Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Sergei L. Leonov"'
Autor:
Sergei L. Leonov
Publikováno v:
Bulletin of Baikal State University. 30:371-382
The trends in the volume and structure of revenues and expenditures of budgets of 11 Far Eastern regions for 2013–2019 are analyzed. An analysis of the balance of consolidated budgets and dynamics of the state regional debt based on statistical and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::91f2161c94fb69982975f8889a0840a0
https://doi.org/10.17150/2500-2759.2020.30(3).371-382
https://doi.org/10.17150/2500-2759.2020.30(3).371-382
Autor:
Sergei L. Leonov
Publikováno v:
Bulletin of Baikal State University. 29:314-323
The paper analyzes the features of the formation of «model» budgets, assesses the consequences of the transition to the distribution of subsidies to the subjects of the Russian Federation from the federal budget on the basis of the calculation of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d208e7de717834af28ecc9b47d9f13b4
https://doi.org/10.17150/2500-2759.2019.29(2).314-323
https://doi.org/10.17150/2500-2759.2019.29(2).314-323
Autor:
Ekaterina Vakulyuk, Sergei L. Leonov
Publikováno v:
Известия Байкальского государственного университета. 28:481-490
In different periods of modern history, the development of the state has always been based on certain models of interaction between the government and business, which were the most preferred ones at a particular historical moment. The article analyze
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::113117c2ae51f946f77cf74ea6d1d9e5
https://doi.org/10.17150/2500-2759.2018.28(3).481-490
https://doi.org/10.17150/2500-2759.2018.28(3).481-490
Publikováno v:
Pharmaceutical Statistics. 7:53-68
Multivariate techniques of O’Brien’s OLS and GLS statistics are discussed in the context of their application in clinical trials. We introduce the concept of an operational effect size and illustrate its use to evaluate power. An extension descri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::083ef26953f09393353156de07a05168
https://doi.org/10.1002/pst.268
https://doi.org/10.1002/pst.268
Autor:
Sergei L. Leonov, Robert C. Gagnon
Publikováno v:
Journal of Biopharmaceutical Statistics. 15:143-163
In various pharmaceutical applications, repeated measurements are taken from each subject, and model parameters are estimated from the collected data. Examples include dose response modeling and PK/PD studies with serial blood sampling, among others.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::472f30dc3389b486bc33a152af4837b2
https://doi.org/10.1081/bip-200040853
https://doi.org/10.1081/bip-200040853
Autor:
Valerii V. Fedorov, Sergei L. Leonov
Optimal Design for Nonlinear Response Models discusses the theory and applications of model-based experimental design with a strong emphasis on biopharmaceutical studies. The book draws on the authors'many years of experience in academia and the phar
Publikováno v:
Journal of Statistical Planning and Inference. 114:81-93
Principal components methods and factor analysis are popular tools for the dimension-reduction problem. These techniques can be used to obtain a smaller number of new variables. However, the new variables may include all or most of the original varia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d68abbc0ac78b8c3c539be231f4c0f4c
https://doi.org/10.1016/s0378-3758(02)00464-0
https://doi.org/10.1016/s0378-3758(02)00464-0
Publikováno v:
Applied Stochastic Models in Business and Industry. 18:207-218
Model fitting when the variance function depends on unknown parameters is a popular problem in many areas of research. Iterated estimators which are asymptotically equivalent to maximum likelihood estimators are proposed and their convergence is disc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b8cbd5f04d5c5d921bf5f2392feb3d7e
https://doi.org/10.1002/asmb.474
https://doi.org/10.1002/asmb.474
Autor:
Valerii V. Fedorov, Sergei L. Leonov
Publikováno v:
Drug Information Journal. 35:1373-1383
We discuss optimal experimental design issues for nonlinear models arising in dose response studies. The optimization is performed with respect to various criteria which depend on the Fisher information matrix. Special attention is given to models wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e441a13c0bc3779385384ad813fb179
https://doi.org/10.1177/009286150103500433
https://doi.org/10.1177/009286150103500433
Autor:
Sergei L. Leonov
Publikováno v:
IEEE Transactions on Aerospace and Electronic Systems. 37:832-848
Methods of clutter rejection are discussed which furnish an inherent counterpart of target tracking and detection algorithms. We describe how nonparametric curve estimation methods reduce the original sensor data to a "signal-plus-noise" model which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b17f10af1094783b095d9fdccf682146
https://doi.org/10.1109/7.953240
https://doi.org/10.1109/7.953240