Zobrazeno 1 - 10
of 100
pro vyhledávání: '"Sergei N. Shchelkunov"'
Publikováno v:
Viruses, Vol 15, Iss 1, p 103 (2022)
Considering that vaccination against smallpox with live vaccinia virus led to serious adverse effects in some cases, the WHO, after declaration of the global eradication of smallpox in 1980, strongly recommended to discontinue the vaccination in all
Externí odkaz:
https://doaj.org/article/98f901eeaeda4a31a2b3c4c76af2eb86
Autor:
Sergei N. Shchelkunov, Stanislav N. Yakubitskiy, Alexander A. Sergeev, Ekaterina V. Starostina, Ksenia A. Titova, Stepan A. Pyankov, Galina A. Shchelkunova, Mariya B. Borgoyakova, Alexey M. Zadorozhny, Lyubov A. Orlova, Denis N. Kisakov, Larisa I. Karpenko
Publikováno v:
Viruses, Vol 14, Iss 7, p 1453 (2022)
The conventional live smallpox vaccine based on the vaccinia virus (VACV) cannot be widely used today because it is highly reactogenic. Therefore, there is a demand for designing VACV variants possessing enhanced immunogenicity, making it possible to
Externí odkaz:
https://doaj.org/article/7c9855202119445588ad2769503afd31
Autor:
Inga R. Grin, Grigory V. Mechetin, Rustem D. Kasymov, Evgeniia A. Diatlova, Anna V. Yudkina, Sergei N. Shchelkunov, Irina P. Gileva, Alexandra A. Denisova, Grigoriy A. Stepanov, Ghermes G. Chilov, Dmitry O. Zharkov
Publikováno v:
Molecules, Vol 26, Iss 21, p 6668 (2021)
Uracil–DNA glycosylases are enzymes that excise uracil bases appearing in DNA as a result of cytosine deamination or accidental dUMP incorporation from the dUTP pool. The activity of Family 1 uracil–DNA glycosylase (UNG) activity limits the effic
Externí odkaz:
https://doaj.org/article/4eccb9b2add64a62a6373d3ddfe88e90
Autor:
Sergei N. Shchelkunov, Alexander A. Sergeev, Stanislav N. Yakubitskiy, Ksenia A. Titova, Stepan A. Pyankov, Irina V. Kolosova, Ekaterina V. Starostina, Mariya B. Borgoyakova, Alexey M. Zadorozhny, Denis N. Kisakov, Irina S. Shulgina, Larisa I. Karpenko
Publikováno v:
Viruses, Vol 13, Iss 8, p 1631 (2021)
Mass vaccination has played a critical role in the global eradication of smallpox. Various vaccinia virus (VACV) strains, whose origin has not been clearly documented in most cases, have been used as live vaccines in different countries. These VACV s
Externí odkaz:
https://doaj.org/article/9724a2bc6d794a6287d7840378ce7ea5
Autor:
Sergei N. Shchelkunov, Stanislav N. Yakubitskiy, Kseniya A. Titova, Stepan A. Pyankov, Alexander A. Sergeev
Publikováno v:
Pathogens, Vol 10, Iss 3, p 377 (2021)
Following the WHO announcement of smallpox eradication, discontinuation of smallpox vaccination with vaccinia virus (VACV) was recommended. However, interest in VACV was soon renewed due to the opportunity of genetic engineering of the viral genome b
Externí odkaz:
https://doaj.org/article/730a3da100cd4226bfaea805f9110e4f
Autor:
Sergei N. Shchelkunov, Stanislav N. Yakubitskiy, Alexander A. Sergeev, Alexei S. Kabanov, Tatiana V. Bauer, Leonid E. Bulychev, Stepan A. Pyankov
Publikováno v:
Viruses, Vol 12, Iss 8, p 795 (2020)
The mass smallpox vaccination campaign has played a crucial role in smallpox eradication. Various strains of the vaccinia virus (VACV) were used as a live smallpox vaccine in different countries, their origin being unknown in most cases. The VACV str
Externí odkaz:
https://doaj.org/article/cd15bccc45574a50a2ab325a68c01759
Publikováno v:
Viruses, Vol 9, Iss 9, p 242 (2017)
Smallpox was the first human disease to be eradicated, through a concerted vaccination campaign led by the World Health Organization. Since its eradication, routine vaccination against smallpox has ceased, leaving the world population susceptible to
Externí odkaz:
https://doaj.org/article/1a1e30861da64072a6fd54cbc0ab36a1
Autor:
Sergei N. Shchelkunov
Publikováno v:
Advances in Virology, Vol 2012 (2012)
In the course of evolution, viruses have developed various molecular mechanisms to evade the defense reactions of the host organism. When understanding the mechanisms used by viruses to overcome manifold defense systems of the animal organism, repres
Externí odkaz:
https://doaj.org/article/e31054d75b5048db9b115cf3e89295e0
Autor:
Sergei N. Shchelkunov, Aleksander A. Sergeev, Ksenia A. Titova, Stepan A. Pyankov, Ekaterina V. Starostina, Maria B. Borgoyakova, Lubov A. Kisakova, Denis N. Kisakov, Larisa I. Karpenko, Stanislav N. Yakubitskiy
Publikováno v:
Acta Naturae. 14:111-118
The spread of the monkeypox virus infection among humans in many countries outside of Africa, which started in 2022, is now drawing the attention of the medical and scientific communities to the fact that immunization against this infection is sorely
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c4c2d7ecf0f4e98ee2819c35ff48794c
https://doi.org/10.32607/actanaturae.11857
https://doi.org/10.32607/actanaturae.11857
Autor:
Evgeniia A. Diatlova, Grigory V. Mechetin, Anna V. Yudkina, Vasily D. Zharkov, Natalia A. Torgasheva, Anton V. Endutkin, Olga V. Shulenina, Andrey L. Konevega, Irina P. Gileva, Sergei N. Shchelkunov, Dmitry O. Zharkov
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 11; Pages: 9113
The protein encoded by the vaccinia virus D4R gene has base excision repair uracil–DNA N-glycosylase (vvUNG) activity and also acts as a processivity factor in the viral replication complex. The use of a protein unlike PolN/PCNA sliding clamps is a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a739381e0dc3fa2f4b9ea2112cc20636
https://doi.org/10.3390/ijms24119113
https://doi.org/10.3390/ijms24119113