Zobrazeno 1 - 10
of 117
pro vyhledávání: '"Sergei M. Gryaznov"'
Autor:
Irina Ushach, Ren Zhu, Elen Rosler, Rajendra K. Pandey, N. Tilani S. De Costa, Soheil Pourshahian, Qinglin Han, Chris Li, Leonid Beigelman, Sergei M. Gryaznov, Theodore Yun
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 27, Iss , Pp 1103-1115 (2022)
Despite the existence of a prophylactic vaccine against hepatitis B virus (HBV), chronic hepatitis B virus (CHB) infection remains the leading cause of cirrhosis and liver cancer in developing countries. Because HBV persistence is associated with ins
Externí odkaz:
https://doaj.org/article/c5a1444410544bae827ef263c310aa7c
Autor:
Brittney-Shea Herbert, George W. Sledge, Sunil Badve, Kathy D. Miller, Sergei M. Gryaznov, Erin M. Goldblatt, Hongling Xiao, Amelia E. Hochreiter
Purpose: Maintenance of telomeres by telomerase is critical for the continuing proliferation of most advanced cancer cells. Telomerase activity has been detected in the vast majority of cancer cells but not most normal cells, making the enzyme an att
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2740a33f6e5763f786dbd1baad46ac5
https://doi.org/10.1158/1078-0432.c.6518346.v1
https://doi.org/10.1158/1078-0432.c.6518346.v1
Autor:
Brittney-Shea Herbert, George W. Sledge, Sunil Badve, Kathy D. Miller, Sergei M. Gryaznov, Erin M. Goldblatt, Hongling Xiao, Amelia E. Hochreiter
Supplementary Figure S1 from Telomerase Template Antagonist GRN163L Disrupts Telomere Maintenance, Tumor Growth, and Metastasis of Breast Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dd84e0a82940a8d3cd954b696898a4b
https://doi.org/10.1158/1078-0432.22441221.v1
https://doi.org/10.1158/1078-0432.22441221.v1
Autor:
Brittney-Shea Herbert, Changyu Shen, Sergei M. Gryaznov, Melanie J. Fox, Erin R. Gentry, Erin M. Goldblatt
Supplementary Table from The telomerase template antagonist GRN163L alters MDA-MB-231 breast cancer cell morphology, inhibits growth, and augments the effects of paclitaxel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f551f33044c4173f01eb1ac91d84d45
https://doi.org/10.1158/1535-7163.22485443
https://doi.org/10.1158/1535-7163.22485443
Autor:
Brittney-Shea Herbert, Changyu Shen, Sergei M. Gryaznov, Melanie J. Fox, Erin R. Gentry, Erin M. Goldblatt
Telomeres are repetitive (TTAGGG)n DNA sequences found at the end of chromosomes that protect the ends from recombination, end to end fusions, and recognition as damaged DNA. Telomerase activity can be detected in 85% to 90% of human tumors, which st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73d5cd03dc2972590d97d8d6c93294a6
https://doi.org/10.1158/1535-7163.c.6531941.v1
https://doi.org/10.1158/1535-7163.c.6531941.v1
Autor:
Brittney-Shea Herbert, George W. Sledge, Sunil Badve, Kathy D. Miller, Sergei M. Gryaznov, Erin M. Goldblatt, Hongling Xiao, Amelia E. Hochreiter
Supplementary Figure Legend from Telomerase Template Antagonist GRN163L Disrupts Telomere Maintenance, Tumor Growth, and Metastasis of Breast Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d90e08bb529ae2e185c6fe504fc9d54
https://doi.org/10.1158/1078-0432.22441224
https://doi.org/10.1158/1078-0432.22441224
Autor:
Brittney-Shea Herbert, Changyu Shen, Sergei M. Gryaznov, Melanie J. Fox, Erin R. Gentry, Erin M. Goldblatt
Supplementary Fig. from The telomerase template antagonist GRN163L alters MDA-MB-231 breast cancer cell morphology, inhibits growth, and augments the effects of paclitaxel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cc6b13f2682e510207f4c3d257fefcb
https://doi.org/10.1158/1535-7163.22485446.v1
https://doi.org/10.1158/1535-7163.22485446.v1
Publikováno v:
Current stem cell researchtherapy.
Abstract: Cancer stem cells (CSCs) are correlated with poor clinical outcome due to their contribution to chemotherapy resistance and formation of metastasis. Multiple cell surface and enzymatic markers have been characterized to identify CSCs, which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f87309ea3d1a70bcd6998d36050c9655
https://pubmed.ncbi.nlm.nih.gov/36263477
https://pubmed.ncbi.nlm.nih.gov/36263477
Autor:
Sergei M. Gryaznov, Soheil Pourshahian
Publikováno v:
Analytical Chemistry. 91:11154-11161
Hydrolysis of N3'-P5' phosphoramidate and thiophosphoramidate oligonucleotides with 0.1% formic acid leads to the cleavage of the 3' N-P bond and generates two products, one of which contains a 5'-phosphate. Analysis of the hydrolytic products by liq
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7d7f6efba2df7bc64240412fef542d8
https://doi.org/10.1021/acs.analchem.9b01858
https://doi.org/10.1021/acs.analchem.9b01858
Autor:
Sergei M. Gryaznov, Megan Johnstone, Pierfrancesco Tassone, Carl D. Novina, Nicola Amodio, Mehmet Kemal Samur, Woojun D Park, Leon Wert-Lamas, Anil Aktas-Samur, Masood A. Shammas, Doriana Gramegna, Massimo Loda, Jonathan E. Henninger, Kenneth C. Anderson, Nikhil C. Munshi, Richard A. Young, Caroline Ribeiro, Eugenio Morelli, Annamaria Gulla, Yu-Tzu Tai, Mariateresa Fulciniti
Publikováno v:
Blood. 138:894-894
To identify therapeutically actionable genetic dependencies we have pursued various approaches to derive a deeper understanding of the oncogenic hallmarks of myelomagenesis. We have studied the long noncoding RNA (lncRNA) landscape in multiple myelom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cafe54b8594092ba60ed5d145b5b1c01
https://doi.org/10.1182/blood-2021-151705
https://doi.org/10.1182/blood-2021-151705