanding this pathogenesis and in the development of new therap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c71f8663275e0480d198b64346872810
https://doi.org/10.1016/j.freeradbiomed.2007.09.016
https://doi.org/10.1016/j.freeradbiomed.2007.09.016