Zobrazeno 1 - 10
of 128
pro vyhledávání: '"Sergei P, Atamas"'
Autor:
Anjana Singh, Adriaan O. Kraaijeveld, Adelina Curaj, Kanin Wichapong, Linda Hammerich, Saskia C. A. de Jager, Ilze Bot, Sergei P. Atamas, Theo J. C. van Berkel, J. Wouter Jukema, Iain Comerford, Shaun R. McColl, Barend Mees, Johan W. M. Heemskerk, Gerry A. F. Nicolaes, Tilman Hackeng, Elisa Anamaria Liehn, Frank Tacke, Erik A. L. Biessen
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionThe CC chemokine ligand 18 (CCL18) is a chemokine highly expressed in chronic inflammation in humans. Recent observations of elevated CCL18 plasma levels in patients with acute cardiovascular syndromes prompted an investigation into the r
Externí odkaz:
https://doaj.org/article/573017efcc53412a84624e171b71058e
Autor:
Eid A. Al-Mutairy, Somaya Al Qattan, Mohammed Khalid, Azizah A. Al-Enazi, Maher M. Al-Saif, Faiqa Imtiaz, Khushnooda Ramzan, Vineesh Raveendran, Ayodele Alaiya, Brian F. Meyer, Sergei P. Atamas, Kate S. Collison, Khalid S. Khabar, Jeffrey D. Hasday, Futwan Al-Mohanna
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Patients with digenic S100A3 and S100A13 mutations exhibited an atypical and progressive interstitial pulmonary fibrosis, with impaired intracellular calcium homeostasis and mitochondrial dysfunction. Here we provide direct evidence of a causative ef
Externí odkaz:
https://doaj.org/article/9beaf0213feb4ac5b53d12e80ef852b3
Autor:
Sang W. Hyun, Chiguang Feng, Anguo Liu, Erik P. Lillehoj, Rossana Trotta, Tami J. Kingsbury, Antonino Passaniti, Katerina N. Lugkey, Sitara Chauhan, John F. Cipollo, Irina G. Luzina, Sergei P. Atamas, Alan S. Cross, Simeon E. Goldblum
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-23 (2022)
Abstract To gain insight into sialic acid biology and sialidase/neuraminidase (NEU) expression in mature human neutrophil (PMN)s, we studied NEU activity and expression in PMNs and the HL60 promyelocytic leukemic cell line, and changes that might occ
Externí odkaz:
https://doaj.org/article/289ac30cc0a342a584ab79a26dfc59e5
Autor:
Ioana Ghita, Evangelia Piperi, Sergei P. Atamas, Soren M. Bentzen, Robert A. Ord, Donita Dyalram, Joshua E. Lubek, Rania H. Younis
Publikováno v:
Frontiers in Oral Health, Vol 3 (2022)
Head and neck squamous cell carcinoma (HNSCC) can be classified according to the histological inflammatory subtype (HIS) into inflamed (HIS-INF) or immune excluded (HIS-IE). HIS-IE was previously associated with higher levels of soluble Semaphorin 4D
Externí odkaz:
https://doaj.org/article/8c9fcc9a6d5740ba81df7e49bb48105d
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Mammalian neuraminidases (NEUs), also known as sialidases, are enzymes that cleave off the terminal neuraminic, or sialic, acid resides from the carbohydrate moieties of glycolipids and glycoproteins. A rapidly growing body of literature indicates th
Externí odkaz:
https://doaj.org/article/4c06ac6427314f3aa36a4f80dfa2fc3a
Autor:
Yizhan Guo, Zhongcheng Mei, Dongge Li, Anirban Banerjee, May A. Khalil, Allen Burke, Jon Ritter, Christine Lau, Daniel Kreisel, Andrew E. Gelman, Elizabeth Jacobsen, Irina G. Luzina, Sergei P. Atamas, Alexander Sasha Krupnick
Publikováno v:
American Journal of Transplantation. 22:1963-1975
Pathways regulating lung alloimmune responses differ from most other solid organs and remain poorly explored. Based on our recent work identifying the unique role of eosinophils in downregulating lung alloimmunity, we sought to define pathways contri
Autor:
Jean-Paul Courneya, Rita Fishelevich, Irina G. Luzina, Violeta Rus, Sergei P. Atamas, Brian Hampton, Alexander V. Misharin, Nevins W. Todd, Virginia Lockatell, Tudor C. Badea, Horea Rus
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 66:146-157
Some previous studies in tissue fibrosis have suggested a profibrotic contribution from elevated expression of a protein termed either Regulator of Cell Cycle (RGCC) or Response Gene to Complement 32 Protein (RGC-32). Our analysis of public gene expr
Autor:
Irina G. Luzina, Virginia Lockatell, Jean-Paul Courneya, Zhongcheng Mei, Rita Fishelevich, Pavel Kopach, Edward M. Pickering, Phillip H. Kang, Alexander S. Krupnick, Nevins W. Todd, Stefanie N. Vogel, Sergei P. Atamas
Publikováno v:
Cellular immunology. 383
Mature IL-33 (MIL33) acting through its receptor, ST2, is known to regulate fibrosis. The precursor, full-length IL-33 (FLIL33), may function differently from MIL33 and independently of ST2. Here we report that genetic deletion of either IL-33 or ST2
Autor:
Diana E. Amariei, Neal Dodia, Janaki Deepak, Stella E. Hines, Jeffrey R. Galvin, Sergei P. Atamas, Nevins W. Todd
Publikováno v:
Medicina, Vol 55, Iss 9, p 580 (2019)
Combined pulmonary fibrosis and emphysema (CPFE) has been increasingly recognized over the past 10−15 years as a clinical entity characterized by rather severe imaging and gas exchange abnormalities, but often only mild impairment in spirometric an
Externí odkaz:
https://doaj.org/article/0137874280bd4cf28b7c3a83e908e9e3
Autor:
Irina G. Luzina, Akihiro Imamura, Erik P. Lillehoj, Christopher W. Cairo, Simeon E. Goldblum, Sang W. Hyun, Katerina N. Lugkey, Virginia Lockatell, Hideharu Ishida, Sergei P. Atamas
Publikováno v:
J Pharmacol Exp Ther
Pulmonary fibrosis remains a serious biomedical problem with no cure and an urgent need for better therapies. Neuraminidases (NEUs), including NEU1, have been recently implicated in the mechanism of pulmonary fibrosis by us and others. We now have te