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Autor:
Valentin Skryabin, Mikhail Zastrozhin, Alexandra Parkhomenko, Volker M. Lauschke, Valery Smirnov, Aleksey Petukhov, Elena Pankratenko, Sergei Pozdnyakov, Sergei Koporov, Natalia Denisenko, Kristina Akmalova, Evgeny Bryun, Dmitry Sychev
Publikováno v:
Current drug metabolism.
Background: Previous studies have shown that haloperidol biotransformation is mainly metabolized by CYP2D6. The CYP2D6 gene is highly polymorphic, contributing to inter-individual differences in enzymatic activity, and may impact haloperidol biotrans